St. Charles Hotel Guide - Hotels with Spa in St. Charles, St. Louis

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Check availability on St. Charles Hotels with Spa

Tonight
30 Nov - 1 Dec
Tomorrow
1 Dec - 2 Dec
Next weekend
5 Dec - 7 Dec
In two weeks
12 Dec - 14 Dec

Top St. Charles Hotels with Spa

Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 star property
St. Charles
8.4 out of 10, Very good, (1009)
"Beautiful hotel, spacious guestroom, comfortable beds, kind and helpful staff! "
United States
Heather
The price is €159
includes taxes & fees
7 Dec - 8 Dec
Ameristar Casino Resort and Spa
Couples treatment room(s), hot tub, body treatments, aromatherapy
Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1006)
"The staff was amazing. The bed was so comfortable. "
United States
Mary
The price is €418
includes taxes & fees
1 Jan - 2 Jan 2026
Four Seasons Hotel St Louis
Massages
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1475)
"Great staff and clean room"
United States
Chris
The price is €158
includes taxes & fees
21 Dec - 22 Dec
21C Museum Hotel St Louis
Body treatments, aromatherapy, hot stone massages, deep-tissue massages
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5.0 star property
Clayton
9.2 out of 10, Wonderful, (553)
"Service is exceptional!!!"
United States
Jorge
The price is €502
includes taxes & fees
21 Dec - 22 Dec
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"The front desk staff was amazing, they were all very kind and helpful. Our room got upgraded for free with a partial view of the arch. Which made my kids extremely happy. The room was really nice and clean. The food was very good with a great selection. My family will definitely be staying again when we go back to Saint Louis. "
Felicia 1-night trip
Posted 1 day ago
Drury Plaza Hotel St. Louis at the Arch

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Frequently asked questions

Looking for a spa hotel in St. Charles?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travellers highly recommend the restaurants in St. Charles. Enjoy the historical sites and riverfront during your holiday. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your stay.
What is the best spa hotel in St. Charles?
Ameristar Casino Resort and Spa is a top luxury spa hotel featuring 6 restaurants, a casino and a 24-hour fitness centre. Treat yourself to a facial, body scrub or hydrotherapy at Ara.
How many spa hotels will I find in St. Charles?
Among Expedia's 158 accommodation options in St. Charles, there is 1 spa hotel.
What's there to see and do in St. Charles?
Experience all that St. Charles has to offer when you visit Historic Main Street, Katy Trail and St Charles Convention Center. If you have some spare time during your trip, you might want to check out Ameristar Casino St. Charles and Fast Lane Classic Cars.
What is a St. Charles spa hotel?
Spa hotels in St. Charles provide lodging and have a full on-site spa which offers services such as couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on holiday.