Aerial view of house in Serra Mesa City in San Diego, California, USA. Green Dry Valley and Villas

San Diego Hotel Guide. Hotels in Serra Mesa, San Diego, United States of America

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Our top choices for Serra Mesa hotels

La Quinta Inn by Wyndham San Diego - Miramar

La Quinta Inn by Wyndham San Diego - Miramar
3.0 star property
16.7 km from Serra Mesa
8.0 out of 10, Very good, (1,324 reviews)
"Clean rooms, helpful staff and great breakfast."
United States
isabel
The price is €130
includes taxes & fees
1 Jul - 2 Jul
La Quinta Inn by Wyndham San Diego - Miramar

Hampton Inn & Suites San Diego Airport Liberty Station

Hampton Inn & Suites San Diego Airport Liberty Station
2.5 star property
10.6 km from Serra Mesa
9.2 out of 10, Wonderful, (1,715 reviews)
"Good location, clean room and nice staff. A great place to stay."
United States
Patricia
The price is €166
includes taxes & fees
30 Jun - 1 Jul
Hampton Inn & Suites San Diego Airport Liberty Station

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
16.1 km from Serra Mesa
9.2 out of 10, Wonderful, (3,893 reviews)
"Great stay"
United States
Cameron
The price is €165
includes taxes & fees
30 Jun - 1 Jul
Best Western Plus Marina Gateway Hotel

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
28.1 km from Serra Mesa
8.8 out of 10, Excellent, (1,312 reviews)
"The breakfast was great, the staff was helpful, and the room was clean and spacious!"
United States
Christopher
The price is €122
includes taxes & fees
5 Jul - 6 Jul
Best Western Americana Inn

Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
4.0 star property
University City, 10.3 km from Serra Mesa
8.8 out of 10, Excellent, (1,942 reviews)
"Great location and very comfortable and spacious hotel room"
United States
Carmen
The price is €246
includes taxes & fees
5 Jul - 6 Jul
Embassy Suites by Hilton San Diego La Jolla

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.8 km from Serra Mesa
9.4 out of 10, Exceptional, (1,993 reviews)
"Always a great stay"
United States
Jeanette
The price is €122
includes taxes & fees
12 Jul - 13 Jul
Sycuan Casino Resort

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
9 km from Serra Mesa
7.4 out of 10, Good, (4,204 reviews)
"Clean room, staff was very helpful, parking was easy and accessible!"
United States
Hector
The price is €130
includes taxes & fees
1 Jul - 2 Jul
Wyndham Garden San Diego Near SeaWorld

Comfort Inn Chula Vista San Diego South

Comfort Inn Chula Vista San Diego South
2.5 star property
18.6 km from Serra Mesa
8.2 out of 10, Very good, (1,561 reviews)
"The room was comfortable and conveniently located. Breakfast was great for the cost of our stay."
United States
Arsenia P
The price is €122
includes taxes & fees
19 Jul - 20 Jul
Comfort Inn Chula Vista San Diego South

SpringHill Suites by Marriott San Diego Rancho Bernardo/Scripps Poway

SpringHill Suites by Marriott San Diego Rancho Bernardo/Scripps Poway
3.0 star property
15.2 km from Serra Mesa
8.8 out of 10, Excellent, (1,222 reviews)
"Clean room, a good breakfast and aa safe palce to stay in with kids"
United States
Lorenz
The price is €181
includes taxes & fees
2 Jul - 3 Jul
SpringHill Suites by Marriott San Diego Rancho Bernardo/Scripps Poway

Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
18.5 km from Serra Mesa
9.4 out of 10, Exceptional, (1,254 reviews)
"We had a very wonderful time at our stay here"
United States
Liezl
The price is €158
includes taxes & fees
7 Jul - 8 Jul
Holiday Inn Express San Diego South - Chula Vista by IHG

Ayres Hotel San Diego South - Chula Vista

Ayres Hotel San Diego South - Chula Vista
3.0 star property
26 km from Serra Mesa
9.8 out of 10, Exceptional, (1,099 reviews)
"Nice place good food for breakfast 👍"
United States
Paul
The price is €204
includes taxes & fees
19 Jul - 20 Jul
Ayres Hotel San Diego South - Chula Vista

