San Diego Hotel Guide. Hotels in Serra Mesa, San Diego, United States of America
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Serra Mesa hotels
Best Western Americana Inn
Best Western Americana Inn28.1 km from Serra Mesa
9.0 out of 10, Wonderful, (1,256 reviews)
"Clean room, helpful and courteous staff, and fitness room was better than expected."
Leyla
The price is €119
includes taxes & fees
21 Apr - 22 Apr
Sycuan Casino Resort
Sycuan Casino Resort28.8 km from Serra Mesa
9.4 out of 10, Exceptional, (1,849 reviews)
"The staff was extremely helpful, nice, clean, welcoming and respectful."
Marcella
The price is €95
includes taxes & fees
14 Apr - 15 Apr
Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHG18.5 km from Serra Mesa
9.4 out of 10, Exceptional, (1,095 reviews)
"Room was clean, amenities were stocked, breakfast was yummy. I would definitely stay there again."
Fabiola
The price is €143
includes taxes & fees
26 Apr - 27 Apr
Sheraton San Diego Resort
Sheraton San Diego Resort10.1 km from Serra Mesa
8.4 out of 10, Very good, (3,469 reviews)
"Nice hotel with great location "
DIANA
The price is €195
includes taxes & fees
13 May - 14 May
Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty Station10.6 km from Serra Mesa
9.2 out of 10, Wonderful, (1,715 reviews)
"Great location for the airport stay"
Christopher
The price is €167
includes taxes & fees
26 Apr - 27 Apr
Wyndham Garden San Diego Near SeaWorld
Wyndham Garden San Diego Near SeaWorld9 km from Serra Mesa
7.4 out of 10, Good, (4,243 reviews)
"Front desk nice rooms clean "
Alexis
The price is €96
includes taxes & fees
14 Apr - 15 Apr
Embassy Suites by Hilton San Diego La Jolla
Embassy Suites by Hilton San Diego La JollaUniversity City, 10.3 km from Serra Mesa
8.8 out of 10, Excellent, (1,916 reviews)
"Very clean property, nice location.
Breakfast was great.
"
Vicki
The price is €226
includes taxes & fees
3 May - 4 May
GreenTree Inn San Diego Mission Bay
GreenTree Inn San Diego Mission BayPacific Beach, 7.3 km from Serra Mesa
8.0 out of 10, Very good, (2,028 reviews)
"Staff that works there were kind and very friendly."
Jhonkeiver
The price is €102
includes taxes & fees
16 Apr - 17 Apr
Marriott Marquis San Diego Marina
Marriott Marquis San Diego Marina10.8 km from Serra Mesa
9.2 out of 10, Wonderful, (2,095 reviews)
"good atmosphere, good staff, friendly staff, good food, pool is amazing, restaurants are affordable and excellent."
Artsrun
The price is €277
includes taxes & fees
1 May - 2 May
HYATT house San Diego/Sorrento Mesa
HYATT house San Diego/Sorrento Mesa11.8 km from Serra Mesa
9.0 out of 10, Wonderful, (1,005 reviews)
"Great staff, rooms are very clean and comfortable. "
Chris
The price is €149
includes taxes & fees
3 May - 4 May
Best Western San Diego/Miramar Hotel
Best Western San Diego/Miramar Hotel10.1 km from Serra Mesa
7.8 out of 10, Good, (1,278 reviews)
"Parking was great no problems staff wonderful help with everything great breakfast great location will be back"
David
The price is €117
includes taxes & fees
20 Apr - 21 Apr
Hampton Inn San Diego-Kearny Mesa
Hampton Inn San Diego-Kearny Mesa3.5 km from Serra Mesa
9.2 out of 10, Wonderful, (1,011 reviews)
"The rooms was a nice size and clean. The staff was nice and their breakfast was better than expected. "
elisa
The price is €164
includes taxes & fees
24 Apr - 25 Apr
Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHG7.9 km from Serra Mesa
9.2 out of 10, Wonderful, (1,069 reviews)
"Clean room, friendly staff, and only a 15 minute walk to Old Town. Also conveniently located close to the airport just a short shuttle drive away. "
Olivia
The price is €138
includes taxes & fees
26 Apr - 27 Apr
Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.1 km from Serra Mesa
9.2 out of 10, Wonderful, (3,779 reviews)
"Clean room, comfy bed, and the staff were awesome. Pool and hot tub were the perfect temp."
Danielle
The price is €143
includes taxes & fees
10 May - 11 May
SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake23.9 km from Serra Mesa
9.6 out of 10, Exceptional, (624 reviews)
"By far, one of the best hotels we have stayed at! Very clean, friendly and knowledgeable front desk staff, amenities galore and right across the street from family friendly entertainment venues like play city and ninja factory. The pool was amazing - we had all a great time! "
Daniel
The price is €177
includes taxes & fees
3 May - 4 May
Wyndham San Diego Bayside
Wyndham San Diego Bayside9.9 km from Serra Mesa
8.4 out of 10, Very good, (6,153 reviews)
"Clean room and great location "
Evanthia
The price is €189
includes taxes & fees
3 May - 4 May
Embassy Suites by Hilton San Diego Bay Downtown
Embassy Suites by Hilton San Diego Bay Downtown10.6 km from Serra Mesa
9.0 out of 10, Wonderful, (1,725 reviews)
"Wonderful hotel and great location!! "
Jan
The price is €231
includes taxes & fees
10 May - 11 May
The Encinitan Hotel & Suites
The Encinitan Hotel & Suites30.8 km from Serra Mesa
8.2 out of 10, Very good, (1,476 reviews)
"Great value being so close to all the attractions "
Charlton
The price is €134
includes taxes & fees
14 Apr - 15 Apr
Old Town Inn
Old Town Inn8.1 km from Serra Mesa
9.2 out of 10, Wonderful, (1,855 reviews)
"Clean room, friendly staff. Very nice Boutique Motel"
Scott
The price is €163
includes taxes & fees
14 Apr - 15 Apr
Bahia Resort Hotel
Bahia Resort HotelCentral Mission Beach, 10.7 km from Serra Mesa
8.6 out of 10, Excellent, (1,979 reviews)
"Everything is perfect..location, staff, rooms, amenities, cleanliness."
