Phoenix Hotel Guide - Mayo Clinic Scottsdale hotels in Phoenix, United States of America.

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25 Dec - 26 Dec
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26 Dec - 27 Dec
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26 Dec - 28 Dec
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2 Jan - 4 Jan

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Our top choices for Mayo Clinic Scottsdale hotels

Mountain view
Inn at Eagle Mountain

Inn at Eagle Mountain

Inn at Eagle Mountain
3.5 star property
3.1 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (1002)
"Great place to stay. "
United States
Alexandra
The price is €189
includes taxes & fees
18 Jan - 19 Jan 2026
Inn at Eagle Mountain
Lobby lounge
Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
0.3 km from Mayo Clinic Scottsdale
8.2 out of 10, Very good, (1065)
"Beautiful room, couteous and experienced front desk staff. Easiest check in."
United States
April
The price is €101
includes taxes & fees
5 Jan - 6 Jan 2026
Sonesta Select Scottsdale at Mayo Clinic Campus
Suite, 2 Bedrooms, Kitchen
Staybridge Suites Scottsdale - Talking Stick by IHG

Staybridge Suites Scottsdale - Talking Stick by IHG

Staybridge Suites Scottsdale - Talking Stick by IHG
3.0 star property
9.7 km from Mayo Clinic Scottsdale
9.4 out of 10, Exceptional, (964)
"Great stay and staff was awesome!"
United States
Javier
The price is €114
includes taxes & fees
4 Jan - 5 Jan 2026
Staybridge Suites Scottsdale - Talking Stick by IHG
Outdoor pool, open 6:00 AM to 10:00 PM, pool cabanas (surcharge)
Hilton North Scottsdale At Cavasson

Hilton North Scottsdale At Cavasson

Hilton North Scottsdale At Cavasson
4.0 star property
13.4 km from Mayo Clinic Scottsdale
9.6 out of 10, Exceptional, (479)
"Beautiful place… cool location and nice bar and lobby area "
United States
kenneth
The price is €168
includes taxes & fees
3 Jan - 4 Jan 2026
Hilton North Scottsdale At Cavasson
Exterior
Home2 Suites by Hilton Mesa Longbow, AZ

Home2 Suites by Hilton Mesa Longbow, AZ

Home2 Suites by Hilton Mesa Longbow, AZ
4.0 star property
14.8 km from Mayo Clinic Scottsdale
9.6 out of 10, Exceptional, (667)
" Beautiful location and comfortable room. "
United States
debbie
The price is €123
includes taxes & fees
29 Dec - 30 Dec
Home2 Suites by Hilton Mesa Longbow, AZ
Exterior
Talking Stick Resort

Talking Stick Resort

Talking Stick Resort
4.0 star property
8.8 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (4244)
"Staff, location, restaurants, and casino were perfect for our golf trip."
Canada
Sumesh
The price is €176
includes taxes & fees
27 Dec - 28 Dec
Talking Stick Resort
Restaurant
Mountain Shadows Resort Scottsdale

Mountain Shadows Resort Scottsdale

Mountain Shadows Resort Scottsdale
4.5 star property
17 km from Mayo Clinic Scottsdale
9.8 out of 10, Exceptional, (1035)
"Nice hotel"
United States
BRYNN
The price is €313
includes taxes & fees
4 Jan - 5 Jan 2026
Mountain Shadows Resort Scottsdale
Lobby
Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District
2.5 star property
9.6 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (1766)
"The property was easy to find, clean, the beds were comfortable and the free breakfast was good."
United States
Jackie
The price is €94
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Suites Scottsdale Talking Stick Entertainment District
View from property
ADERO Scottsdale Resort, Autograph Collection

ADERO Scottsdale Resort, Autograph Collection

ADERO Scottsdale Resort, Autograph Collection
4.5 star property
3.6 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (911)
"Very clean with beautiful rooms and scenery. "
United States
LaKeisha
The price is €266
includes taxes & fees
8 Jan - 9 Jan 2026
ADERO Scottsdale Resort, Autograph Collection
Outdoor pool, pool cabanas (surcharge)
The Canyon Suites at The Phoenician, Luxury Collection

The Canyon Suites at The Phoenician, Luxury Collection

The Canyon Suites at The Phoenician, Luxury Collection
5.0 star property
Arcadia, 17.4 km from Mayo Clinic Scottsdale
9.8 out of 10, Exceptional, (185)
"Very nice property "
United States
Alfred
The price is €855
includes taxes & fees
7 Jan - 8 Jan 2026
The Canyon Suites at The Phoenician, Luxury Collection
Terrace/patio
Courtyard Scottsdale Salt River

Courtyard Scottsdale Salt River

Courtyard Scottsdale Salt River
3.5 star property
12.2 km from Mayo Clinic Scottsdale
9.4 out of 10, Exceptional, (948)
"The staff was very nice and the location was convenient for us to visit."
United States
Rocky
The price is €114
includes taxes & fees
2 Jan - 3 Jan 2026
Courtyard Scottsdale Salt River
Terrace/patio
Residence Inn Scottsdale Salt River

