Florence, Italy - Basilica di Santo Spirito, Tuscany religious architecture

Florence Hotel Guide - Piazza Santo Spirito hotels in Florence, Italy.

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Our top choices for Piazza Santo Spirito hotels

SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms
San Frediano, < 0.1 km from Piazza Santo Spirito
10.0 out of 10, Exceptional, (25 reviews)
"Easy check in and very helpful and polite "
United States
Remi
The price is €224
includes taxes & fees
18 Jul - 19 Jul
SPIRIT OF FLORENCE Boutique Rooms

Soprarno Suites

Soprarno Suites
Historic Centre of Florence, 0.1 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (413 reviews)
"The room was lovely and clean, the breakfast was exemplary and the staff were a delight."
United States
Valerie
The price is €310
includes taxes & fees
12 Jul - 13 Jul
Soprarno Suites

Oltrarno Splendid

Oltrarno Splendid
San Frediano, 0.2 km from Piazza Santo Spirito
10.0 out of 10, Exceptional, (123 reviews)
"We absolutely loved our 3-night stay at Oltrarno Splendid - a true hidden Gem in the best location - with cool shopping vibes and on the quieter side of the river! We loved the neighborhood feel and soaring ceilings for an authentice Florence stay with all the modern ammenities. Beautiful breakfast included and exceptionally friendly, helpful staff - shout-outs to Davide & Barbara!"
Canada
Leanne
The price is €274
includes taxes & fees
12 Jul - 13 Jul
Oltrarno Splendid

AdAstra Suites

AdAstra Suites
San Frediano, 0.2 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (231 reviews)
"What a special place! Beautiful place, large room and beautifully garden and comfortable and welcoming gathering/common area space where we were treated like old friends. Cannot wait to return."
United States
Mary Clare
The price is €270
includes taxes & fees
19 Jul - 20 Jul
AdAstra Suites

Borgia di Firenze

Borgia di Firenze
Duomo, 0.5 km from Piazza Santo Spirito
10.0 out of 10, Exceptional, (11 reviews)
"The location is perfect for fashionistas! The staff, Serena and Greta were most gracious and helpful. Centrally located with pleasant furnishings."
United States
David
The price is €188
includes taxes & fees
5 Jul - 6 Jul
Borgia di Firenze

Toscanelli Residenza D'epoca

Toscanelli Residenza D'epoca
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (384 reviews)
"Great staff and location"
United States
Albert
The price is €129
includes taxes & fees
6 Jul - 7 Jul
Toscanelli Residenza D'epoca

Stella d'Italia

Stella d'Italia
4.0 star property
Duomo, 0.6 km from Piazza Santo Spirito
10.0 out of 10, Exceptional, (209 reviews)
"Really great boutique option in Florence and the rooms are incredible! Very chic and spacious and great location as well. Loved it and would stay here again!"
United States
Victoria
The price is €265
includes taxes & fees
25 Jul - 26 Jul
Stella d'Italia

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
San Frediano, 0.5 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (151 reviews)
"We had a very nice stay. Claudia was very friendly and service minded The place serves continental breakfast - and is a good idea to supplement it a little bit! Nice and quiet area, where you can walk to most things We can only recommend it Else Marie Hansen May 2026"
Denmark
Else Marie
The price is €116
includes taxes & fees
5 Jul - 6 Jul
Drom Florence Rooms & Apartments

Casa Botticelli

Casa Botticelli
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (47 reviews)
"Friendly staff and excellent breakfast "
United States
Mingjiang
The price is €303
includes taxes & fees
25 Jun - 26 Jun
Casa Botticelli

B & Beatrice

B & Beatrice
Historic Centre of Florence, 0.1 km from Piazza Santo Spirito
9.4 out of 10, Exceptional, (112 reviews)
"Good location Helpful staff"
United States
maryjo
The price is €110
includes taxes & fees
28 Jun - 29 Jun
B & Beatrice

Palazzo Martellini Residenza d'Epoca

Palazzo Martellini Residenza d'Epoca
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (73 reviews)
"Very nice and so close to all places by walking."
United States
Mary
The price is €239
includes taxes & fees
15 Jul - 16 Jul
Palazzo Martellini Residenza d'Epoca

Numa Florence Palazzo Belfiore

Numa Florence Palazzo Belfiore
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (397 reviews)
"Perfect location for sightseeing but also a bit of distance from all the crowds. Will definitely stay here again!"
Canada
Megan
The price is €268
includes taxes & fees
30 Jun - 1 Jul
Numa Florence Palazzo Belfiore

