DEG7A9 Bald cypress forest in autumn at the Cuddo Unit of the Santee Refuge, SC.

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Our top choices for Orangeburg County hotels

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,465 reviews)
"Great overnight stop"
United States
Gary
The price is €72
includes taxes & fees
15 Jun - 16 Jun
Baymont by Wyndham Santee

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (853 reviews)
"The room was very clean and the staff were extremely friendly"
United States
Jeffrey
The price is €102
includes taxes & fees
21 Jun - 22 Jun
Tru By Hilton Santee

Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,013 reviews)
"Excellent place to stay"
United States
Bartolo
The price is €109
includes taxes & fees
2 Jul - 3 Jul
Tru by Hilton Orangeburg

Spark by Hilton Orangeburg

Spark by Hilton Orangeburg
2.5 star property
Orangeburg
7.8 out of 10, Good, (1,003 reviews)
"Pet friendly and next door to Cracker Barrel."
United States
Timothy M.
The price is €99
includes taxes & fees
14 Jun - 15 Jun
Spark by Hilton Orangeburg

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,012 reviews)
"Nice hotel stay, excellent staff and accommodations."
United States
Carl
The price is €128
includes taxes & fees
21 Jun - 22 Jun
Fairfield Inn & Suites by Marriott Santee

Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
2.0 star property
Orangeburg
8.2 out of 10, Very good, (1,007 reviews)
"Wonderful stay!"
United States
Joie
The price is €76
includes taxes & fees
14 Jun - 15 Jun
Travelodge by Wyndham Orangeburg

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,008 reviews)
"Great breakfast bar - beautiful location in golf course and easy parking. "
United States
Nicole
The price is €105
includes taxes & fees
21 Jun - 22 Jun
Best Western Plus Santee Inn

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (538 reviews)
"Rooms are clean and staff was super nice and accommodating "
United States
Will
The price is €58
includes taxes & fees
5 Jul - 6 Jul
Quality Inn & Suites Santee I-95

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,007 reviews)
"Nice breakfast, rooms spacious, convenient location"
United States
Gloria
The price is €116
includes taxes & fees
21 Jun - 22 Jun
Hampton Inn Santee-I-95

SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (766 reviews)
"Great location, spacious rooms, amazing breakfast."
United States
Pamela
The price is €109
includes taxes & fees
21 Jun - 22 Jun
SpringHill Suites by Marriott Orangeburg

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,010 reviews)
"Clean rooms that were connecting which we requested. Friendly staff. Good breakfast. Met all our needs while traveling with six children."
United States
Leah
The price is €98
includes taxes & fees
28 Jun - 29 Jun
Comfort Inn & Suites Santee

Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very good, (783 reviews)
"Great stay!!"
United States
Laylany
The price is €111
includes taxes & fees
15 Jun - 16 Jun
Fairfield Inn by Marriott Orangeburg

Holiday Inn Express & Suites Orangeburg by IHG

Holiday Inn Express & Suites Orangeburg by IHG
2.5 star property
Orangeburg
8.6 out of 10, Excellent, (832 reviews)
"Love the staff! Very welcoming. Best breakfast."
United States
Beverly
The price is €122
includes taxes & fees
5 Jul - 6 Jul
Holiday Inn Express & Suites Orangeburg by IHG

Quality Inn & Suites Orangeburg

Quality Inn & Suites Orangeburg
2.5 star property
Orangeburg
6.2 out of 10, (671 reviews)
"Clean room the staffs was very professional"
United States
Curtis
The price is €58
includes taxes & fees
12 Jul - 13 Jul
Quality Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (806 reviews)
"The stay was great."
United States
Brandon
The price is €125
includes taxes & fees
5 Jul - 6 Jul
Hampton Inn & Suites Orangeburg

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very good, (1,000 reviews)
"Room was super clean and nice. Convenient location off of 95 and near Santee state park. Only minor complaint is the pool wasn't heated as stated. "
United States
Stefanie
The price is €98
includes taxes & fees
28 Jun - 29 Jun
Holiday Inn Santee by IHG

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (739 reviews)
"Staff was very friendly. "
United States
Sriram
The price is €58
includes taxes & fees
13 Jul - 14 Jul
Travelodge by Wyndham Santee

Baymont by Wyndham Orangeburg North

Baymont by Wyndham Orangeburg North
2.5 star property
Orangeburg
6.0 out of 10, (1,004 reviews)
"Clean rooms enjoyed my stay."
United States
Rontisha
The price is €55
includes taxes & fees
1 Jul - 2 Jul
Baymont by Wyndham Orangeburg North

Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg
2.0 star property
Orangeburg
7.0 out of 10, Good, (990 reviews)
"Clean room. Breakfast good and staff helpful."
United States
Hannah
The price is €57
includes taxes & fees
2 Jul - 3 Jul
Super 8 by Wyndham, Orangeburg

Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (93 reviews)
"Super quaint, quiet, nice little get away."
United States
Karen
The price is €79
includes taxes & fees
15 Jun - 16 Jun
Bells Marina & Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Orangeburg County Hotel Reviews

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Frequently asked questions

How much do hotels in Orangeburg County cost?
Prices for Orangeburg County hotels vary depending on the season and other factors, like Easter and school holidays. You can find cheap options from €55 in a few different ways. Enter your destination and travel dates and then pick your budget using the "Price per night" filter. You can then refine your search by choosing your preferred amenities and more.
When is the best time to go to Orangeburg County?
That all depends on what you want from your trip to Orangeburg County. If you want to visit in summer, which is between June and August, expect average temperatures of between 22ºC and 32ºC. Orangeburg County has a humid subtropical climate, so keep that in mind when packing.
How can I find cheap hotels in Orangeburg County?
The best place to begin your search is with our "Price per night" filter. At the moment, the cheapest properties start at €55 per night. Other ways to grab a budget-friendly Orangeburg County escape are by booking as early as possible and being flexible with the dates you travel. For even more great deals, go to our cheap hotels in Orangeburg County page.
What are the best hotels in Orangeburg County for families?
Pack your bags (and the little ones!) and prepare for an action-packed holiday at one of our top family-friendly hotels in Orangeburg County. Located in Santee, Fairfield Inn & Suites by Marriott Santee is a fabulous pick. Complimentary breakfast and a firepit are among the amenities here. Or kick back with the fam at Hampton Inn Santee-I-95. You can also find your ideal stay by clicking on the "Family friendly" box in the "Traveller experience" section of our handy filters.
Why should I book my Orangeburg County hotel with Expedia?
Expedia is your one-stop shop for planning the ultimate holiday experience in Orangeburg County. You'll find a wide variety of hotels to select from and handy search filters that make it a breeze to find what you're looking for. Worried about your plans changing? Many of our hotels have flexible cancellation policies, because we know flexibility matters. Get more out of your trip with Expedia Rewards. Join for free today to start collecting points and unlocking membership perks. You'll enjoy instant access to Member Prices, which means you can save 10% or more on select hotels!