Cheap flights from Middlesboro starting at €110

View €110 flight on Sun, 31 Aug 2025Opens in a new window

Popular airlines from Middlesboro

  • American Airlines

    American Airlines

  • United

    United

  • Delta

    Delta

  • Air France

    Air France

  • Aeromexico

    Aeromexico

  • Finnair

    Finnair

  • KLM

    KLM

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 15% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheapest flights from Middlesboro

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, 1 Aug - Mon, 4 Aug
TYS
Knoxville
LGA
New York
€161 Return, found 5 days ago
€161
Return
found 5 days ago
Select American Airlines flight, departing Fri, 1 Aug from Knoxville to New York, returning Mon, 4 Aug, priced at €161 found 5 days ago
Delta
Fri, 1 Aug - Mon, 4 Aug
TYS
Knoxville
LGA
New York
€161 Return, found 5 days ago
€161
Return
found 5 days ago
Select Delta flight, departing Fri, 1 Aug from Knoxville to New York, returning Mon, 4 Aug, priced at €161 found 5 days ago
American Airlines
Sun, 31 Aug - Sun, 7 Sep
TYS
Knoxville
DEN
Denver
€187 Return, just found
€187
Return
just found
Select American Airlines flight, departing Sun, 31 Aug from Knoxville to Denver, returning Sun, 7 Sep, priced at €187 just found
American Airlines
Sun, 31 Aug - Sun, 7 Sep
TYS
Knoxville
DEN
Denver
€204 Return, just found
€204
Return
just found
Select American Airlines flight, departing Sun, 31 Aug from Knoxville to Denver, returning Sun, 7 Sep, priced at €204 just found
Delta
Sun, 31 Aug - Sun, 7 Sep
TYS
Knoxville
DEN
Denver
€219 Return, just found
€219
Return
just found
Select Delta flight, departing Sun, 31 Aug from Knoxville to Denver, returning Sun, 7 Sep, priced at €219 just found
American Airlines
Fri, 1 Aug - Mon, 4 Aug
TYS
Knoxville
LGA
New York
€221 Return, found 5 days ago
€221
Return
found 5 days ago
Select American Airlines flight, departing Fri, 1 Aug from Knoxville to New York, returning Mon, 4 Aug, priced at €221 found 5 days ago
American Airlines
Fri, 1 Aug - Mon, 4 Aug
TYS
Knoxville
LGA
New York
€230 Return, found 5 days ago
€230
Return
found 5 days ago
Select American Airlines flight, departing Fri, 1 Aug from Knoxville to New York, returning Mon, 4 Aug, priced at €230 found 5 days ago
American Airlines
Wed, 30 Jul - Sun, 3 Aug
TYS
Knoxville
LAS
Las Vegas
€234 Return, found 2 days ago
€234
Return
found 2 days ago
Select American Airlines flight, departing Wed, 30 Jul from Knoxville to Las Vegas, returning Sun, 3 Aug, priced at €234 found 2 days ago
Delta
Sun, 31 Aug - Sun, 7 Sep
TYS
Knoxville
DEN
Denver
€237 Return, just found
€237
Return
just found
Select Delta flight, departing Sun, 31 Aug from Knoxville to Denver, returning Sun, 7 Sep, priced at €237 just found
United
Sun, 31 Aug - Sun, 7 Sep
TYS
Knoxville
DEN
Denver
€246 Return, just found
€246
Return
just found
Select United flight, departing Sun, 31 Aug from Knoxville to Denver, returning Sun, 7 Sep, priced at €246 just found

Flights from Middlesboro: Essential Travel Information

Cheapest flight from Middlesboro
€161 (roundtrip)
Best airlines to fly from Middlesboro
American Airlines, Delta, United
Cheapest month to fly from Middlesboro
August
Middlesboro IATA code
TYS
Middlesboro Country/State
Kentucky
Airline ticket deals from Middlesboro
€161 - €246

 

*Available to Expedia members.