Downtown South San Francisco

San Francisco

Photo by Catherine Edejer-McCormick

Popular places to visit

Things to do


Top hotels in Downtown South San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd, South San Francisco, CA
The price is €127 per night from 1 Sept to 2 Sept
€127
1 Sept - 2 Sept
includes taxes & fees
Stay at this 3-star business-friendly hotel in South San Francisco. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast ...
8/10 Very Good! (2,020 reviews)
"I think everything was fine - except we had to go down everyday for new key cards - they stopped working and we picked this hotel because of pool and was closed for maintenance - wish I knew before"

Reviewed on 20 Aug 2025

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St, San Francisco, CA
The price is €150 per night from 25 Aug to 26 Aug
€150
25 Aug - 26 Aug
includes taxes & fees
Book a stay at this eco-certified hotel in San Francisco. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (6,687 reviews)
"Very clean"

Reviewed on 21 Aug 2025

Hotel Riu Plaza Fisherman's Wharf
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center, San Francisco, CA
The price is €221 per night from 28 Aug to 29 Aug
€221
28 Aug - 29 Aug
includes taxes & fees
Stay at this 4-star eco-certified hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (1,809 reviews)
"Good location and very beautiful lobby"

Reviewed on 19 Aug 2025

Hyatt Regency San Francisco
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave, San Francisco, CA
The price is €120 per night from 25 Aug to 26 Aug
€120
25 Aug - 26 Aug
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the pool ...
8.8/10 Excellent! (4,434 reviews)
"The room was clean, spacious and quiet. The lobby was inviting and comfortable. The staff was friendly and welcoming."

Reviewed on 21 Aug 2025

Holiday Inn Golden Gateway by IHG
Crowne Plaza San Francisco Airport by IHG

Crowne Plaza San Francisco Airport by IHG

3.5 out of 5
1177 Airport Blvd, Burlingame, CA
Fully refundable
The price is €99 per night from 31 Aug to 1 Sept
€99
31 Aug - 1 Sept
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in Burlingame. Enjoy free WiFi, room service, and a fitness center. Our guests praise the helpful staff and the ...
7.6/10 Good! (2,053 reviews)
"Great experience"

Reviewed on 19 Aug 2025

Crowne Plaza San Francisco Airport by IHG
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St, San Francisco, CA
The price is €113 per night from 24 Aug to 25 Aug
€113
24 Aug - 25 Aug
includes taxes & fees
Book a stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness center, and WiFi (surcharge). Our guests praise the helpful ...
8.6/10 Excellent! (1,651 reviews)
"The property was great."

Reviewed on 21 Aug 2025

Hilton San Francisco Financial District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Downtown South San Francisco

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Noe Valley

Appreciated for its churches and architecture, you might consider exploring Noe Valley. Check out the variety of things to see and do like 22nd St Hill, and jump on the metro at Church St & Clipper St Stop or Church St & 24th St Stop to get around the city.

Noe Valley
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Mission District

3.5/5(11 area reviews)

You might enjoy the bars while in Mission District. San Francisco Public Library is a notable sight, and you can get around town at 16th Street Mission Station or 24th Street Mission Station to see more of the city.

Mission District
Ocean Beach which includes general coastal views, landscape views and a sandy beach

Outer Sunset

When in Outer Sunset and the surrounding area, you'll want to check out sights like Ocean Beach or San Francisco Botanical Garden and hop on the metro to see more of the city at Judah St & 34th Ave Stop or Judah Street & Sunset Boulevard Station.

Outer Sunset
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Sunset District

3.5/5(6 area reviews)

Consider exploring the beaches in Sunset District. If sightseeing is on the list, Ocean Beach is a top attraction. Hop on the metro at Judah Street & Sunset Boulevard Station or Judah St & 34th Ave Stop to see more of the area.

Sunset District
South of Market which includes cbd, a city and skyline

South of Market

3.5/5(113 area reviews)

Gourmet restaurants great entertainment and top sights from Oracle Park to Chase Center – discover South of Market, a destination also famous for its shopping.

South of Market
California Academy of Sciences featuring interior views as well as a large group of people

Golden Gate

If you're spending time in Golden Gate, check out sights like San Francisco Botanical Garden or Japanese Tea Garden and hop on the metro to see more of the city at Irving St & 9th Ave Stop or Irving St & 8th Ave Stop.

Golden Gate

Downtown South San Francisco

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