Cheap Flights from Santiago to Panama City

View €360 flight on Sun, 31 Aug 2025Opens in a new window

Popular airlines from Santiago to Panama City

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Cheap flights from Santiago to Panama City (SCL-PTY)

Prices were available within the past 7 days and start at €360 for one-way flights and €566 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Mon, 10 Nov - Fri, 28 Nov
SCL
Santiago
PTY
Panama City
€566 Return, found 3 days ago
€566
Return
found 3 days ago
Select Copa flight, departing Mon, 10 Nov from Santiago to Panama City, returning Fri, 28 Nov, priced at €566 found 3 days ago
Copa
Mon, 10 Nov - Fri, 28 Nov
SCL
Santiago
PTY
Panama City
€579 Return, found 3 days ago
€579
Return
found 3 days ago
Select Copa flight, departing Mon, 10 Nov from Santiago to Panama City, returning Fri, 28 Nov, priced at €579 found 3 days ago
Copa
Mon, 10 Nov - Fri, 28 Nov
SCL
Santiago
PTY
Panama City
€592 Return, found 3 days ago
€592
Return
found 3 days ago
Select Copa flight, departing Mon, 10 Nov from Santiago to Panama City, returning Fri, 28 Nov, priced at €592 found 3 days ago
avianca
Mon, 10 Nov - Fri, 28 Nov
SCL
Santiago
PTY
Panama City
€741 Return, found 3 days ago
€741
Return
found 3 days ago
Select avianca flight, departing Mon, 10 Nov from Santiago to Panama City, returning Fri, 28 Nov, priced at €741 found 3 days ago
Aeromexico
Mon, 10 Nov - Fri, 28 Nov
SCL
Santiago
PTY
Panama City
€753 Return, found 3 days ago
€753
Return
found 3 days ago
Select Aeromexico flight, departing Mon, 10 Nov from Santiago to Panama City, returning Fri, 28 Nov, priced at €753 found 3 days ago
American Airlines
Mon, 10 Nov - Fri, 28 Nov
SCL
Santiago
PTY
Panama City
€1,235 Return, found 3 days ago
€1,235
Return
found 3 days ago
Select American Airlines flight, departing Mon, 10 Nov from Santiago to Panama City, returning Fri, 28 Nov, priced at €1,235 found 3 days ago

Find the cheapest month to fly from Santiago (SCL) to Panama City (PTY)

November is typically the cheapest month to fly

From €305 - €646 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.