Holiday Homes in South Carolina Midlands

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
28 Nov - 30 Nov
In two weeks
5 Dec - 7 Dec
In one month
19 Dec - 21 Dec
In two months
16 Jan - 18 Jan

Featured Holiday Homes in South Carolina Midlands and around

Fridge, microwave, oven, stovetop
Peaceful Farm Getaway

Holiday Home in Mullins

10.0 out of 10, Exceptional, (30)
"The property is fantastic and so are the owners. Do not hesitate to book this property.!"
United States
Teddy R.
The price is €188
includes taxes & fees
14 Dec - 15 Dec
Peaceful Farm Getaway
Property grounds
Haffa's Unrivaled Expeditions At Lake Murray Palmetto Retreat

Holiday Home in Gilbert

9.6 out of 10, Exceptional, (7)
"Perfect location and great hosts!! "
United States
Cindy N.
The price is €242
includes taxes & fees
8 Dec - 9 Dec
Haffa's Unrivaled Expeditions At Lake Murray Palmetto Retreat
1 bedroom, free WiFi, bed sheets
1972 Airstream luxury tiny living at it's best in Columbia near Lake Murray!

Holiday Home in Columbia

2.0 star property
9.8 out of 10, Exceptional, (25)
"We enjoy our stay at this quaint quiet place. Loved the outdoor sitting area and the airstream was clean an cutely decorated."
United States
Marian A.
The price is €152
includes taxes & fees
20 Dec - 21 Dec
1972 Airstream luxury tiny living at it's best in Columbia near Lake Murray!
Exterior
Entire Historic Home - Carolina Getaway

Holiday Home in Williston

10.0 out of 10, Exceptional, (11)
"Enjoyed our stay at Ruby’s place on our way home from Charleston."
United States
Ryan D.
The price is €198
includes taxes & fees
20 Nov - 21 Nov
Entire Historic Home - Carolina Getaway
Exterior
Large late1800's home within walking distance to Opera House and downtown.

Holiday Home in Newberry

9.8 out of 10, Exceptional, (37)
"Enjoyed our stay visiting family nearby! Great location, beautiful cozy home, and it met all our needs!"
United States
Mary K.
The price is €307
includes taxes & fees
1 Dec - 2 Dec
Large late1800's home within walking distance to Opera House and downtown.
Fridge, microwave, oven, stovetop
The Last Resort at Martins Landing

Holiday Home in Hollands Landing

3.0 star property
9.8 out of 10, Exceptional, (34)
"We stayed at The Last Resort after a fun day of boating on the Lake. Great location with views of the lake and near great choices for lunch and dinner."
United States
Jody D.
The price is €181
includes taxes & fees
9 Dec - 10 Dec
The Last Resort at Martins Landing
2 bedrooms, desk, iron/ironing board, travel cot
Double King 2bed/2 bath in Downtown Columbia!

Holiday Home in Columbia

2.0 star property
9.8 out of 10, Exceptional, (7)
"Clean, quaint, updated kitchen and easy access to the main drag. "
United States
John W.
The price is €351
includes taxes & fees
7 Dec - 8 Dec
Double King 2bed/2 bath in Downtown Columbia!
Property grounds
Cozy and Quiet- Private Upstairs Duplex

Holiday Home in Columbia

10.0 out of 10, Exceptional, (8)
"This duplex was the perfect place for our 3 night stay in SC. Very clean, comfortable and quite as promised. Anna was very nice and provided lots of information about the area. We were they for a show at the arena and when to one of the parks and the zoo. "
United States
Terri T.
The price is €144
includes taxes & fees
30 Nov - 1 Dec
Cozy and Quiet- Private Upstairs Duplex
Fridge, microwave, oven, stovetop
Red Fox Farms Guest House

Holiday Home in Lancaster

10.0 out of 10, Exceptional, (28)
"Host was very nice and the property was very clean and neat. Very quiet and peaceful."
United States
Bailey
The price is €204
includes taxes & fees
1 Dec - 2 Dec
Red Fox Farms Guest House
Smart TV, fireplace, video games
Beautiful 3 BD/2 BA Home with Ping-Pong, Arcade, Grill, and 2 Dining Rooms

