Sant' Ambrogio Holidays

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    Save up to €900 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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Price found within the past 48 hours. Click for updated prices.
  • Premium bedding, in-room safe, free cots/infant beds, free WiFi
    Jul 22 - Jul 27

    Aurum Uffizi + Flight

    Historic Centre of Florence
    4 nights
    4.0 star property
    7.6/10 - Good (1,006 reviews)
    "Great location. Clean and Comfortable room. Friendly staff. We went out for breakfast even though some fruit etc was available in the morning."
    Reviewed May 21, 2026
    Return • Dublin (DUB) - Florence (FLR)
    DUB - FLR • 1 stop FLR - DUB • 1 stop
    €516
    €307
    per traveller
    found 1 day ago
    Aurum Uffizi
  • Rooftop terrace
    Jul 22 - Jul 27

    Donati Luxury Tower Suites + Flight

    Historic Centre of Florence
    4 nights
    5.0 star property
    9.6/10 - Exceptional (65 reviews)
    "Agradable estancia. Excelente servicio. La habitación la mantenían siempre limpia. Todo queda cerca del área. Muy recomendable"
    Reviewed May 23, 2026
    Return • Dublin (DUB) - Florence (FLR)
    DUB - FLR • 1 stop FLR - DUB • 1 stop
    €1,855
    €1,052
    per traveller
    found 1 day ago
    Donati Luxury Tower Suites
  • Quadruple Room
    Jul 22 - Jul 27

    Aurum Firenze + Flight

    Historic Centre of Florence
    4 nights
    4.0 star property
    7.6/10 - Good (1,006 reviews)
    "The breakfast was not ok coffee machine not working"
    Reviewed May 24, 2026
    Return • Dublin (DUB) - Florence (FLR)
    DUB - FLR • 1 stop FLR - DUB • 1 stop
    €522
    €309
    per traveller
    found 1 day ago
    Aurum Firenze
  • Restaurant
    Jul 22 - Jul 27

    Eurostars Florence Boutique + Flight

    Historic Centre of Florence
    4 nights
    4.0 star property
    8.6/10 - Excellent (487 reviews)
    "The Eurostar F. Boutique's team helped us in any aspect, from moving to a room with a window to help with some plaster for my poor feet. Excellent terrace, great view and well located"
    Reviewed February 24, 2026
    Return • Dublin (DUB) - Florence (FLR)
    DUB - FLR • 1 stop FLR - DUB • 1 stop
    €774
    €488
    per traveller
    found 1 day ago
    Eurostars Florence Boutique
  • Lobby lounge
    Jul 22 - Jul 27

    The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World + Flight

    Historic Centre of Florence
    4 nights
    5.0 star property
    10/10 - Exceptional (18 reviews)
    Return • Dublin (DUB) - Florence (FLR)
    DUB - FLR • 1 stop FLR - DUB • 1 stop
    €2,054
    €1,305
    per traveller
    found 1 day ago
    The James Suite Hotel Firenze 1564 - Small Luxury Hotels of the World

Where to stay in Sant' Ambrogio

Find the best Sant' Ambrogio areas and neighborhoods for the activities you enjoy most. Learn more about Sant' Ambrogio
Historic Centre of Florence

Historic Centre of Florence

10 out of top 10 points of interest in this area

Lose yourself in the Renaissance charm of Florence’s old town, where masterpieces by Brunelleschi and Giotto line up alongside cafés, gelato shops and trattorias.

Find hotels in Historic Centre of Florence

Top hotels in Sant' Ambrogio

Hotel Regency

Hotel Regency

5 out of 5
Piazza M. D'Azeglio, 3 Florence FI
Fully refundableReserve now, pay when you stay
The price is €556 per night from 3 Jun to 4 Jun
€556
3 Jun - 4 Jun
includes taxes & fees
9.4/10 Exceptional! (450 reviews)
"The breakfast was delicious, a wide variety. Service was excellent, quite responsive and attentive staff."

