Upstate South Carolina Hotel Guide - Boutique Hotels in Upstate South Carolina, South Carolina

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Upstate South Carolina Boutique Hotels

Top Upstate South Carolina Boutique Hotels

Hotel Domestique
Bar (on property)

Hotel Domestique

4.0 star property
9.6 out of 10, Exceptional, (30)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
The price is €393
includes taxes & fees
26 Aug - 27 Aug
Hotel Domestique
Inn @ Clemson
Lobby lounge

Inn @ Clemson

2.5 star property
8.2 out of 10, Very good, (1007)
"This hotel was a great value. The staff was really helpful and friendly"
The price is €84
includes taxes & fees
1 Sept - 2 Sept
Inn @ Clemson
The Bleckley Inn
Property entrance

The Bleckley Inn

3.5 star property
9.8 out of 10, Exceptional, (400)
"Beautiful hotel in beautiful downtown Anderson. "
The price is €234
includes taxes & fees
26 Aug - 27 Aug
The Bleckley Inn
Hyatt Place Greenville/Haywood
Lobby

Hyatt Place Greenville/Haywood

3.0 star property
7.8 out of 10, Good, (1002)
"Great hotel in an amazing area ! "
The price is €79
includes taxes & fees
13 Sept - 14 Sept
Hyatt Place Greenville/Haywood
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Upstate South Carolina Hotel Reviews

Inn @ Clemson

Inn @ Clemson

10/10 Excellent
"The Inn was a nice place to stay. Beds were comfortable. This was just an overnight stay on way hime from Beach. "
Shirl 1-night trip
Posted 4 days ago
Inn @ Clemson

Explore a world of travel with Expedia

Explore a world of travel with Expedia