Valli Hi Motel

Valli Hi Motel
2.5 star property
28.3 km from Serra Mesa
8.4 out of 10, Very good, (1,023 reviews)
"Great place to stay."
United States
Allan
The price is €90
includes taxes & fees
29 Jun - 30 Jun
Valli Hi Motel

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (2,191 reviews)
"THE BED WAS SO SOFT ROOM WAS SO CLEAN BREAKFAST WAS GREAT AND THE PRICE WAS KILLER FOR THE LOCATION really a great place to stay"
United States
Tyson
The price is €162
includes taxes & fees
1 Jul - 2 Jul
GreenTree Inn San Diego Mission Bay

Best Western Plus Hacienda Hotel Old Town

Best Western Plus Hacienda Hotel Old Town
3.0 star property
Old Town San Diego, 7.6 km from Serra Mesa
8.4 out of 10, Very good, (2,056 reviews)
"Excellent stay! Beautiful grounds and friendly staff."
United States
Rebecca
The price is €160
includes taxes & fees
2 Jul - 3 Jul
Best Western Plus Hacienda Hotel Old Town

Hampton Inn San Diego-Kearny Mesa

Hampton Inn San Diego-Kearny Mesa
2.5 star property
3.5 km from Serra Mesa
9.2 out of 10, Wonderful, (1,002 reviews)
The price is €161
includes taxes & fees
30 Jun - 1 Jul
Hampton Inn San Diego-Kearny Mesa

Days Inn by Wyndham San Diego-East/El Cajon

Days Inn by Wyndham San Diego-East/El Cajon
2.0 star property
17.7 km from Serra Mesa
7.8 out of 10, Good, (1,001 reviews)
"Rooms were cheap clean property was clean convenient close to where I was working"
United States
James
The price is €111
includes taxes & fees
12 Jul - 13 Jul
Days Inn by Wyndham San Diego-East/El Cajon

Country Inn & Suites by Radisson, San Diego North, CA

Country Inn & Suites by Radisson, San Diego North, CA
3.0 star property
11.7 km from Serra Mesa
9.0 out of 10, Wonderful, (1,544 reviews)
"Very great stay"
United States
Phillip
The price is €188
includes taxes & fees
6 Jul - 7 Jul
Country Inn & Suites by Radisson, San Diego North, CA

Homewood Suites by Hilton San Diego Airport/Liberty Station

Homewood Suites by Hilton San Diego Airport/Liberty Station
3.0 star property
10.9 km from Serra Mesa
9.4 out of 10, Exceptional, (1,547 reviews)
"Great stay, everything was outstanding"
United States
Bill
The price is €220
includes taxes & fees
8 Jul - 9 Jul
Homewood Suites by Hilton San Diego Airport/Liberty Station

HYATT house San Diego/Sorrento Mesa

HYATT house San Diego/Sorrento Mesa
3.0 star property
11.8 km from Serra Mesa
9.2 out of 10, Wonderful, (1,006 reviews)
"Amazing stay"
United States
Kevin
The price is €214
includes taxes & fees
5 Jul - 6 Jul
HYATT house San Diego/Sorrento Mesa

California Suites Hotel

California Suites Hotel
2.0 star property
4.8 km from Serra Mesa
7.8 out of 10, Good, (2,664 reviews)
"Had a wonderful stay. Would stay here again"
United States
Ariana
The price is €109
includes taxes & fees
28 Jun - 29 Jun
California Suites Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Top Serra Mesa Hotel Reviews

Find out more about Serra Mesa

Top reasons to visit Serra Mesa

  • Outdoor Recreation: Serra Mesa boasts numerous parks and outdoor spaces, perfect for family outings and fun activities.
  • Cultural Experiences: Immerse yourself in the area's rich history and local culture while enjoying its scenic beauty.
  • Diverse Activities: From dolphin cruises to shopping centres, Serra Mesa offers a wide range of activities for all ages.
  • Family-Friendly Atmosphere: The neighbourhood is ideal for families, providing safe and engaging experiences for children.
  • Convenient Location: Serra Mesa serves as a great base for exploring the vibrant city of San Diego and its stunning beaches.

