San Antonio Hotel Guide - South Texas Medical Center hotels in San Antonio, United States of America.

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27 Dec - 28 Dec
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9 Jan - 11 Jan

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Our top choices for South Texas Medical Center hotels

Pool
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
2.5 star property
Medical Center District, 1 km from South Texas Medical Center
9.0 out of 10, Wonderful, (1002)
"Everything was great, staff really kind ..."
United States
traci
The price is €82
includes taxes & fees
31 Dec - 1 Jan 2026
Fairfield Inn & Suites by Marriott San Antonio Medical Center
Exterior
Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District, 1.3 km from South Texas Medical Center
8.8 out of 10, Excellent, (1005)
"Clean room, very close to medical center, and personnel at check in were very friendly."
United States
Melinda
The price is €89
includes taxes & fees
9 Jan - 10 Jan 2026
Courtyard by Marriott Medical Center San Antonio
Lobby
Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District, 2.9 km from South Texas Medical Center
9.2 out of 10, Wonderful, (1288)
"Great place to stay and visit "
United States
Harry
The price is €90
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Inn & Suites San Antonio Northwest Medical Center
Front of property
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District, 2.4 km from South Texas Medical Center
8.4 out of 10, Very good, (3128)
"Great place "
United States
Amado
The price is €89
includes taxes & fees
8 Jan - 9 Jan 2026
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
Indoor pool, outdoor pool
The Westin San Antonio North

The Westin San Antonio North

The Westin San Antonio North
4.0 star property
3.2 km from South Texas Medical Center
8.6 out of 10, Excellent, (1228)
"Love this hotel!"
United States
Nora
The price is €84
includes taxes & fees
9 Jan - 10 Jan 2026
The Westin San Antonio North
Premium bedding, pillow-top beds, in-room safe, desk
SpringHill Suites by Marriott San Antonio Medical Center/NW

SpringHill Suites by Marriott San Antonio Medical Center/NW

SpringHill Suites by Marriott San Antonio Medical Center/NW
3.0 star property
Medical Center District, 3.2 km from South Texas Medical Center
8.8 out of 10, Excellent, (1001)
"good staff. good stay"
United States
Divya
The price is €101
includes taxes & fees
2 Jan - 3 Jan 2026
SpringHill Suites by Marriott San Antonio Medical Center/NW
Reception
Park Inn by Radisson

Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District, 0.9 km from South Texas Medical Center
7.2 out of 10, Good, (1001)
"Staff were amazing, and everything else was great too. "
United States
Maximilian
The price is €60
includes taxes & fees
23 Jan - 24 Jan 2026
Park Inn by Radisson
Front of property
Atria Inn & Suites

Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District, 2.2 km from South Texas Medical Center
7.4 out of 10, Good, (274)
"Nice, comfortable space for a reasonable price. "
United States
Cynthia
Atria Inn & Suites
Desk, laptop workspace, blackout curtains, free WiFi
Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District, 2.7 km from South Texas Medical Center
7.2 out of 10, Good, (222)
"Good stay and safe area"
United States
Mario
The price is €53
includes taxes & fees
4 Jan - 5 Jan 2026
Studio 6 San Antonio, Tx - Northwest Medical Center
Exterior
OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District, 3.1 km from South Texas Medical Center
7.2 out of 10, Good, (225)
"Always great stay"
United States
Juan
The price is €62
includes taxes & fees
28 Dec - 29 Dec
OYO Inn & Suites Medical Center San Antonio
Free daily on-the-go breakfast
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
3.0 star property
Medical Center District, 2.6 km from South Texas Medical Center
6.8 out of 10, (1002)
"Easy and convenient location "
United States
Monique
The price is €58
includes taxes & fees
18 Jan - 19 Jan 2026
Country Inn & Suites by Radisson, San Antonio Medical Center, TX
Desk, laptop workspace, free WiFi, bed sheets
Studio 6 San Antonio, TX - Medical Center

Studio 6 San Antonio, TX - Medical Center

Studio 6 San Antonio, TX - Medical Center
2.0 star property
Medical Center District, 1.3 km from South Texas Medical Center
6.6 out of 10, (795)
"Very convenient"
United States
Melony
The price is €49
includes taxes & fees
30 Dec - 31 Dec
Studio 6 San Antonio, TX - Medical Center
Lounge
Motel 6 San Antonio, TX - Fiesta Trails

Motel 6 San Antonio, TX - Fiesta Trails

Motel 6 San Antonio, TX - Fiesta Trails
2.0 star property
2.9 km from South Texas Medical Center
6.6 out of 10, (980)
"Our stay was very pleasant. TY ANNA FOR OUR CHECK-IN"
United States
Joben
The price is €49
includes taxes & fees
28 Dec - 29 Dec
Motel 6 San Antonio, TX - Fiesta Trails
Basic Room, Multiple Beds, Non Smoking
Flex Studios

