Cheap flights from Santiago Metropolitan Region starting at €65

View €65 flight on Tue, 23 Dec 2025Opens in a new window

Popular airlines from Santiago Metropolitan Region

  • LATAM Airlines Group

    LATAM Airlines Group

  • Iberia

    Iberia

  • British Airways

    British Airways

  • KLM

    KLM

  • American Airlines

    American Airlines

  • Delta

    Delta

  • Avianca

    Avianca

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 15% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheapest flights from Santiago Metropolitan Region

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Fri, 19 Dec - Sun, 21 Dec
SCL
Santiago
PUQ
Punta Arenas
€129 Return, found 3 days ago
€129
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Fri, 19 Dec from Santiago to Punta Arenas, returning Sun, 21 Dec, priced at €129 found 3 days ago
Aerolineas Argentinas
Fri, 21 Nov - Thu, 27 Nov
SCL
Santiago
AEP
Buenos Aires
€176 Return, found 5 days ago
€176
Return
found 5 days ago
Select Aerolineas Argentinas flight, departing Fri, 21 Nov from Santiago to Buenos Aires, returning Thu, 27 Nov, priced at €176 found 5 days ago
LATAM Airlines Group
Sun, 17 Aug - Sat, 23 Aug
SCL
Santiago
LIM
Lima
€178 Return, found 5 days ago
€178
Return
found 5 days ago
Select LATAM Airlines Group flight, departing Sun, 17 Aug from Santiago to Lima, returning Sat, 23 Aug, priced at €178 found 5 days ago
Aerolineas Argentinas
Sat, 6 Sep - Sun, 7 Sep
SCL
Santiago
EZE
Buenos Aires
€192 Return, found 3 days ago
€192
Return
found 3 days ago
Select Aerolineas Argentinas flight, departing Sat, 6 Sep from Santiago to Buenos Aires, returning Sun, 7 Sep, priced at €192 found 3 days ago
Turkish Airlines
Thu, 7 Aug - Sun, 10 Aug
SCL
Santiago
GRU
Sao Paulo
€249 Return, found 1 day ago
€249
Return
found 1 day ago
Select Turkish Airlines flight, departing Thu, 7 Aug from Santiago to Sao Paulo, returning Sun, 10 Aug, priced at €249 found 1 day ago
KLM
Wed, 5 Nov - Fri, 14 Nov
SCL
Santiago
EZE
Buenos Aires
€257 Return, found 2 days ago
€257
Return
found 2 days ago
Select KLM flight, departing Wed, 5 Nov from Santiago to Buenos Aires, returning Fri, 14 Nov, priced at €257 found 2 days ago
LATAM Airlines Group
Sun, 26 Oct - Thu, 30 Oct
SCL
Santiago
MIA
Miami
€426 Return, found 3 days ago
€426
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Sun, 26 Oct from Santiago to Miami, returning Thu, 30 Oct, priced at €426 found 3 days ago
Delta
Sun, 26 Oct - Thu, 30 Oct
SCL
Santiago
MIA
Miami
€437 Return, found 3 days ago
€437
Return
found 3 days ago
Select Delta flight, departing Sun, 26 Oct from Santiago to Miami, returning Thu, 30 Oct, priced at €437 found 3 days ago
United
Thu, 30 Oct - Sun, 9 Nov
SCL
Santiago
YYZ
Toronto
€440 Return, found 1 day ago
€440
Return
found 1 day ago
Select United flight, departing Thu, 30 Oct from Santiago to Toronto, returning Sun, 9 Nov, priced at €440 found 1 day ago
Copa
Sat, 26 Jul - Fri, 8 Aug
SCL
Santiago
MIA
Miami
€461 Return, found 1 day ago
€461
Return
found 1 day ago
Select Copa flight, departing Sat, 26 Jul from Santiago to Miami, returning Fri, 8 Aug, priced at €461 found 1 day ago
*Available to Expedia members.