St. Charles Hotel Guide - Hotels with Spa in St. Charles, St. Louis

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on St. Charles Hotels with Spa

Next weekend
5 Jun - 7 Jun
In two weeks
12 Jun - 14 Jun

Our top choices for St. Charles hotels with a spa

Hot tub, body treatments, hydrotherapy, aromatherapy, body scrubs

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.6 out of 10, Excellent, (1,002 reviews)
  • cleanliness
    Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
The price is €174
includes taxes & fees
1 Jul - 2 Jul
Ameristar Casino Resort and Spa
Massages

21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1,871 reviews)
  • cleanliness
    Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
The price is €174
includes taxes & fees
7 Jun - 8 Jun
21C Museum Hotel St Louis
Couples treatment room(s), hot tub, body treatments, aromatherapy

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
The price is €356
includes taxes & fees
14 Jun - 15 Jun
Four Seasons Hotel St Louis
Body treatments, aromatherapy, hot stone massages, deep-tissue massages

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Clayton
9.2 out of 10, Wonderful, (568 reviews)
  • cleanliness
    Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
The price is €500
includes taxes & fees
7 Jun - 8 Jun
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at spa hotels in St. Charles

Pool
Hot tub

Top St. Charles Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

10/10 Excellent
"I was pleasantly surprised by how lovely the Clayton Plaza hotel is. The room had all the amenities of a fancy hotel. The breakfast was absolutely delicious with many options and full omelette and waffle bar and restaurant table seating available. The staff was friendly and helpful. Highly recommend this hotel, great location and very reasonable pricing!"
Ellen 3-night trip
Posted less than an hour ago
Clayton Plaza Hotel & Extended Stay

Frequently asked questions

Looking for a spa hotel in St. Charles?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travellers highly recommend the restaurants in St. Charles. Enjoy the historical sites and riverfront during your holiday. Hotels with spas are a great way to break away from your daily routine and add a layer of luxury to your stay.
What is the best spa hotel in St. Charles?
Ameristar Casino Resort and Spa is a top luxury spa hotel featuring 6 restaurants, a casino, a 24-hour fitness centre and an outdoor pool. Treat yourself to a facial, body scrub or hydrotherapy at Ara.
How many spa hotels will I find in St. Charles?
Among Expedia's 173 accommodation options in St. Charles, there is 1 spa hotel.
What's there to see and do in St. Charles?
Experience all that St. Charles has to offer when you visit Historic Main Street, First Missouri State Capitol Historic Site and Katy Trail. If you have some spare time during your trip, you might want to check out Lewis & Clark Boathouse and Nature Center and St Charles Convention Center.
What is a St. Charles spa hotel?
Spa hotels in St. Charles provide lodging and have a full on-site spa which offers services such as couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on holiday.