Uptown - Upper Duval
Key West
Visit Uptown - Upper Duval
Popular places to visit
Southernmost Point
Snap a memorable photograph from the edge of North America at this monumental landmark.
South Beach
The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.
Key West Butterfly and Nature Conservatory
With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.
Things to do
Historic Key West Old Town Trolley Hop-On Hop-Off Tour
Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast
Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar
Florida: Key West Overseas Highway App-Based Driving Audio Tour
Mel Fisher Maritime Museum Admission Ticket
Key West Half-Day Fishing Charter
Top hotels in Uptown - Upper Duval
Southernmost Beach Resort and Guesthouses
The best
Reviewed on 8 Jan 2026
The Reach Key West, Curio Collection by Hilton
All was good but never did receive a TV guide which I asked for several times, room service did not replace empty wash gel and hand lotion for 2 days and none of the major channels on the TV, CBS, NBS or ABC???
Reviewed on 8 Jan 2026
The Southernmost Inn - Adults Only
The breakfast and the room cleanliness were exceptional. Well maintained facilities and very nice staff except for the registration on Saturday evening.
Reviewed on 9 Jan 2026
Southwinds Motel
Check-in staff was kind and friendly. We arrived at the hotel earlier and they accommodated an early check in as there was a room ready.
Reviewed on 8 Jan 2026
Douglas House
Room was outfitted with everything one could ask for. Location was perfect for a stay on Key West! Staff was incredibly helpful ! Can’t say enough positive things during our stay.
Reviewed on 9 Jan 2026
Southernmost House
What a gorgeous property, the mansion is gorgeous and the views were awesome. It was so nice to walk out of the property and enjoy all that Duvall street has to offer without ever needing our car.
Reviewed on 29 Dec 2025
Other neighbourhoods around Uptown - Upper Duval
Old Town Key West
While visiting Old Town Key West, you might make a stop by sights like Duval Street and Ernest Hemingway Home and Museum.
Bahama Village
Bahama Village is noteworthy for its historical sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.
Downtown Key West
While visiting Downtown Key West, you might make a stop by sights like Duval Street and Ernest Hemingway Home and Museum.
Key West Historic District
Travellers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to stop by Duval Street and Key West Cemetery.
Casa Marina
While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.
White Street Gallery District
If you're looking for some top things to see and do in White Street Gallery District and surrounding area, you can visit Duval Street and Clarence S. Higgs Memorial Beach Park.
