Santa Clara Hotels

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31 Dec - 1 Jan
Tomorrow
1 Jan - 2 Jan
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

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Our top choices for Santa Clara hotels

Outdoor pool, open 7:00 AM to 10:30 PM, free pool cabanas
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.6 out of 10, Excellent, (1842)
"Better than expected: Location, transportation to and from airport, pool area tropical and comfortable. "
United States
Marty
The price is €117
includes taxes & fees
11 Jan - 12 Jan 2026
Riande Aeropuerto Hotel & Casino
Outdoor pool, pool loungers
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (4746)
"The rooms were nice and the food was great..great staff!!"
United States
Tffany
The price is €114
includes taxes & fees
12 Jan - 13 Jan 2026
Hotel Riu Plaza Panama
Suite, 1 Bedroom, Golf View (Terrace)
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (644)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is €203
includes taxes & fees
4 Jan - 5 Jan 2026
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Breakfast, lunch, dinner served; international cuisine
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
Cerro Viento
8.8 out of 10, Excellent, (1008)
"Location Location Location! Clean, safe, beautiful. Loved it!"
United States
Sharon Gobern Dorray and Jason
The price is €103
includes taxes & fees
29 Jan - 30 Jan 2026
Courtyard by Marriott Panama Metromall
2 outdoor pools, pool umbrellas, pool loungers
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador
8.4 out of 10, Very good, (1002)
"Unbeatable location if your visit is all about the Panama Canal. "
United States
Vitaliy
The price is €73
includes taxes & fees
18 Jan - 19 Jan 2026
Radisson Hotel Panama Canal
View from property
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2150)
"Great location of the hotel with a lovely breakfast and friendly staff"
United States
fouad
The price is €148
includes taxes & fees
4 Jan - 5 Jan 2026
Plaza Paitilla Inn Hotel
50-inch LED TV with satellite channels
Arcadia Condo Suites

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (177)
"Was a great buy. Beautiful views and spacious rooms. Great amenities. "
United States
Lesley
The price is €117
includes taxes & fees
19 Jan - 20 Jan 2026
Arcadia Condo Suites
Lobby
The Executive Hotel

The Executive Hotel

The Executive Hotel
3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (1014)
"A nice hotel to stay great location"
United States
angela
The price is €94
includes taxes & fees
2 Jan - 3 Jan 2026
The Executive Hotel
Terrace/patio
Sheraton Grand Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1002)
"Was amazing food was delicious and stay was great "
United States
Amanda
The price is €125
includes taxes & fees
11 Jan - 12 Jan 2026
Sheraton Grand Panama
4 outdoor pools, free pool cabanas, pool umbrellas
JW Marriott Panama

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1005)
"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
United States
Sarran
The price is €252
includes taxes & fees
30 Jan - 31 Jan 2026
JW Marriott Panama
Outdoor pool, pool umbrellas, pool loungers
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1131)
"The room was clean and the location was great."
United States
Wendy
The price is €103
includes taxes & fees
8 Jan - 9 Jan 2026
Ramada Plaza by Wyndham Panama Punta Pacifica
View from room
The Beach House

The Beach House

The Beach House
3.0 star property
Amador
8.4 out of 10, Very good, (411)
"Fantastic location on Amador Causeway and access to paddleboarding, restaurants, nightlife and family friendly events. One cool sloth in the tree overhanging the walkway at the Culebra nature area right by the prroperty."
United States
Cynthia
The Beach House
Restaurant
Hyatt Regency Panama City

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
Bella Vista
10.0 out of 10, Exceptional, (146)
"Breakfast was so good , hotel was clean "
United States
ankit
The price is €146
includes taxes & fees
4 Jan - 5 Jan 2026
Hyatt Regency Panama City
40-inch Smart TV with cable channels, TV
Renaissance Panama City Hotel

