A large eye sculpture in a park surrounded by trees.

Northeast Missouri Hotel Guide - Hotels with Spa in Northeast Missouri, Missouri

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Check availability on Northeast Missouri Hotels with Spa

Tonight
22 Oct - 23 Oct
Tomorrow
23 Oct - 24 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Northeast Missouri hotels with a spa

A wooden interior with a hot tub, a wheelchair-accessible bench, and a window.
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.
An indoor swimming pool with wooden walls, a tiled floor, and a sign indicating no diving is allowed.
A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.

1. Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
  • Serene spa sanctuary awaits in the heart of Hannibal with rejuvenating hot tub, indoor pool, and hydromassage showers.
€83
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites - Hannibal
A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.
A Holiday Inn hotel with a modern facade, a covered entrance, and landscaped areas with shrubs.
A hotel room with a sofa, armchair, lamp, and a large mirror.
An outdoor patio with tables and chairs, green umbrellas, and string lights.

2. Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
Quincy
  • Revitalising spa treatments await at this hotel, where an indoor pool, cosy pillow menus, and attentive staff create a relaxing retreat.
€113
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Quincy East by IHG
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A room with a green armchair, a round table, a lamp, and a mirror on the wall.
A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.
A room with a bed, a nightstand with a lamp, a painting on the wall, and a radiator.

3. Truitt Hotel

Truitt Hotel
Lafayette Square
€182
includes taxes & fees
28 Oct - 29 Oct
Truitt Hotel
A spa area with a massage table, a hot tub, and a grill.
A living room with a fireplace, a dining area with a round table, and a balcony with a view.
A row of houses with a driveway leading to a gated entrance.
A hot tub, a fire pit, and a view of a lake.

4. Hermann Hill

Hermann Hill
Hermann
  • Riverside bed and breakfast with private hot tubs and spa treatments offers romantic rejuvenation.
€312
includes taxes & fees
2 Nov - 3 Nov
Hermann Hill
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.

5. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
€154
includes taxes & fees
15 Nov - 16 Nov
21C Museum Hotel St Louis
A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A bakery display case with various pastries and cakes.

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
€180
includes taxes & fees
16 Nov - 17 Nov
Ameristar Casino Resort and Spa
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
A couple standing on a balcony with a cityscape view.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.

7. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
€602
includes taxes & fees
1 Nov - 2 Nov
The Ritz-Carlton, St. Louis
A couple relaxing by a window overlooking a bridge and water.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.
A modern hotel lobby with a glass facade, seating area, and a staircase.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.

8. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
€390
includes taxes & fees
1 Nov - 2 Nov
Four Seasons Hotel St Louis
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Choose what matters most at spa hotels in Northeast Missouri

Pool
Breakfast included
Hot tub
4 stars
5 stars

Spa hotels with free breakfast in Northeast Missouri

A hotel room with a bed, a sofa, a desk, and a lamp.
A restaurant with multiple tables and chairs, an exit sign, and a counter area.
A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.
A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.

Comfort Inn & Suites - Hannibal

Comfort Inn & Suites - Hannibal
Hannibal
€83
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites - Hannibal
A modern reception area with a marble counter, a wooden panel with a light fixture, a fireplace, and a seating area with a sofa and chairs.
A Holiday Inn hotel with a modern facade, a covered entrance, and landscaped areas with shrubs.
A hotel room with a sofa, armchair, lamp, and a large mirror.
An outdoor patio with tables and chairs, green umbrellas, and string lights.

Holiday Inn Quincy East by IHG

Holiday Inn Quincy East by IHG
Quincy
€113
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Quincy East by IHG
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A spacious lobby with multiple seating areas, a pool table, and artwork on the walls.
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."

21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
€154
includes taxes & fees
15 Nov - 16 Nov
21C Museum Hotel St Louis
A hot tub, a fire pit, and a view of a lake.
A bathroom with a bathtub, a shower, and a vanity with a mirror.
A hotel room with a large bed, a bathtub, and a view of the outdoors.
A hot tub with a view of a forest, a bath brush, and a robe hanging on the wall.

Hermann Hill

Hermann Hill
Hermann
€312
includes taxes & fees
2 Nov - 3 Nov
Hermann Hill
An outdoor seating area with modern furniture, a bar, and large windows offering views of a cityscape.
A modern living room with a sofa, chairs, a coffee table, and a chandelier.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A bar area with leather seating, a bar counter, and shelves of bottles.

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
€602
includes taxes & fees
1 Nov - 2 Nov
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Northeast Missouri Hotel Reviews

Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent
"Loved the area to the event"
Jorge 3-night trip
Posted 5 hours ago
Pear Tree Inn St. Louis Near Union Station
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

10/10 Excellent
"Room was quite large and very comfortable."
Barbara 3-night trip
Posted 14 hours ago
Ameristar Casino Resort and Spa
Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent
"The staff were friendly and helpful. It was a wonderful stay a around"
Irma 1-night trip
Posted 1 day ago
Drury Plaza Hotel St. Louis Union Station

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