Residence Inn Scottsdale Salt River

Residence Inn Scottsdale Salt River
3.0 star property
12 km from Mayo Clinic Scottsdale
9.4 out of 10, Exceptional, (252)
"Easy freeway access and staff was friendly"
United States
Heather
The price is €123
includes taxes & fees
2 Jan - 3 Jan 2026
Residence Inn Scottsdale Salt River
Terrace/patio
Wekopa Casino Resort

Wekopa Casino Resort

Wekopa Casino Resort
4.0 star property
10.3 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (1001)
"It was an amazing stay! "
United States
Whitney
Wekopa Casino Resort
Terrace/patio
Hyatt House North Scottsdale

Hyatt House North Scottsdale

Hyatt House North Scottsdale
3.5 star property
14.1 km from Mayo Clinic Scottsdale
9.4 out of 10, Exceptional, (878)
"Great place to stay! Great breakfast and very clean!"
United States
DANICA
The price is €137
includes taxes & fees
31 Dec - 1 Jan 2026
Hyatt House North Scottsdale
Exterior
Home2 Suites by Hilton Scottsdale Salt River

Home2 Suites by Hilton Scottsdale Salt River

Home2 Suites by Hilton Scottsdale Salt River
3.0 star property
9.6 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (578)
"Great stay!"
United States
Chris
The price is €102
includes taxes & fees
11 Jan - 12 Jan 2026
Home2 Suites by Hilton Scottsdale Salt River
Outdoor pool
Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North
3.0 star property
8.7 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (1002)
"We stay there every time we go In Scottsdale."
United States
Andre
The price is €89
includes taxes & fees
4 Jan - 5 Jan 2026
Aiden by Best Western Scottsdale North
Breakfast, lunch and dinner served
Hotel Valley Ho

Hotel Valley Ho

Hotel Valley Ho
4.5 star property
Arts District, 16.6 km from Mayo Clinic Scottsdale
9.6 out of 10, Exceptional, (2159)
"Great place to stay! "
United States
Stephanie
The price is €250
includes taxes & fees
30 Dec - 31 Dec
Hotel Valley Ho
Exterior
Hilton Vacation Club Scottsdale Links Resort

Hilton Vacation Club Scottsdale Links Resort

Hilton Vacation Club Scottsdale Links Resort
3.5 star property
11.3 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (1000)
"Amazing stay! Friendly receptionists, clean and spacious rooms, excellent Jacuzzi and Pools!"
United States
Kathryn
The price is €151
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Vacation Club Scottsdale Links Resort
Courtyard
Hyatt Place North Scottsdale

Hyatt Place North Scottsdale

Hyatt Place North Scottsdale
3.0 star property
14.1 km from Mayo Clinic Scottsdale
9.4 out of 10, Exceptional, (1003)
"Great room, nice view, great food, completely courteous and helpful staff."
United States
Hershel
The price is €114
includes taxes & fees
1 Jan - 2 Jan 2026
Hyatt Place North Scottsdale
Exterior
Four Seasons Resort Scottsdale at Troon North

Four Seasons Resort Scottsdale at Troon North

Four Seasons Resort Scottsdale at Troon North
5.0 star property
Troon North, 17.1 km from Mayo Clinic Scottsdale
9.6 out of 10, Exceptional, (658)
"Grounds are beautiful, particularly the path to Pinnacle Peak Park. Service is excellent in every way including restaurants, bars and room service. Rooms were spacious and clean. "
United States
William
The price is €803
includes taxes & fees
19 Jan - 20 Jan 2026
Four Seasons Resort Scottsdale at Troon North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mayo Clinic Scottsdale Hotel Reviews

ADERO Scottsdale Resort, Autograph Collection

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent
"Spotless room and great staff, the view was amazing as well"
Brianna 2-night trip
Posted 4 days ago
ADERO Scottsdale Resort, Autograph Collection

Hotels near other Mayo Clinic Scottsdale attractions

Eagle Mountain Golf Course

4.4/5 (64 reviews)
Play a round of golf at Eagle Mountain Golf Course and enjoy other activities in Fountain Hills such as running. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Golf Club at Eagle Mountain

4.3/5 (44 reviews)
Play a round of golf at Golf Club at Eagle Mountain and enjoy other activities in Fountain Hills such as running. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?
Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, take a look at the 40 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Mayo Clinic Scottsdale?
Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.
How many hotels will I find close to Mayo Clinic Scottsdale?
Expedia has 40 hotels and other accommodation options within a mile from Mayo Clinic Scottsdale.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?
Yes, most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to get the best deals available near Mayo Clinic Scottsdale.
What can I see and do near Mayo Clinic Scottsdale?
You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, SunRidge Canyon Golf Club or Golf Club at Eagle Mountain are some local sights worth checking out.

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