Cheap Flights from Des Moines to Palo Alto

View €112 flight on Sun, 24 Aug 2025Opens in a new window

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Cheap flights from Des Moines to Palo Alto (DSM-SJC)

Prices were available within the past 7 days and start at €112 for one-way flights and €223 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Sun, 24 Aug - Sun, 31 Aug
DSM
Des Moines
SFO
San Francisco
€223 Return, found 1 day ago
€223
Return
found 1 day ago
Select Delta flight, departing Sun, 24 Aug from Des Moines to San Francisco, returning Sun, 31 Aug, priced at €223 found 1 day ago
American Airlines
Sun, 24 Aug - Sun, 31 Aug
DSM
Des Moines
SFO
San Francisco
€226 Return, found 1 day ago
€226
Return
found 1 day ago
Select American Airlines flight, departing Sun, 24 Aug from Des Moines to San Francisco, returning Sun, 31 Aug, priced at €226 found 1 day ago
Delta
Sun, 24 Aug - Sun, 31 Aug
DSM
Des Moines
SFO
San Francisco
€262 Return, found 1 day ago
€262
Return
found 1 day ago
Select Delta flight, departing Sun, 24 Aug from Des Moines to San Francisco, returning Sun, 31 Aug, priced at €262 found 1 day ago
American Airlines
Sun, 24 Aug - Sun, 31 Aug
DSM
Des Moines
SFO
San Francisco
€265 Return, found 1 day ago
€265
Return
found 1 day ago
Select American Airlines flight, departing Sun, 24 Aug from Des Moines to San Francisco, returning Sun, 31 Aug, priced at €265 found 1 day ago
Delta
Sun, 24 Aug - Sun, 31 Aug
DSM
Des Moines
SFO
San Francisco
€273 Return, found 1 day ago
€273
Return
found 1 day ago
Select Delta flight, departing Sun, 24 Aug from Des Moines to San Francisco, returning Sun, 31 Aug, priced at €273 found 1 day ago
United
Sun, 24 Aug - Sun, 31 Aug
DSM
Des Moines
SFO
San Francisco
€300 Return, found 1 day ago
€300
Return
found 1 day ago
Select United flight, departing Sun, 24 Aug from Des Moines to San Francisco, returning Sun, 31 Aug, priced at €300 found 1 day ago

Find the cheapest month to fly from Des Moines (DSM) to San Francisco (SFO)

September is typically the cheapest month to fly

From €101 - €364 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.