A modern building with a unique triangular roof and a central spire.

Syracuse Hotel Guide. Hotels in Santa Lucia, Syracuse, Italy

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Check prices for these dates

This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

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Our top choices for Santa Lucia hotels

A historic building with ornate balconies, a grand entrance, and flags of the European Union and Italy.

1. Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (708 reviews)
The price is €103
includes taxes & fees
7 Nov - 8 Nov
Grande Albergo Alfeo
A modern hotel room with a flat-screen TV mounted on a dark wall, a white desk with a remote control, a bed with a black and white patterned bedspread, and a window with curtains.

2. Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (295 reviews)
"A really nice room, the bed was extremely comfortable and the staff were very friendly."
United Kingdom
Michael
The price is €66
includes taxes & fees
3 Nov - 4 Nov
Nostos rooms & Apartments
A neatly made bed with a dark quilt, white pillows, and a beige headboard. There are two bedside lamps on either side of the bed.

3. Melody rooms

Melody rooms
Santa Lucia
10.0 out of 10, Exceptional, (1 review)
The price is €40
includes taxes & fees
15 Oct - 16 Oct
Melody rooms
A rooftop terrace with lounge chairs, a hot tub, and a view of palm trees and buildings.

4. Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (300 reviews)
"Staff was very friendly and helpful"
Canada
Dena
The price is €160
includes taxes & fees
5 Nov - 6 Nov
Caportigia Boutique Hotel
A hotel room with a large bed, a chair, a small table, and a chandelier.

5. Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (49 reviews)
"Good central location & nice breakfast selection "
Australia
Alan
The price is €110
includes taxes & fees
1 Nov - 2 Nov
Hotel Palazzo Cavalieri
A room with a table and chairs, a view of a harbor with boats and buildings, and a clear sky.

6. Lakkios

Lakkios
3.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (81 reviews)
"The location of this place is amazing and that balcony view iconic. Staff super helpful too."
Canada
Marsel
The price is €93
includes taxes & fees
5 Nov - 6 Nov
Lakkios
A balcony with wicker chairs and a glass table overlooking a marina with boats.

7. Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (45 reviews)
"Beautiful accomodation, perfect location close to restauranys and attractions, clean room/all renovated with style, friendly personnel, nice view of the port"
Canada
Martine
The price is €171
includes taxes & fees
4 Nov - 5 Nov
Fortaleza Charme House
A balcony with a table set for two, a chair, and a view of a building with multiple windows and balconies.

8. B&B Nike

B&B Nike
Santa Lucia
9.0 out of 10, Wonderful, (93 reviews)
"The room and bathroom were large and clean. The mattress and sheets were fantastic. The room had air conditioning. The host was there at check in and was easily accessible. The location was great- just outside Ortigia. Parking was easy and close. An overall nice place to stay."
Canada
Chris
The price is €87
includes taxes & fees
7 Nov - 8 Nov
B&B Nike
An outdoor café with tables and chairs, a bar sign, and a restaurant sign.

9. Residence Agatocle

Residence Agatocle
Santa Lucia
8.8 out of 10, Excellent, (9 reviews)
"This was a perfect apartment for Siracusa and Ortiga. It was massive and the balcony was amazing - but the chairs were a little uncomfortable. I would highly recommend this apartment for a short or long stay"
United Kingdom
Janet
The price is €95
includes taxes & fees
3 Nov - 4 Nov
Residence Agatocle
A marina with numerous boats docked, a clear sky, and a building with outdoor seating.

10. Regina Margherita

Regina Margherita
Santa Lucia
7.8 out of 10, Good, (21 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
The price is €57
includes taxes & fees
3 Nov - 4 Nov
Regina Margherita
A multi-story building with balconies, a visible 'MOTORSUD' sign, and a 'PIAGGO' sign.

11. Syraka Design Rooms & Suites

Syraka Design Rooms & Suites
Santa Lucia
The price is €103
includes taxes & fees
2 Nov - 3 Nov
Syraka Design Rooms & Suites
A balcony with potted plants and a metal railing.

12. Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (388 reviews)
"Very old fashioned,poor shower,no coat hangers in wardrobe and no drawers. Hard bed,basic breakfast.Good location and quiet in hotel."
United Kingdom
PETER
The price is €83
includes taxes & fees
28 Oct - 29 Oct
Piccolo Hotel Casa Mia
A rooftop lounge area with lounge chairs and a large potted plant.

13. Le Camere Luxsury Rooms

Le Camere Luxsury Rooms
Santa Lucia
7.0 out of 10, Good, (2 reviews)
"Très belle chambre, mais forte odeur d’humidité, pas de FENÊTRE quartier type « cour des Miracles «  loin du centre historique, pas de supérette ou de restaurant dans le proche voisinage loin de toute commodité"
France
Philippe
The price is €78
includes taxes & fees
15 Oct - 16 Oct
Le Camere Luxsury Rooms
A modern bedroom with a bed, bedside table, and a unique feature of a table with a fire effect.