Residenza Alessandra

Residenza Alessandra
San Giovanni, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (88 reviews)
"Great staff"
United States
Jessica
The price is €168
includes taxes & fees
14 Jul - 15 Jul
Residenza Alessandra

Palazzo D'Oltrarno - Residenza D'Epoca

Palazzo D'Oltrarno - Residenza D'Epoca
San Frediano, 0.3 km from Piazza Santo Spirito
9.4 out of 10, Exceptional, (55 reviews)
"lovely hotel - very nice staff and beautiful rooms. could be a little loud at night but not a problem. excellent location, super convenient"
United Kingdom
Hannah
The price is €183
includes taxes & fees
2 Jul - 3 Jul
Palazzo D'Oltrarno - Residenza D'Epoca

Hotel Milu Florence

Hotel Milu Florence
4.0 star property
San Giovanni, 0.6 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (643 reviews)
"Great stay, thanks Wonderful location and breakfasts were the best!"
United States
Filipe
The price is €321
includes taxes & fees
5 Jul - 6 Jul
Hotel Milu Florence

Portrait Firenze - Lungarno Collection

Portrait Firenze - Lungarno Collection
5.0 star property
San Giovanni, 0.5 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (315 reviews)
"The staff was fantastic. Very helpful. The location is great."
United States
Matthew
The price is €1,501
includes taxes & fees
8 Jul - 9 Jul
Portrait Firenze - Lungarno Collection

Antica Torre di Via Tornabuoni 1

Antica Torre di Via Tornabuoni 1
Duomo, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (593 reviews)
"Clean room, friendly staff, great roof top terrace and bar. Breakfast was nice. Perfect location!"
United States
matthew
The price is €329
includes taxes & fees
6 Jul - 7 Jul
Antica Torre di Via Tornabuoni 1

Leone Blu Suites | UNA Esperienze

Leone Blu Suites | UNA Esperienze
Duomo, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (201 reviews)
"Our second time there.....and we'll absolutely stay again the next time we are in Florence. Bravissimo"
Canada
peter
The price is €281
includes taxes & fees
17 Jul - 18 Jul
Leone Blu Suites | UNA Esperienze

Hotel Lungarno - Lungarno Collection

Hotel Lungarno - Lungarno Collection
5.0 star property
Historic Centre of Florence, 0.4 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (622 reviews)
"We stayed in the Design Suite, it was amazing and a great fit for our family of 5. The staff was amazing as well, always very helpful and kind"
United States
Nathan
The price is €841
includes taxes & fees
13 Jul - 14 Jul
Hotel Lungarno - Lungarno Collection

Tornabuoni Suites Collection

Tornabuoni Suites Collection
Duomo, 0.6 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (308 reviews)
"Excellent location, room, and staff."
United States
Mickey
The price is €217
includes taxes & fees
17 Jul - 18 Jul
Tornabuoni Suites Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Piazza Santo Spirito Hotel Reviews

Hotels near other Piazza Santo Spirito attractions

Frequently asked questions

What's the area like around Piazza Santo Spirito?
Piazza Santo Spirito is located in a historic area of Florence known for its stunning cathedral and popular art scene. If you're looking for a convenient place to stay, take a look at the 3078 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay close to Piazza Santo Spirito?
Adjacent to Piazza Santo Spirito, Hotel La Scaletta Al Ponte Vecchio is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and a bar. Other good choices close by include Hotel Paris and Grand Hotel Baglioni.
How many hotels will I find close to Piazza Santo Spirito?
Expedia has 3078 hotels and other accommodation options within a mile from Piazza Santo Spirito.
If I need to cancel the hotel reservation for my stay near Piazza Santo Spirito, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to get the best deals near Piazza Santo Spirito.
What can I see and do near Piazza Santo Spirito?
Study the collections at Uffizi Gallery, Gucci Museum or Basilica of Santa Maria Novella. Ponte Vecchio, Via Maggio and Pitti Palace are landmarks that you won't want to miss. You can check out the local talent at Visarno Arena, Teatro Comunale Florence and Teatro Verdi.
How can I get to Piazza Santo Spirito?
With so many ways to get around, seeing all of the area near Piazza Santo Spirito is easy. Nearby metro stations include Unità Tram Stop, Valfonda - Stazione Santa Maria Novella Tram Stop and San Marco University Tram Stop. If you're taking a train into town, Florence (ZMS-Santa Maria Novella Train Station) and Florence Santa Maria Novella Station are the closest stops to Historic Centre of Florence.