Downtown South San Francisco

San Francisco

Aerial View of a Local High School and an Athletic Field in a Neighborhood in South San Francisco, California, USA
Aerial view of the South San Francisco area
Aerial view of downtown San Francisco and Financial District sky scrapers flying over South San Francisco The Industrial City inscription on San Bruno mountain circa 2015

Popular places to visit

Things to do


Top hotels in Downtown South San Francisco

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd South San Francisco CA
The price is €121 per night from 29 Jun to 30 Jun
€121
29 Jun - 30 Jun
includes taxes & fees
Stay at this business-friendly hotel in South San Francisco. Enjoy free breakfast, free Wi-Fi and a free airport shuttle. Our guests praise the breakfast and ...
8.2/10 Very good! (2,015 reviews)
"The hot breakfast was very nice it consisted of eggs some type of meat there were hash browns as well as cereal and waffle maker I will say that the front desk staff was more than helpful there is a lovely middle-aged Hispanic lady who works the front desk on the weekdays during the mornings she ..."

Reviewed on 23 Jun 2026

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
The price is €245 per night from 12 Jul to 13 Jul
€245
12 Jul - 13 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the ...
9.2/10 Wonderful! (2,312 reviews)
"It's bay facing but lot of buildings nearby as well. Location is great overall, course to restaurants, the pier and a Safeway toom"

Reviewed on 23 Jun 2026

Hyatt Regency San Francisco
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
The price is €148 per night from 13 Jul to 14 Jul
€148
13 Jul - 14 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour fitness centre. Our guests praise the pool and the ...
9/10 Wonderful! (5,891 reviews)
"They didn’t give us extra blankets"

Reviewed on 23 Jun 2026

Holiday Inn Golden Gateway by IHG
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
The price is €141 per night from 12 Jul to 13 Jul
€141
12 Jul - 13 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy breakfast (surcharge), a fitness centre and Wi-Fi (surcharge). Our guests praise the helpful staff ...
Hilton San Francisco Financial District
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
The price is €190 per night from 5 Jul to 6 Jul
€190
5 Jul - 6 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the ...
9/10 Wonderful! (7,523 reviews)
"Great place to stay!"

Reviewed on 23 Jun 2026

Hotel Riu Plaza Fisherman's Wharf
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
The price is €189 per night from 2 Jul to 3 Jul
€189
2 Jul - 3 Jul
includes taxes & fees
Stay at this business-friendly hotel in San Francisco. Enjoy free Wi-Fi, a fitness centre and valet parking (surcharge). Our guests praise the pool and the helpful ...
8.8/10 Excellent! (3,238 reviews)
"Good staff outdated"

Reviewed on 23 Jun 2026

Handlery Union Square Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas for the activities you enjoy most.

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.

Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to Chase Center – discover South of Market, a destination also famous for its shopping.

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.



Downtown South San Francisco

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