Photo by Southernmost Illinois Tourism Bureau

Southwest Illinois Hotels

Start date: Check-in selected.
To Date
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Southwest Illinois hotels

Days Inn by Wyndham Mount Vernon

2.0 star property
6.6 out of 10, (1005)
"Staff was very friendly "
The price is €62
includes taxes & fees
13 Oct - 14 Oct
Days Inn by Wyndham Mount Vernon

Drury Plaza Hotel Mt. Vernon

3.0 star property
9.6 out of 10, Exceptional, (1477)
"Excellent hotel! Clean, excellent breakfast, and friendly staff!"
The price is €91
includes taxes & fees
26 Oct - 27 Oct
Drury Plaza Hotel Mt. Vernon

Super 8 by Wyndham Carbondale

2.0 star property
7.4 out of 10, Good, (1005)
"The hotel was very clean & the breakfast was more than enough "
The price is €64
includes taxes & fees
14 Oct - 15 Oct
Super 8 by Wyndham Carbondale

Holiday Inn Carbondale-Conference Center by IHG

3.0 star property
8.8 out of 10, Excellent, (608)
"Great hotel and very nice ataff"
The price is €90
includes taxes & fees
9 Nov - 10 Nov
Holiday Inn Carbondale-Conference Center by IHG

SureStay Hotel by Best Western Whittington Rend Lake

2.5 star property
8.8 out of 10, Excellent, (872)
"Great place to stay."
The price is €81
includes taxes & fees
16 Oct - 17 Oct
SureStay Hotel by Best Western Whittington Rend Lake

Comfort Suites Mount Vernon

2.5 star property
8.8 out of 10, Excellent, (1013)
"Our stay was very good. "
The price is €105
includes taxes & fees
12 Oct - 13 Oct
Comfort Suites Mount Vernon

University Inn of Carbondale

2.5 star property
6.0 out of 10, (292)
"Place was "
University Inn of Carbondale

Super 8 by Wyndham Mt. Vernon IL

2.5 star property
7.8 out of 10, Good, (1001)
"Was just off Route 57 and easy to get to!"
The price is €60
includes taxes & fees
2 Nov - 3 Nov
Super 8 by Wyndham Mt. Vernon IL

Drury Inn & Suites Marion

3.0 star property
9.4 out of 10, Exceptional, (1003)
"We always like staying at this location specially "
The price is €67
includes taxes & fees
2 Nov - 3 Nov
Drury Inn & Suites Marion

Quality Inn & Suites Vandalia near I-70 and Hwy 51

2.5 star property
8.4 out of 10, Very good, (1013)
"Room was nice, shower was really good "
The price is €63
includes taxes & fees
2 Nov - 3 Nov
Quality Inn & Suites Vandalia near I-70 and Hwy 51

Comfort Inn & Suites Marion I-57

2.5 star property
9.2 out of 10, Wonderful, (1005)
"Wonderful place to stay!"
The price is €111
includes taxes & fees
30 Oct - 31 Oct
Comfort Inn & Suites Marion I-57

Baymont by Wyndham Marion

2.5 star property
8.4 out of 10, Very good, (1038)
"Room was nice and convenient to interstate"
The price is €89
includes taxes & fees
13 Oct - 14 Oct
Baymont by Wyndham Marion

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 star property
9.4 out of 10, Exceptional, (485)
"Clean room, friendly staff"
The price is €106
includes taxes & fees
12 Oct - 13 Oct
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Super 8 by Wyndham Greenville

2.0 star property
8.0 out of 10, Very good, (737)
"It’s not super fancy, as you’d expect, but the place was decent and seemed clean, the staff was very friendly and helpful, and the prices are decent if you need a quick stay. "
The price is €62
includes taxes & fees
12 Oct - 13 Oct
Super 8 by Wyndham Greenville

Quality Inn And Suites

2.5 star property
7.4 out of 10, Good, (1005)
"Disgusting don’t stay here!!!"
The price is €73
includes taxes & fees
16 Oct - 17 Oct
Quality Inn And Suites

Red Lion Inn & Suites Pontoon Beach

2.5 star property
7.8 out of 10, Good, (526)
"Very clean, friendly, delicious breakfast, highly recommended"
The price is €63
includes taxes & fees
15 Oct - 16 Oct
Red Lion Inn & Suites Pontoon Beach

Best Western Marion Hotel

2.5 star property
8.2 out of 10, Very good, (1005)
"The hotel was very nice!"
The price is €86
includes taxes & fees
16 Oct - 17 Oct
Best Western Marion Hotel

Quality Inn & Suites near St. Louis and I-255

2.5 star property
7.4 out of 10, Good, (1005)
"It meets my expectations and the staff were nice."
The price is €70
includes taxes & fees
20 Oct - 21 Oct
Quality Inn & Suites near St. Louis and I-255

Quality Inn O'Fallon IL - St. Louis

3.0 star property
7.4 out of 10, Good, (1009)
"Need to work on the breakfast options. "
The price is €61
includes taxes & fees
12 Oct - 13 Oct
Quality Inn O'Fallon IL - St. Louis

DoubleTree by Hilton Mt. Vernon

4.0 star property
8.2 out of 10, Very good, (747)
"Beautiful facilities at Hilton."
The price is €123
includes taxes & fees
30 Oct - 31 Oct
DoubleTree by Hilton Mt. Vernon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Showing deals for:17 Oct - 19 Oct
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Central United States attractions

Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

Southern Illinois featuring a lake or waterhole and forest scenes
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Top Southwest Illinois Hotel Reviews

More cheap stays in Southwest Illinois

More cheap stays in Southwest Illinois

Explore a world of travel with Expedia

Explore a world of travel with Expedia