Holiday Home in Columbia

9.8 out of 10, Exceptional, (7)
"The house was nice spacious and everything we needed. "
United States
John R.
The price is €313
includes taxes & fees
7 Dec - 8 Dec
Beautiful 3 BD/2 BA Home with Ping-Pong, Arcade, Grill, and 2 Dining Rooms
Outdoor dining
The Turquoise Door in Town of Lexington

Holiday Home in Lexington

9.8 out of 10, Exceptional, (114)
"Such a cute property and very gracious host "
United States
Tracy C.
The price is €266
includes taxes & fees
1 Dec - 2 Dec
The Turquoise Door in Town of Lexington
Fridge, microwave, oven, stovetop
Downtown Aiken- The Collins Property

Holiday Home in Aiken

9.8 out of 10, Exceptional, (51)
"Great property! We enjoyed our stay there!"
United States
Bobbie Jean G.
The price is €232
includes taxes & fees
23 Nov - 24 Nov
Downtown Aiken- The Collins Property
Fridge, microwave, oven, stovetop
Walking distance from one of South Carolina's top Medical centers.

Holiday Home in Florence

9.8 out of 10, Exceptional, (42)
"The house was beautiful. We would stay there again!!"
United States
Stephanie L.
The price is €204
includes taxes & fees
25 Nov - 26 Nov
Walking distance from one of South Carolina's top Medical centers.
Exterior
Cozy 3-bedroom Home in West Columbia located only 5 minutes from downtown vista.

Holiday Home in West Columbia

8.8 out of 10, Excellent, (30)
"The house had everything we needed and was conveniently located for everything we needed to do. "
United States
Kim G.
The price is €170
includes taxes & fees
1 Dec - 2 Dec
Cozy 3-bedroom Home in West Columbia located only 5 minutes from downtown vista.
Smart TV, offices
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Holiday Home in Santee

10.0 out of 10, Exceptional, (36)
"Amazing host, comfy furniture, the fenced in yard was perfect for our fur babies! Hope to stay here again. 1.2 miles away from I-95! "
United States
Lauren B.
The price is €291
includes taxes & fees
23 Nov - 24 Nov
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Property grounds
In 1840 Burn Cottage

Holiday Home in Society Hill

9.8 out of 10, Exceptional, (33)
"Nice historic house provided authentic late-1800s three night stay. Enjoyed our stay."
United States
Ansel C.
The price is €183
includes taxes & fees
1 Dec - 2 Dec
In 1840 Burn Cottage
Fridge, microwave, oven, stovetop
5 mins to Fort Jackson - The Wooded Hilltop Ranch

Holiday Home in Columbia

5 mins to Fort Jackson - The Wooded Hilltop Ranch
Fridge, microwave, oven, stovetop
Charming 2-bedroom townhome with AC and WiFi in peaceful Summerton

Holiday Home in Summerton

The price is €286
includes taxes & fees
15 Dec - 16 Dec
Charming 2-bedroom townhome with AC and WiFi in peaceful Summerton
Fridge, microwave, oven, stovetop
Cozy Party House in the woods

Holiday Home in Waxhaw

2.0 star property
8.6 out of 10, Excellent, (7)
"Clean, roomy, quiet… lovely for our weekend getaway to quaint little town with so much to offer!"
United States
Cara G.
The price is €298
includes taxes & fees
20 Nov - 21 Nov
Cozy Party House in the woods
Exterior
Camden Cottage

Holiday Home in Camden

10.0 out of 10, Exceptional, (56)
"In town for a weekend track event at CMP, and this cottage was exactly what we needed. Easy drive to CMP, close to dining and shopping in Camden - perfect. Thank you for a wonderful experience!"
United States
Greg J.
The price is €181
includes taxes & fees
29 Nov - 30 Nov
Camden Cottage
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top South Carolina Midlands Hotel Reviews

La Quinta Inn by Wyndham Columbia NE/Fort Jackson

La Quinta Inn by Wyndham Columbia NE/Fort Jackson

10/10 Excellent
"Very clean and modern style. Bed was comfortable and I liked that the shower had a soap, shampoo and conditioner dispenser in the bathroom rather than those small 1oz container . All in all it’s a great hotel. "
Nicole 1-night trip
Posted 2 days ago
La Quinta Inn by Wyndham Columbia NE/Fort Jackson

Find out more about South Carolina Midlands

South Carolina Midlands Holiday Homes information

Number of reviews
Accommodation
 Holiday Homes
Lowest Price
Highest Price

Explore a world of travel with Expedia