Adventure Holidays in Southeast Missouri 2026

Photo by JG Morris

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Hampton Inn Farmington

850 Valley Creek Dr Farmington MO

2 hours drive from Mark Twain National Forest

Stay at this hotel in Farmington. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...

Crown Pointe Lodge, BW Signature Collection

4245 Hunt Rd Farmington MO

2 hours drive from Mark Twain National Forest

Stay at this golf hotel in Farmington. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...

9/10 Wonderful! (683 reviews)

"Arrived at 10 PM it was nice to have a helpful front desk person. Room was clean. However, the l ceiling light just inside the front door is a CFL and very dim the first 10 minutes. Same for the bathroom sconces on each side of the mirror. The light bulbs in two light fixtures between the beds, we’re ..."

Reviewed on 1 Oct 2026

Echo Bluff State Park

34489 Echo Bluff Dr Eminence MO

43 min drive from Mark Twain National Forest

Stay at this business-friendly hotel in Eminence. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Popular attractions Echo Bluff State Park and Current ...

See all 687 properties in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.