San Diego Hotel Guide. Hotels in Serra Mesa, San Diego, United States of America

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
21 Aug - 22 Aug
Tomorrow
22 Aug - 23 Aug
This weekend
22 Aug - 24 Aug
Next weekend
29 Aug - 31 Aug

Filter by

Guest rating
Guest rating
Property class

Top Trending Hotels Near Serra Mesa, San Diego

Balboa Park Hotel
Executive Studio Suite

Balboa Park Hotel

2.0 star property
7.8 out of 10, Good, (450)
"Everything about the property is fantastic. Hoping to stay here again soon."
The price is €82
includes taxes & fees
24 Aug - 25 Aug
Balboa Park Hotel
The Beau Downtown San Diego Gaslamp Quar
Front of property

The Beau Downtown San Diego Gaslamp Quar

3.0 star property
8.8 out of 10, Excellent, (394)
"The hotel was amazing I really liked the little coffee bar. "
The price is €149
includes taxes & fees
1 Sept - 2 Sept
The Beau Downtown San Diego Gaslamp Quar
Heritage Inn San Diego
Front of property

Heritage Inn San Diego

2.0 star property
7.0 out of 10, Good, (1005)
"Easy parking, safe , quiet..."
The price is €65
includes taxes & fees
24 Aug - 25 Aug
Heritage Inn San Diego
Coronado Beach Resort
Beach nearby

Coronado Beach Resort

3.0 star property
9.0 out of 10, Wonderful, (721)
"Great spot by the beach"
The price is €195
includes taxes & fees
2 Sept - 3 Sept
Coronado Beach Resort
Sun Outdoors San Diego Bay
Outdoor pool, pool cabanas (surcharge), pool umbrellas

Sun Outdoors San Diego Bay

2.0 star property
10.0 out of 10, Exceptional, (73)
"A good place to stay with the whole family"
The price is €220
includes taxes & fees
2 Sept - 3 Sept
Sun Outdoors San Diego Bay
Heritage Inn La Mesa
Outdoor pool, pool umbrellas, pool loungers

Heritage Inn La Mesa

2.0 star property
6.6 out of 10, (1057)
"Nice place and close to dining "
The price is €66
includes taxes & fees
24 Aug - 25 Aug
Heritage Inn La Mesa
The Horton Grand, Downtown/Gaslamp Quarter
Serves dinner and happy hour

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
9.0 out of 10, Wonderful, (2461)
"We enjoyed our stay."
The Horton Grand, Downtown/Gaslamp Quarter
Catamaran Resort and Spa
View from room

Catamaran Resort and Spa

4.0 star property
8.4 out of 10, Very good, (1021)
"Great view, great food, comfortable room!"
The price is €248
includes taxes & fees
24 Aug - 25 Aug
Catamaran Resort and Spa
Crowne Plaza San Diego - Mission Valley by IHG
Outdoor pool

Crowne Plaza San Diego - Mission Valley by IHG

3.5 star property
7.6 out of 10, Good, (1004)
"Great place to stay"
The price is €109
includes taxes & fees
26 Aug - 27 Aug
Crowne Plaza San Diego - Mission Valley by IHG
El Cordova Hotel on Coronado Island
Lobby

El Cordova Hotel on Coronado Island

3.5 star property
8.8 out of 10, Excellent, (1003)
"Loved our stay at El Cordova Hotel! The on-site restaurant was super convenient, the whole place had a cozy, homey vibe, and we were just minutes from Coronado Beach. Excellent experience all around!"
The price is €239
includes taxes & fees
4 Sept - 5 Sept
El Cordova Hotel on Coronado Island
The Atwood Hotel San Diego - SeaWorld/Zoo
Hot springs

The Atwood Hotel San Diego - SeaWorld/Zoo

3.0 star property
7.8 out of 10, Good, (1825)
"Good location. Close to attractions. "
The Atwood Hotel San Diego - SeaWorld/Zoo
The Inn at Sunset Cliffs
Property grounds

The Inn at Sunset Cliffs

2.5 star property
9.2 out of 10, Wonderful, (1003)
"Great quiet peaceful place to stay"
The price is €194
includes taxes & fees
24 Aug - 25 Aug
The Inn at Sunset Cliffs
E-Z 8 Motel Old Town
Exterior

E-Z 8 Motel Old Town

2.5 star property
6.4 out of 10, (2128)
"It was a nice place to stay the staff was very helpful "
The price is €61
includes taxes & fees
24 Aug - 25 Aug
E-Z 8 Motel Old Town
Gaslamp Plaza Suites
Lobby

Gaslamp Plaza Suites

3.5 star property
8.8 out of 10, Excellent, (1002)
"Great place and location. Nice rooftop"
The price is €102
includes taxes & fees
27 Aug - 28 Aug
Gaslamp Plaza Suites
Glorietta Bay Inn Coronado Island
Front of property – evening/night

Glorietta Bay Inn Coronado Island

3.5 star property
8.6 out of 10, Excellent, (1000)
"Excellent staff and location."
The price is €240
includes taxes & fees
25 Aug - 26 Aug
Glorietta Bay Inn Coronado Island
SpringHill Suites by Marriott Chula Vista Eastlake
Outdoor pool

SpringHill Suites by Marriott Chula Vista Eastlake

3.5 star property
9.6 out of 10, Exceptional, (414)
"Nice pool and decent breakfast"
The price is €130
includes taxes & fees
7 Sept - 8 Sept
SpringHill Suites by Marriott Chula Vista Eastlake
Lamplighter Inn & Suites at SDSU
Outdoor pool, pool umbrellas, pool loungers

Lamplighter Inn & Suites at SDSU

2.5 star property
9.0 out of 10, Wonderful, (1237)
"We will definitely be staying there again"
The price is €139
includes taxes & fees
1 Sept - 2 Sept
Lamplighter Inn & Suites at SDSU
Sycuan Casino Resort
3 outdoor pools, pool cabanas (surcharge), pool umbrellas

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1502)
"The rooms are very clean and the restaurant options are good too."
Sycuan Casino Resort
Pleasant Inn
1 bedroom, desk, laptop workspace, blackout curtains

Pleasant Inn

2.5 star property
8.4 out of 10, Very good, (1117)
"Friendly staff and excellent place"
The price is €92
includes taxes & fees
28 Aug - 29 Aug
Pleasant Inn
Surfer Beach Hotel
On the beach, surfing

Surfer Beach Hotel

3.0 star property
8.0 out of 10, Very good, (1072)
"Great location, awesome staff, and super comfortable beds. "
The price is €173
includes taxes & fees
2 Sept - 3 Sept
Surfer Beach Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.

Downtown San Diego

2 out of top 10 points of interest in this area

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Belmont Park which includes rides and a garden

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.

Pacific Beach featuring a beach

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Crystal Pier while you're exploring the area.

Gaslamp Quarter featuring a city, signage and a bar

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Ocean Beach Pier and Dog Beach.

Top Serra Mesa Hotel Reviews

Bay Club Hotel & Marina

Bay Club Hotel & Marina

10/10 Excellent
"Good location, friendly staff, spacious rooms "
Edgard 2-night trip
Posted 17 hours ago
Bay Club Hotel & Marina

Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighbourhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

How many hotels can I expect to find in the Serra Mesa area?

Expedia has 37 hotels and other accommodation options in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review top deals in Serra Mesa.

What can I see and do in this San Diego neighbourhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.