Reviewed on 12 Apr 2026

Hotel Regency
Hotel Bodoni

Hotel Bodoni

2 out of 5
Via Martiri del Popolo, 27 Florence FI
The price is €126 per night from 22 Jun to 23 Jun
€126
22 Jun - 23 Jun
includes taxes & fees
8.2/10 Very Good! (830 reviews)
"A good clean hotel Helpful friendly staff Wonderful location"

Reviewed on 26 May 2026

Hotel Bodoni
Hotel Bavaria

Hotel Bavaria

1 out of 5
Borgo Albizi 26 Florence FI
The price is €127 per night from 8 Jun to 9 Jun
€127
8 Jun - 9 Jun
includes taxes & fees
8.2/10 Very Good! (437 reviews)
"We had an unexpected delay in our travel and arrival and the hotel host was kind enough to allow us to check in at 11:30pm. He was helpful and friendly and we could not have been happier with the check-in process. Thank you!"

Reviewed on 24 May 2026

Hotel Bavaria
See all 530 properties in Sant' Ambrogio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Sant Ambrogio holiday package cost?
Maybe less than you might think — from just , in fact! By combining hotels, flights and car rentals into your own custom-built travel package, your getaway to Sant Ambrogio is only clicks away.
How do I get a cheap travel package to Sant Ambrogio?
Combining your flight and hotel with Expedia won't just save precious time — it'll save you a nice amount too. A Sant Ambrogio holiday package makes it simple to arrange your perfect trip. With more than 550 airlines throughout the world to choose from, finding flights that suit your busy schedule won't be hard. On top of that, we've got over 1,000,000 hotel options globally to choose from. Talk about choice! No matter who you are, Expedia can show you the world.
Where should I stay in Sant Ambrogio?
A trip to Sant Ambrogio isn't complete until you've seen Cathedral of Santa Maria del Fiore and Ponte Vecchio. Book somewhere nearby for easy access to these popular attractions.
What are the top hotels in Sant Ambrogio?
Reserve a room at New Alfani. It's one of the area's most popular hotels. Another reputable option in Sant Ambrogio is Wine Apartments Florence Sangiovese.
How far in advance should I book my Sant Ambrogio holiday?
Travellers are generally able to compare international airfares on Expedia within 12 months of departure. Booking at the last minute? With a bit of luck, it's still possible to purchase an affordable ticket only weeks before your flight.
What does an Expedia Sant Ambrogio travel package include?
Expedia has everything you need to organise your Sant Ambrogio trip, but what your package looks like is your call. Choose from any combination of flights, hotels and rental cars. Searching for some activities to keep you on the move? Once you've made your booking, you can add them too. No matter your budget or style, there's a package deal to match your needs.
What should I know before booking a Sant Ambrogio travel package?
A travel package can be more affordable than individually booking everything you need for your escape. For example, combine your flights, hotels and rental cars and save a pretty penny. Whatever kind of holiday you're planning, you'll find a package that fits your budget.
Can I choose my airline with a Sant Ambrogio Expedia holiday package?
Yes, the choice is yours. We have access to over 550 airlines throughout the world, so you can tailor your Sant Ambrogio holiday according to your budget and needs.
If I'm not able to travel, can I cancel my Sant Ambrogio holiday package?
Don't worry if you're rethinking your Sant Ambrogio holiday package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your airline, hotel or car rental company. We realise life can sometimes throw you a curveball, so look up our Customer Service Portal if that happens. When you're ready to make changes, we're ready to help.

Things to do

Florence: San Gimignano, Siena, Monteriggioni, Chianti & Lunch with Wine

Florence: San Gimignano, Siena, Monteriggioni, Chianti & Lunch with Wine

€79
per adult
88% of travellers recommend
Florence: San Gimignano, Siena, Monteriggioni, Chianti & Lunch with Wine
The Best of Tuscany in One Day Sightseeing Tour

The Best of Tuscany in One Day Sightseeing Tour

€105
per adult
98% of travellers recommend
The Best of Tuscany in One Day Sightseeing Tour
City Sightseeing Florence Hop-on Hop-off

City Sightseeing Florence Hop-on Hop-off Bus Tour

€29
per adult
76% of travellers recommend
City Sightseeing Florence Hop-on Hop-off Bus Tour
See all activities in Florence
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.