Flex Studios

Flex Studios
2.5 star property
Medical Center District, 2.7 km from South Texas Medical Center
6.0 out of 10, (498)
"heb is nearby. "
United States
Sayeed
The price is €42
includes taxes & fees
28 Dec - 29 Dec
Flex Studios
Free WiFi, bed sheets
Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District, 2.8 km from South Texas Medical Center
6.0 out of 10, (1000)
"Great experience "
United States
John
The price is €43
includes taxes & fees
8 Jan - 9 Jan 2026
Motel 6 San Antonio, TX - Northwest Medical Center
Lobby
San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District, 3.3 km from South Texas Medical Center
8.6 out of 10, Excellent, (1004)
"Best hotel!"
United States
Valeria
The price is €111
includes taxes & fees
2 Jan - 3 Jan 2026
San Antonio Marriott Northwest Medical Center
Lobby sitting area
Hyatt Place San Antonio-Northwest/Medical Center

Hyatt Place San Antonio-Northwest/Medical Center

Hyatt Place San Antonio-Northwest/Medical Center
3.0 star property
3.4 km from South Texas Medical Center
8.2 out of 10, Very good, (1003)
"Really enjoyed our stay. "
United States
Juan
The price is €85
includes taxes & fees
5 Jan - 6 Jan 2026
Hyatt Place San Antonio-Northwest/Medical Center
Exterior
Sonesta ES Suites San Antonio Northwest - Medical Center

Sonesta ES Suites San Antonio Northwest - Medical Center

Sonesta ES Suites San Antonio Northwest - Medical Center
3.0 star property
3.3 km from South Texas Medical Center
8.2 out of 10, Very good, (1001)
"Very good value. Clean, respectful staff, nice breakfast "
United States
Mary Jo
The price is €67
includes taxes & fees
15 Jan - 16 Jan 2026
Sonesta ES Suites San Antonio Northwest - Medical Center
Outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas, pool loungers
Homewood Suites by Hilton San Antonio Northwest

Homewood Suites by Hilton San Antonio Northwest

Homewood Suites by Hilton San Antonio Northwest
3.0 star property
3.3 km from South Texas Medical Center
8.4 out of 10, Very good, (1000)
"Everything was great. Close to the zoo and Riverwalk. "
United States
Elizabeth
The price is €73
includes taxes & fees
4 Jan - 5 Jan 2026
Homewood Suites by Hilton San Antonio Northwest
Exterior
Hampton Inn & Suites San Antonio Northwest/Medical Center

Hampton Inn & Suites San Antonio Northwest/Medical Center

Hampton Inn & Suites San Antonio Northwest/Medical Center
2.5 star property
Northwest Side, 4.2 km from South Texas Medical Center
8.4 out of 10, Very good, (1102)
"Great hotel!! "
United States
Dalia
The price is €87
includes taxes & fees
8 Jan - 9 Jan 2026
Hampton Inn & Suites San Antonio Northwest/Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South Texas Medical Center Hotel Reviews

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

10/10 Excellent
"Excellent facility. Great amenities that ibclude breakfast and dinner. "
Sara 1-night trip
Posted 1 day ago
Drury Inn & Suites San Antonio Northwest Medical Center

Hotels near other South Texas Medical Center attractions

Cinemark San Antonio 16

You can take time to visit Cinemark San Antonio 16 during your travels to San Antonio.
See properties

USAA Corporate Office Headquarters

USAA Corporate Office Headquarters is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Stroll along the riverfront or attend a sporting event in this family-friendly area.
See properties

Frequently asked questions

What's the area like around South Texas Medical Center?
South Texas Medical Center is located in a walkable area of San Antonio known for its stunning river views and cycling. If you're looking for a convenient place to stay, take a look at the 40 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay close to South Texas Medical Center?
Fairfield Inn & Suites by Marriott San Antonio Medical Center is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and free parking. It's located just a short 0.6 mi (1 km) from South Texas Medical Center. Other good options close by include Park Inn by Radisson and Courtyard by Marriott Medical Center San Antonio.
How many hotels should I expect to find close to South Texas Medical Center?
Expedia has 40 hotels and other accommodation options within a mile from South Texas Medical Center.
If I need to cancel the hotel reservation for my stay near South Texas Medical Center, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near South Texas Medical Center.
What can I see and do near South Texas Medical Center?
You can enjoy live performances at Woodlawn Theater and Sheldon Vexler Theatre. Create some family memories at Crystal Ice Palace and Monster Mini Golf. Looking for a little shopping break? A trip to Huebner Oaks, Ingram Park Mall and Wonderland of the Americas Mall might be just the ticket while you're in the area around South Texas Medical Center.