Uptown - Upper Duval
Key West
Visit Uptown - Upper Duval
Stay near popular Uptown - Upper Duval attractions
Things to do
Key West Morning Snorkel Adventure with Bottomless Mimosas & Breakfast
€39
per adult
94% of travellers recommend
Day trip to Paradise from Miami: Key West Tour with Snorkeling, Open bar
€24
per adult
90% of travellers recommend
Historic Key West Old Town Trolley Hop-On Hop-Off Tour
€48
per adult
88% of travellers recommend
Shark and Wildlife Viewing Adventure in Key West
€85
per adult
100% of travellers recommend
Key West Haunted Tour : Ghosts & Gravestones
€35
per adult
88% of travellers recommend
Key West Dolphin & Snorkeling Tour - Small Group
€105
per adult
100% of travellers recommend
Top hotels in Uptown - Upper Duval
Southernmost Beach Resort and Guesthouses
1319 Duval Street Key West FL
The price is €243 per night from 19 Jul to 20 Jul
€243
19 Jul - 20 Jul
includes taxes & fees
Stay at this beach hotel in Key West. Enjoy free Wi-Fi, 3 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
8.8/10 Excellent! (3,446 reviews)
"My oceanfront room with a balcony was ocean view with a shared balcony! Do not pay for a balcony unless you verify it isn’t shared! The bathroom had mold around the top of the door and the room smelt of mildew. The sargassum smell right now is terrible, so be aware. We used the pool for a very short ..."
Reviewed on 11 Jul 2026
The Reach Key West, Curio Collection by Hilton
1435 Simonton Street Key West FL
The price is €256 per night from 12 Aug to 13 Aug
€256
12 Aug - 13 Aug
includes taxes & fees
Stay at this beach resort in Key West. Enjoy a full-service spa, a private beach and breakfast (surcharge). Our guests praise the helpful staff and the property ...
8.6/10 Excellent! (1,014 reviews)
"Everything was wonderful except for thee seaweed smell, which Iater on found out, they have the option to clean up. It was a consent smell like an outhouse and yes, it did reach past the hotel beach, swimming pool, court yard, and up to my room that I could smell it whenever I opened my balcony door. ..."
Reviewed on 11 Jul 2026
Southwinds Motel
1321 Simonton Street Key West FL
The price is €162 per night from 4 Aug to 5 Aug
€162
4 Aug - 5 Aug
includes taxes & fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools and parking (surcharge). Our guests praise the breakfast and the pool in their reviews. ...
8.6/10 Excellent! (1,361 reviews)
"We spent a long weekend at this hotel for my birthday. The room was nice and cold and the location was great. We especially liked the bar next-door and the Cuban restaurant across the street."
Reviewed on 11 Jul 2026
The Southernmost Inn - Adults Only
525 United Street Key West FL
The price is €160 per night from 19 Jul to 20 Jul
€160
19 Jul - 20 Jul
includes taxes & fees
Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools and parking (surcharge). Our guests praise the breakfast and the pool in their reviews. ...
8.4/10 Very good! (1,412 reviews)
"Our overall stay was amazing! Peaceful and friendly staff! Highly recommended’"
Reviewed on 10 Jul 2026
Douglas House - Adults Only
419 Amelia St Key West FL
The price is €143 per night from 16 Jul to 17 Jul
€143
16 Jul - 17 Jul
includes taxes & fees
Stay at this guesthouse in Key West. Enjoy free Wi-Fi, daily housekeeping and a garden. Popular attractions Southernmost Point and Duval Street are located ...
9.6/10 Exceptional! (445 reviews)
"Hamza and Jen at the front desk were very knowledgeable, efficient and so friendly! The room was clean and there was a system as most hotels have for room service to clean. Temperature was good with AC and ceiling fans to cool the room. We were able to rent a golf cart directly through the hotel, ..."
Reviewed on 10 Jul 2026
Santa Maria Suites
1401 Simonton St Key West FL
The price is €364 per night from 15 Jul to 16 Jul
€364
15 Jul - 16 Jul
includes taxes & fees
Stay at this resort in Key West. Enjoy free Wi-Fi, 2 outdoor pools and a fitness centre. Our guests praise the pool and the helpful staff in their reviews. Popular ...
9.6/10 Exceptional! (1,006 reviews)
"The rooms were very nice and equipped."
Reviewed on 10 Jul 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Uptown - Upper Duval
Find the best Uptown - Upper Duval areas for the activities you enjoy most.
Old Town Key West
While visiting Old Town Key West, you might make a stop by sights like Duval Street and Southernmost Point.
Key West Historic District
Travellers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to stop by Duval Street and Florida Keys Beaches.
Downtown Key West
While visiting Downtown Key West, you might make a stop by sights like Duval Street and Ernest Hemingway Home and Museum.
New Town
While there might not be top attractions in New Town, you can explore the larger area and discover places like Smathers Beach and Key West Tropical Forest and Botanical Garden.