Find great hotels near Serra Mesa

Discover a delightful range of accommodation options in Serra Mesa, San Diego, perfect for every type of traveller. Whether you're seeking pet-friendly hotels, spacious apartments, or charming vacation homes, you'll find a variety of choices to enhance your stay. With its convenient location, Serra Mesa offers a family-friendly atmosphere and plenty of adventure opportunities, ensuring an enjoyable experience for all visitors.

  • California Suites Hotel: California Suites Hotel offers an economical lodging experience ideal for business travellers seeking convenience and comfort. Located 4.8km from Serra Mesa, this budget-friendly hotel features essential amenities such as complimentary Wi-Fi, a business centre, and meeting spaces. Guests appreciate the straightforward accommodations that provide a homely atmosphere with basic kitchen facilities in select rooms, allowing for a flexible stay. The hotel’s proximity to business districts makes it a practical choice for professionals visiting the area.
  • Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area: This 3-star hotel is a family-friendly haven, located 6.4km from Serra Mesa. With a commendable guest rating of 8.8 out of 10, it caters to families and pet owners alike. The hotel boasts spacious suites equipped with kitchenettes, making it easy for families to prepare meals. Children’s amenities, including a games room and a ping pong table, ensure entertainment for younger guests. Additionally, pets are warmly welcomed, with dedicated facilities and services, ensuring a comfortable stay for the entire family.
  • San Diego Mission Bay Resort: A luxurious 4-star option, San Diego Mission Bay Resort is situated 8.0km from Serra Mesa and offers a blend of relaxation and adventure. With a guest rating of 8.4 out of 10, this resort features direct beach access, allowing guests to indulge in sun-soaked days and water sports. Exciting activities such as windsurfing, motorboating, and hiking nearby provide ample opportunities for adventure enthusiasts. The resort’s lush surroundings and top-notch amenities make it a perfect retreat for those looking to unwind by the beach while enjoying thrilling experiences.

Where to stay near Serra Mesa

Serra Mesa, a charming neighbourhood in San Diego, offers a delightful blend of family-friendly activities and outdoor adventures. Stroll through its tranquil parks or explore nearby attractions that showcase the area's rich history and welcoming atmosphere. Just a short drive away, you can discover the vibrant culture of San Diego, with its stunning beaches and bustling city life. Whether you're seeking relaxation or excursions, Serra Mesa is the perfect base for your Californian holiday.

  • University Heights: Nestled approximately 4.8km from Serra Mesa, University Heights is a vibrant neighbourhood known for its eclectic charm. The area attracts visitors year-round, with peaks in March, July, and September. It offers a delightful blend of family-friendly outdoor activities and urban experiences. Wander through its quaint streets to discover educational institutions, local shopping centres, and inviting parks. Notable attractions include a modern college campus and the scenic beauty of nearby beaches and bays, making it a perfect spot for both relaxation and exploration.
  • North Park: Located around 6.4km from Serra Mesa, North Park is a lively neighbourhood celebrated for its artistic flair and diverse culture. With a steady influx of visitors, especially during March to April and July, it boasts a myriad of outdoor activities and family-oriented attractions. Experience the local scene through its unique shopping centres and historic sites, or enjoy leisurely strolls in urban parks. North Park is a hub for creativity, offering a vibrant atmosphere that reflects the spirit of San Diego.
  • Middletown: Situated 8.0km from Serra Mesa, Middletown is a charming neighbourhood that combines the best of outdoor living and beachside relaxation. This area sees consistent visitor numbers, with a notable increase in March and during the summer months. Travellers flock here for its family-friendly recreational areas and proximity to stunning beaches. Explore local shopping centres and enjoy events at the nearby convention centre, all while soaking in the inviting coastal vibe that Middletown has to offer.