14. B&B IL MORO

B&B IL MORO
Santa Lucia
4.0 out of 10, (1 review)
"Personne sur place pour nous aider. La carte de la chambre était défectueuse dès l'arrivée. Par la suite l'électricité a manqué à 21h, nous avons du contacter les propriétaires via What's App dans le noir. Nous apprécions faire affaire avec des humains et non des applications impersonnelles et des vidéos. Le lit était petit et inconfortable. Pas d'oreiller d'extra ni de boîte de mouchoirs. Le quartier est lugubre."
Canada
Celine B. La
The price is €68
includes taxes & fees
25 Oct - 26 Oct
B&B IL MORO
A table with two wine glasses and a decorative item, viewed through a window overlooking a parking area with cars and greenery.

15. Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (44 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is €59
includes taxes & fees
21 Oct - 22 Oct
Gymnasium
A terrace with white tables and chairs, white umbrellas, and a view of the sea.

16. Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (134 reviews)
"We had an amazing time. Sabrina and Claudia were wonderful. The place is top notch in everything they do. The food was so fresh and delicious . I was sad when i had to leave them. High praise for this hotel. The views breath taking."
United States
Duane
The price is €239
includes taxes & fees
6 Nov - 7 Nov
Giuggiulena Villa
A balcony with a table set for tea, a book, and a view of a building and water.

17. Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (126 reviews)
"Very clean, well run and a decent breakfast. In a way it’s the perfect location: a 10-minute walk to Ortigia, but you are away from the over-touristy bits."
United States
David
The price is €80
includes taxes & fees
30 Oct - 31 Oct
Hotel Mediterraneo
A bedroom with a stone wall, a bed, a black shelving unit, a wicker chair, and a large green plant.

18. Isonzo Suites

Isonzo Suites
Santa Lucia
8.6 out of 10, Excellent, (8 reviews)
"."
Italy
Gianluca
The price is €78
includes taxes & fees
12 Nov - 13 Nov
Isonzo Suites
A bedroom with a stone wall, a bed with a wooden headboard, a tray with a plant, and a window with curtains.

19. B&B Siracusa

B&B Siracusa
Santa Lucia
8.8 out of 10, Excellent, (61 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is €79
includes taxes & fees
22 Oct - 23 Oct
B&B Siracusa
An open balcony with a table and chairs, potted plants, and a view of a building with balconies and windows.

20. Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
9.8 out of 10, Exceptional, (18 reviews)
"Clean, very convenient for exploring Ortigia. Nice continental breakfast."
United States
Mary
The price is €137
includes taxes & fees
2 Nov - 3 Nov
Calafatari B&B
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Lucia

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A terrace with white tables and chairs, white umbrellas, and a view of the sea.
Giuggiulena Villa
3.0 star property
10.0
Exceptional
134 reviews
View
An open balcony with a table and chairs, potted plants, and a view of a building with balconies and windows.
Calafatari B&B
3.0 star property
9.8
Exceptional
18 reviews
View
A room with a table and chairs, a view of a harbor with boats and buildings, and a clear sky.
Lakkios
3.0 star property
9.2
Wonderful
81 reviews
View
A modern hotel room with a flat-screen TV mounted on a dark wall, a white desk with a remote control, a bed with a black and white patterned bedspread, and a window with curtains.
Nostos rooms & Apartments
3.0 star property
9.0
Wonderful
295 reviews
View
A hotel room with a large bed, a chair, a small table, and a chandelier.
Hotel Palazzo Cavalieri
4.0 star property
9.0
Wonderful
49 reviews
View

Hotels recommended for families in Santa Lucia

A historic building with ornate balconies, a grand entrance, and flags of the European Union and Italy.

Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (708)
The price is €103
includes taxes & fees
7 Nov - 8 Nov
Grande Albergo Alfeo

Where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.
A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

Ancient ruins with a large amphitheater surrounded by trees.
Photo by William Keller
Open Photo by William Keller

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

A natural rock arch over a body of water with people paddling in kayaks.
Photo by Salvo Cannizzaro
Open Photo by Salvo Cannizzaro

Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

An aerial view of a coastal city with a prominent fortified structure and a densely built urban area in the background.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

Top Santa Lucia Hotel Reviews

Grand Hotel Ortigia Siracusa

Grand Hotel Ortigia Siracusa

10/10 Excellent
"A splendid, classic property with first rate service, comfortable beds and a glorious breakfast on a breathtaking outdoor terrace. Wish we could have stayed longer."
Richard 1-night trip
Posted 17 hours ago
Grand Hotel Ortigia Siracusa

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Lucia?
Based on our traveller data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel offers free breakfast and a restaurant. Other good choices for your stay in the area include Nostos rooms & Apartments and Caportigia Boutique Hotel.
How many hotels will I find in Santa Lucia?
Expedia has 313 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

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