A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

St. Charles Hotel Guide - Hotels with Spa in St. Charles, St. Louis

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Check availability on St. Charles Hotels with Spa

Tonight
29 Aug - 30 Aug
Tomorrow
30 Aug - 31 Aug
Next weekend
4 Sept - 6 Sept
In two weeks
11 Sept - 13 Sept

Our top choices for St. Charles hotels with a spa

A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A bakery display case with various pastries and cakes.

1. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
€181
includes taxes & fees
7 Sept - 8 Sept
Ameristar Casino Resort and Spa

2. Truitt Hotel

Truitt Hotel
Lafayette Square
€176
includes taxes & fees
31 Aug - 1 Sept
Truitt Hotel
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A modern lobby with a large glass sphere, seating areas, and a reception desk.

3. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
€149
includes taxes & fees
20 Sept - 21 Sept
21C Museum Hotel St Louis
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
A bar area with leather seating, a bar counter, and shelves of bottles.
A couple standing on a balcony with a cityscape view.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.

4. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
€553
includes taxes & fees
20 Sept - 21 Sept
The Ritz-Carlton, St. Louis
A couple relaxing by a window overlooking a bridge and water.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.

5. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
€376
includes taxes & fees
9 Sept - 10 Sept
Four Seasons Hotel St Louis
View all properties

Choose what matters most at spa hotels in St. Charles

Pool
Hot tub
Breakfast included
4 stars
5 stars

Top St. Charles Hotel Reviews

Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

8/10 Good
"Nice place and can walk right out to activities and restaurants the only complaint i have was the ac unit everytime it kicked on it was very loud and woke me up"
tina 1-night trip
Posted 4 hours ago
Drury Plaza Hotel St. Louis Union Station
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

8/10 Good
"I requested extra town and never got them, other than that it was a great hotel."
Dwight 3-night trip
Posted 16 hours ago
Country Inn & Suites by Radisson, St. Charles Historic District
Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters

10/10 Excellent
"Nice spot to sleep"
Anthony 1-night trip
Posted 2 days ago
Hampton Inn St. Charles St. Peters
Embassy Suites by Hilton St. Louis St. Charles

Embassy Suites by Hilton St. Louis St. Charles

10/10 Excellent
"Good location in Saint Charles, MO. Plenty of restaurants near by. Breakfast was a 6 out of 10. Good evening drinks and snacks"
gregory 7-night trip
Posted 5 days ago
Embassy Suites by Hilton St. Louis St. Charles

Frequently asked questions

Looking for a spa hotel in St. Charles?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travellers highly recommend the restaurants in St. Charles. Enjoy the historical sites and riverfront during your holiday. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your stay.
What is the best spa hotel in St. Charles?
Ameristar Casino Resort and Spa is a top luxury spa hotel featuring 6 restaurants, a casino, a 24-hour fitness centre and an outdoor pool. Treat yourself to a facial, body scrub or hydrotherapy at Ara.
How many spa hotels will I find in St. Charles?
Among Expedia's 170 accommodation options in St. Charles, there is 1 spa hotel.
What's there to see and do in St. Charles?
Experience all that St. Charles has to offer when you visit Historic Main Street, Frontier Park and Katy Trail. If you have some spare time during your trip, you might want to check out Lewis & Clark Boathouse and Nature Center and St Charles Convention Center.
What is a St. Charles spa hotel?
Spa hotels in St. Charles provide lodging and have a full on-site spa which offers services such as couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on holiday.