Things to do near Serra Mesa

Shopping

In Serra Mesa, you can explore the Fashion Valley Mall for a variety of high-end and popular brands. For a more local feel, visit the Serra Mesa Community Market, where you'll discover unique crafts and artisanal goods, perfect for meaningful gifts and souvenirs.

Recreation

Serra Mesa offers the tranquil Oasis Day Spa, where you can indulge in rejuvenating treatments and holistic therapies. Nearby, the scenic Mission Trails Regional Park invites you to explore its scenic hiking paths, ideal for unwinding amidst nature’s beauty and enjoying the fresh Californian air.

Adventure

At Barona Speedway, located 35.4km from Serra Mesa, you can immerse yourself in the thrilling world of motor racing. Experience the adrenaline rush as you watch high-speed races and feel the excitement of the track, all amidst a lively atmosphere perfect for adventure enthusiasts.

Nightlife

Explore the vibrant nightlife at The Seven Seas Cafe, where you can enjoy a relaxed atmosphere with craft cocktails. For a lively evening, visit the nearby The Royale Lounge for a mix of dancing and live music, making it a popular choice among locals.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Serra Mesa

Serra Mesa is an ideal destination for family outings and outdoor adventures, offering a mix of urban parks, private gardens, and scenic bays. Visitors can immerse themselves in cultural experiences while enjoying the area’s natural beauty. With various attractions nearby, Serra Mesa caters to those seeking diverse activities, making it a perfect spot for a memorable holiday.

  • Mission Bay: Located 8.0km from Serra Mesa, Mission Bay is a stunning waterfront area renowned for its beautiful beaches and scenic views. Visitors can enjoy a variety of outdoor activities, from sunbathing and picnicking to water sports like kayaking and paddleboarding, all set against a picturesque backdrop.
  • Balboa Park: Also 8.0km away, Balboa Park is a magnificent urban oasis that features beautifully landscaped gardens, cultural institutions, and stunning architecture. This sprawling park is ideal for leisurely strolls, offering a serene atmosphere to appreciate nature and art alike.
  • Hotel Circle: Situated 4.8km from Serra Mesa, Hotel Circle is a vibrant street lined with a variety of accommodations, dining options, and shops. This area exudes a lively city vibe, making it a convenient base for exploring San Diego's attractions.

Best time to go to Serra Mesa

The best time to visit Serra Mesa can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Serra Mesa falls in August, when visitor numbers are average and weather is sunny with no rain. The coolest average temperature around Serra Mesa falls in February, visitor numbers are average and weather is sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January57.4°F (14.1°C)Light RainSunnyModerately LowSlightly Low
February56.8°F (13.8°C)Light RainSunnyAverageAverage
March58.1°F (14.5°C)No RainMostly SunnyModerately HighAverage
April60.6°F (15.9°C)No RainSunnyAverageAverage
May62.6°F (17.0°C)No RainSunnyAverageAverage
June66.4°F (19.1°C)No RainSunnyModerately HighSlightly High
July70.5°F (21.4°C)No RainSunnyModerately HighSlightly High
August72.3°F (22.4°C)No RainSunnyAverageSlightly High
September72.0°F (22.2°C)No RainSunnyAverageAverage
October68.2°F (20.1°C)No RainSunnyModerately LowAverage
November62.6°F (17.0°C)No RainSunnyModerately LowSlightly Low
December57.4°F (14.1°C)Light RainMostly SunnyAverageSlightly Low

The nearest major airports for your trip to Serra Mesa

Flying into Serra Mesa is convenient, with San Diego International Airport (SAN) located 9.7km away. Recommended hotels nearby include the 4-star Hard Rock Hotel San Diego and DoubleTree by Hilton Hotel San Diego - Mission Valley, both 4.8km from the airport. For those considering alternative airports, John Wayne Airport (SNA) is 119.1km away, with the 4-star Renaissance Newport Beach Hotel just 1.3km from there. Lastly, Ontario International Airport (ONT) is 146.4km from Serra Mesa, with the 3-star Hyatt Place Ontario / Rancho Cucamonga located 4.8km away, providing easy access to the airport.

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 38 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Sharp Learning Resource Center and Convoy District are also worth a stop.

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