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (102)
"I stayed for nine nights and I enjoyed my time at this hotel I recommend this hotel for several days staff is nice and the hotel is worth it. "
United States
Sharon Isoken
The price is €103
includes taxes & fees
6 Jan - 7 Jan 2026
Renaissance Panama City Hotel
3 outdoor pools, pool umbrellas, pool loungers
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very good, (1004)
"Beautiful property and amazing staff"
United States
CARMEN
The price is €222
includes taxes & fees
30 Jan - 31 Jan 2026
The Westin Playa Bonita Panama
Outdoor pool
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
Bella Vista
9.0 out of 10, Wonderful, (630)
"Location is just ok as well as the breakfast."
Canada
john
The price is €93
includes taxes & fees
9 Jan - 10 Jan 2026
Waymore Hotel Spa & Casino
Terrace/patio
Marriott Panama Hotel

Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
Panama City
9.0 out of 10, Wonderful, (1005)
"Great hotel and staff!"
United States
Catherine
The price is €142
includes taxes & fees
31 Jan - 1 Feb 2026
Marriott Panama Hotel
Exterior
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (568)
"Amazing hotel , location , staff and amenities . Clean, elegant , great service. "
United States
Nicole
The price is €334
includes taxes & fees
13 Jan - 14 Jan 2026
Sofitel Legend Casco Viejo, Panama City
Exterior
Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
3.0 star property
San Francisco
The price is €181
includes taxes & fees
2 Jan - 3 Jan 2026
Dovle Residences by HMS-Preferred Member
Exterior
Hotel Milan

Hotel Milan

Hotel Milan
3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (434)
"It was a very pleasant experience the hotel is located in a great neighborhood, staff were friendly and competent, secure property and parking, clean and decent accommodations, especially at the room price point. "
Canada
Roger
The price is €37
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel Milan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santa Clara attractions

Culebra Cut

You can learn about the history of Santa Clara when you stop by Culebra Cut. Visit the casinos and top-notch restaurants in this walkable area.
See properties

Learn more about Santa Clara

Santa Clara awaits: its natural setting, monuments, history and more!

See all hotels in Santa Clara
Adobe

Top Santa Clara Hotel Reviews

Hyatt Regency Panama City

Hyatt Regency Panama City

10/10 Excellent
"The hotel was beautifully decorated for the holiday, the staff was very friendly and the rooms were clean. "
einat 1-night trip
Posted 1 day ago
Hyatt Regency Panama City

More cheap stays in Santa Clara

Panama House Bed & Breakfast

Panama House Bed & Breakfast

Calle 1era El Carmen- Casa # 32 Panama City
The price is €39 per night from 5 Jan to 6 Jan
€39
5 Jan - 6 Jan 2026
includes taxes & fees
8.8/10 Excellent! (185 reviews)

Frequently asked questions

What's the best place to stay in Santa Clara?
Located 15.8 mi (25.5 km) from the heart of Santa Clara, Hotel Riu Plaza Panama is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Megapolis Hotel Panamá and Las Americas Golden Tower Panama. See all available top hotels, or vacation rentals in Santa Clara.
What are some of the best holiday rentals that Santa Clara has to offer?
Oasis with pool near panama canal: This holiday home rental outside of Santa Clara offers an outdoor pool, a patio and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of garden in this rental home to help you unwind. See all vacation rentals in Santa Clara.
If I need to cancel my hotel reservation in Santa Clara, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Clara.
What is staying in Santa Clara like?
Visitors can enjoy all that Santa Clara has to offer, including its monuments. A top sight in the area is Albrook Shopping Mall. There are 1681 hotels and other accommodation options in the surrounding area. Find out more about Santa Clara.
What should I do while I'm visiting Santa Clara?
A favourite place to visit is Culebra Cut. Additionally, you'll find Albrook Shopping Mall in the area. Take a look at what more there is to see and do in Expedia's Santa Clara guide.
What's the weather like in Santa Clara?
The hottest months are usually April and March, with an average temperature of 26°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Santa Clara are July, August, November and October, with each month seeing an average of 283 mm of rainfall.