Uptown - Upper Duval

Key West

Key West Butterfly and Nature Conservatory featuring animals, flowers and zoo animals
Key West Butterfly and Nature Conservatory featuring flowers, zoo animals and animals
South Beach showing a sandy beach and a coastal town as well as a large group of people
South Beach showing a sandy beach, swimming and a luxury hotel or resort
Key West Butterfly and Nature Conservatory showing signage

Popular places to visit

Southernmost Point

Southernmost Point

Snap a memorable photograph from the edge of North America at this monumental landmark.

Southernmost Point
South Beach

South Beach

The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.

South Beach
Key West Butterfly and Nature Conservatory showing food, animals and zoo animals

Key West Butterfly and Nature Conservatory

With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.

Key West Butterfly and Nature Conservatory

Things to do

Aerial view of people snorkeling in Key West

Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast

€43
per adult
92% of travellers recommend
Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast
Aboard the trolley in Key West

Historic Key West Old Town Trolley Hop-On Hop-Off Tour

€47
per adult
86% of travellers recommend
Historic Key West Old Town Trolley Hop-On Hop-Off Tour
12 hours Day at Key West With Boat Tour and Snorkeling

Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar

€23
per adult
80% of travellers recommend
Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar
Miami to Key West Day Trip with Activities

Miami to Key West Day Trip with Activity Options

€33
per adult
82% of travellers recommend
Miami to Key West Day Trip with Activity Options
Florida: Key West Overseas Highway Self-Driving Tour

Florida: Key West Overseas Highway App-Based Driving Audio Tour

€14
per traveller
80% of travellers recommend
Florida: Key West Overseas Highway App-Based Driving Audio Tour
Key West Half-Day Fishing Charter

Key West Half-Day Fishing Charter

€87
per adult
88% of travellers recommend
Key West Half-Day Fishing Charter
See all activities in Key West

Top hotels in Uptown - Upper Duval

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

4 out of 5
1319 Duval Street, Key West, FL
The price is €220 per night from 29 Oct to 30 Oct
€220
29 Oct - 30 Oct
includes taxes & fees
Stay at this 4-star beach hotel in Key West. Enjoy free WiFi, 3 outdoor pools, and a full-service spa. Our guests praise the pool and the bar in our reviews. ...
8.6/10 Excellent! (2,767 reviews)
"I loved the variety of restaurants and the location. It was perfect for my daughter and I, we will be back! Thank you 🤗"

Reviewed on 2 Oct 2025

Southernmost Beach Resort and Guesthouses
Southwinds Motel

Southwinds Motel

2 out of 5
1321 Simonton Street, Key West, FL
The price is €153 per night from 5 Oct to 6 Oct
€153
5 Oct - 6 Oct
includes taxes & fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and a 24-hour front desk. Our guests praise the breakfast and the pool in our reviews. ...
8.6/10 Excellent! (1,189 reviews)
"Hotel is amazing has everything you need. Pools are clean. Service is amazing"

Reviewed on 25 Sept 2025

Southwinds Motel
The Southernmost Inn - Adults Only

The Southernmost Inn - Adults Only

3 out of 5
525 United Street, Key West, FL
The price is €131 per night from 7 Oct to 8 Oct
€131
7 Oct - 8 Oct
includes taxes & fees
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
8.2/10 Very Good! (1,180 reviews)
"Great area, amenities are great"

Reviewed on 28 Sept 2025

The Southernmost Inn - Adults Only
The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton

4 out of 5
1435 Simonton Street, Key West, FL
Fully refundableReserve now, pay when you stay
The price is €233 per night from 14 Oct to 15 Oct
€233
14 Oct - 15 Oct
includes taxes & fees
Stay at this 4-star beach resort in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.4/10 Very Good! (1,020 reviews)
"Great customer service!!"

Reviewed on 29 Sept 2025

The Reach Key West, Curio Collection by Hilton
Santa Maria Suites

Santa Maria Suites

4 out of 5
1401 Simonton St, Key West, FL
The price is €274 per night from 8 Oct to 9 Oct
€274
8 Oct - 9 Oct
includes taxes & fees
Stay at this 4-star resort in Key West. Enjoy free WiFi, 2 outdoor pools, and a fitness center. Our guests praise the pool and the helpful staff in our reviews. ...
9.6/10 Exceptional! (1,008 reviews)
"The room was amazing. We had a balcony that overlooked the pool. The staff are helpful and sincere. They bring fresh muffins daily to your room. We walked everywhere. There is a beach close by. I am a light sleeper and I slept well."

Reviewed on 27 Sept 2025

Santa Maria Suites
Kona Kai Oasis

Kona Kai Oasis

3 out of 5
630 South Street, Key West, FL
Stay at this 3-star guesthouse in Key West. Enjoy free WiFi, free parking, and a garden. Our guests praise the helpful staff in our reviews. Popular attractions ...
8/10 Very Good! (559 reviews)
"Yes plenty of shops near by and not sure about pets"

Reviewed on 30 Sept 2025

Get rates
Kona Kai Oasis
See all 2,799 properties in Uptown - Upper Duval
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown - Upper Duval

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Old Town Key West

5/5(6 area reviews)

While visiting Old Town Key West, you might make a stop by sights like Duval Street and Saint Mary Star of the Sea.

Old Town Key West
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Downtown Key West

While visiting Downtown Key West, you might make a stop by sights like Duval Street and Ernest Hemingway Home and Museum.

Downtown Key West
Harry S. Truman Little White House showing a house and cycling

Bahama Village

5/5(1 area review)

Bahama Village is noteworthy for its historical sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.

Bahama Village
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Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Key West AIDS Memorial.

Casa Marina
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Key West Historic District

4.5/5(66 area reviews)

Travellers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to stop by Duval Street and Saint Mary Star of the Sea.

Key West Historic District
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White Street Gallery District

If you're looking for some top things to see and do in White Street Gallery District and surrounding area, you can visit Duval Street and Saint Mary Star of the Sea.

White Street Gallery District

Uptown - Upper Duval

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