San Diego Hotel Guide. Hotels in Serra Mesa, San Diego, United States of America

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Our top choices for Serra Mesa hotels

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
28.1 km from Serra Mesa
9.0 out of 10, Wonderful, (1,256 reviews)
"Clean room, helpful and courteous staff, and fitness room was better than expected."
United States
Leyla
The price is €119
includes taxes & fees
21 Apr - 22 Apr
Best Western Americana Inn

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.8 km from Serra Mesa
9.4 out of 10, Exceptional, (1,849 reviews)
"The staff was extremely helpful, nice, clean, welcoming and respectful."
United States
Marcella
The price is €95
includes taxes & fees
14 Apr - 15 Apr
Sycuan Casino Resort

Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
18.5 km from Serra Mesa
9.4 out of 10, Exceptional, (1,095 reviews)
"Room was clean, amenities were stocked, breakfast was yummy. I would definitely stay there again."
United States
Fabiola
The price is €143
includes taxes & fees
26 Apr - 27 Apr
Holiday Inn Express San Diego South - Chula Vista by IHG

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
10.1 km from Serra Mesa
8.4 out of 10, Very good, (3,469 reviews)
"Nice hotel with great location "
United States
DIANA
The price is €195
includes taxes & fees
13 May - 14 May
Sheraton San Diego Resort

Hampton Inn & Suites San Diego Airport Liberty Station

Hampton Inn & Suites San Diego Airport Liberty Station
2.5 star property
10.6 km from Serra Mesa
9.2 out of 10, Wonderful, (1,715 reviews)
"Great location for the airport stay"
United States
Christopher
The price is €167
includes taxes & fees
26 Apr - 27 Apr
Hampton Inn & Suites San Diego Airport Liberty Station

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
9 km from Serra Mesa
7.4 out of 10, Good, (4,243 reviews)
"Front desk nice rooms clean "
United States
Alexis
The price is €96
includes taxes & fees
14 Apr - 15 Apr
Wyndham Garden San Diego Near SeaWorld

Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
4.0 star property
University City, 10.3 km from Serra Mesa
8.8 out of 10, Excellent, (1,916 reviews)
"Very clean property, nice location. Breakfast was great. "
United States
Vicki
The price is €226
includes taxes & fees
3 May - 4 May
Embassy Suites by Hilton San Diego La Jolla

GreenTree Inn San Diego Mission Bay

GreenTree Inn San Diego Mission Bay
2.5 star property
Pacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (2,028 reviews)
"Staff that works there were kind and very friendly."
United States
Jhonkeiver
The price is €102
includes taxes & fees
16 Apr - 17 Apr
GreenTree Inn San Diego Mission Bay

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
10.8 km from Serra Mesa
9.2 out of 10, Wonderful, (2,095 reviews)
"good atmosphere, good staff, friendly staff, good food, pool is amazing, restaurants are affordable and excellent."
United States
Artsrun
The price is €277
includes taxes & fees
1 May - 2 May
Marriott Marquis San Diego Marina

HYATT house San Diego/Sorrento Mesa

HYATT house San Diego/Sorrento Mesa
3.0 star property
11.8 km from Serra Mesa
9.0 out of 10, Wonderful, (1,005 reviews)
"Great staff, rooms are very clean and comfortable. "
United States
Chris
The price is €149
includes taxes & fees
3 May - 4 May
HYATT house San Diego/Sorrento Mesa

Best Western San Diego/Miramar Hotel

Best Western San Diego/Miramar Hotel
2.5 star property
10.1 km from Serra Mesa
7.8 out of 10, Good, (1,278 reviews)
"Parking was great no problems staff wonderful help with everything great breakfast great location will be back"
United States
David
The price is €117
includes taxes & fees
20 Apr - 21 Apr
Best Western San Diego/Miramar Hotel

Hampton Inn San Diego-Kearny Mesa

Hampton Inn San Diego-Kearny Mesa
2.5 star property
3.5 km from Serra Mesa
9.2 out of 10, Wonderful, (1,011 reviews)
"The rooms was a nice size and clean. The staff was nice and their breakfast was better than expected. "
United States
elisa
The price is €164
includes taxes & fees
24 Apr - 25 Apr
Hampton Inn San Diego-Kearny Mesa

Holiday Inn Express San Diego Airport - Old Town by IHG

Holiday Inn Express San Diego Airport - Old Town by IHG
2.5 star property
7.9 km from Serra Mesa
9.2 out of 10, Wonderful, (1,069 reviews)
"Clean room, friendly staff, and only a 15 minute walk to Old Town. Also conveniently located close to the airport just a short shuttle drive away. "
United States
Olivia
The price is €138
includes taxes & fees
26 Apr - 27 Apr
Holiday Inn Express San Diego Airport - Old Town by IHG

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
16.1 km from Serra Mesa
9.2 out of 10, Wonderful, (3,779 reviews)
"Clean room, comfy bed, and the staff were awesome. Pool and hot tub were the perfect temp."
United States
Danielle
The price is €143
includes taxes & fees
10 May - 11 May
Best Western Plus Marina Gateway Hotel

SpringHill Suites by Marriott Chula Vista Eastlake

SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
23.9 km from Serra Mesa
9.6 out of 10, Exceptional, (624 reviews)
"By far, one of the best hotels we have stayed at! Very clean, friendly and knowledgeable front desk staff, amenities galore and right across the street from family friendly entertainment venues like play city and ninja factory. The pool was amazing - we had all a great time! "
United States
Daniel
The price is €177
includes taxes & fees
3 May - 4 May
SpringHill Suites by Marriott Chula Vista Eastlake

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
9.9 km from Serra Mesa
8.4 out of 10, Very good, (6,153 reviews)
"Clean room and great location "
United States
Evanthia
The price is €189
includes taxes & fees
3 May - 4 May
Wyndham San Diego Bayside

Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown
4.0 star property
10.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1,725 reviews)
"Wonderful hotel and great location!! "
United States
Jan
The price is €231
includes taxes & fees
10 May - 11 May
Embassy Suites by Hilton San Diego Bay Downtown

The Encinitan Hotel & Suites

The Encinitan Hotel & Suites
3.0 star property
30.8 km from Serra Mesa
8.2 out of 10, Very good, (1,476 reviews)
"Great value being so close to all the attractions "
United States
Charlton
The price is €134
includes taxes & fees
14 Apr - 15 Apr
The Encinitan Hotel & Suites

Old Town Inn

Old Town Inn
2.5 star property
8.1 km from Serra Mesa
9.2 out of 10, Wonderful, (1,855 reviews)
"Clean room, friendly staff. Very nice Boutique Motel"
United States
Scott
The price is €163
includes taxes & fees
14 Apr - 15 Apr
Old Town Inn

Bahia Resort Hotel

Bahia Resort Hotel
3.5 star property
Central Mission Beach, 10.7 km from Serra Mesa
8.6 out of 10, Excellent, (1,979 reviews)
"Everything is perfect..location, staff, rooms, amenities, cleanliness."
United States
Ryan
The price is €223
includes taxes & fees
16 Apr - 17 Apr
Bahia Resort Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Pacific Beach

Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Gaslamp Quarter

San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Sunset Cliffs Natural Park.

Top Serra Mesa Hotel Reviews

Frequently asked questions

What's it like in Serra Mesa?
Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.
How many hotels can I expect to find in the Serra Mesa area?
Expedia has 38 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?
Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.
What can I see and do in this San Diego neighbourhood?
Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.

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