Ryan
The price is €223
includes taxes & fees
16 Apr - 17 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Serra Mesa
Find the best Serra Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Mission Beach
If you're spending some time in Mission Beach, Mission Bay and Mission Beach are top sights worth seeing.
Gaslamp Quarter
San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.
Ocean Beach
Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Sunset Cliffs Natural Park.
Frequently asked questions
Explore a world of travel with Expedia
- Allied Gardens Hotels
- Hotels near Balboa Park
- Bankers Hill Hotels
- Bay Park Hotels
- Civic Core Hotels
- Clairemont Hotels
- East Village Hotels
- Fairmount Park Hotels
- Resorts in Fiesta Island
- Hillcrest Hotels
- Hotels near Hotel Circle
- Kearny Mesa Hotels
- Liberty Station Hotels
- Linda Vista Hotels
- Little Italy Hotels
- Hotels near Marine Corps Recruit Depot
- Hotels near Mission Bay
- Hotels near Mission Valley Mall
- Casino Hotels in Mission Valley
- Cheap Hotels in Mission Valley
- Mission Valley Hotels
- Beach Hotels in North Park
- North Park Hotels
- Old Town San Diego Hotels
- Hotels near Our Lady of the Rosary Catholic Church
- Rolando Village Hotels
- San Diego Hotels
- Hotels near San Diego Intl.
- Hotels near San Diego State University
- Hotels near San Diego Zoo
- Hotels near Seaport Village
- South Park Hotels
- Hotels near Stadium Golf Center & Batting Cages
- Hotels near USS Midway Museum
- Flights from Montgomery Field
- Flights from San Diego Intl.
- Air France London (LHR) to San Diego (SAN) flights
- Iberia London (LHR) to San Diego (SAN) flights
- Jetblue Airways Raleigh (RDU) to San Diego (SAN) flights
- Flights from Eureka (ACV) to San Diego (SAN)
- Flights from Alesund (AES) to San Diego (SAN)
- Flights from Auckland (AKL) to San Diego (MYF)
- Flights from Amman (AMM) to San Diego (MYF)
- Flights from Atlanta (ATL) to San Diego (MYF)
- Flights from Barranquilla (BAQ) to San Diego (SAN)
- Flights from Bangkok (BKK) to San Diego (SAN)
- Flights from Boston (BOS) to San Diego (SAN)
- Flights from Bristol (BRS) to San Diego (SAN)
- Flights from Baltimore (BWI) to San Diego (SAN)
- Flights from Paris (CDG) to San Diego (SAN)
- Flights from Crescent City (CEC) to San Diego (SAN)
- Flights from Charleston (CHS) to San Diego (SAN)
- Flights from Chico (CIC) to San Diego (MYF)
- Flights from Chico (CIC) to San Diego (SAN)
- Flights from Chi Mei (CMJ) to San Diego (SAN)
- Flights from Concord (CON) to San Diego (MYF)
- Flights from Denver (DEN) to San Diego (SAN)
- Flights from Newark Liberty Intl. Airport (EWR) to San Diego (SAN)
- Flights from Fort Lauderdale (FLL) to San Diego (MYF)
- Flights from Gabala (GBB) to San Diego (SAN)
- Flights from Washington (IAD) to San Diego (SAN)
- Flights from Indianapolis (IND) to San Diego (SAN)
- Flights from New York (JFK) to San Diego (MYF)
- Flights from Ganzhou (KOW) to San Diego (SAN)
- Flights from Lake Charles (LCH) to San Diego (MYF)
- Flights from Orlando (MCO) to San Diego (SAN)
- Flights from Manta (MEC) to San Diego (MYF)
- Flights from Medford (MFR) to San Diego (SAN)
- Flights from Modesto (MOD) to San Diego (MYF)
- Flights from Mesa (MSC) to San Diego (MYF)
- Flights from Missoula (MSO) to San Diego (SAN)
- Flights from Oceanside (OCN) to San Diego (MYF)
- Flights from Pago Pago (PPG) to San Diego (MYF)
- Flights from Busan (PUS) to San Diego (SAN)
- Flights from Richmond (RIC) to San Diego (SAN)
- Flights from Richland (RLD) to San Diego (MYF)
- Flights from San Antonio (SAT) to San Diego (SAN)
- Flights from San Francisco (SFO) to San Diego (MYF)
- Flights from San Juan (SJU) to San Diego (SAN)
- Flights from Santa Monica (SMO) to San Diego (MYF)
- Flights from Orange County (SNA) to San Diego (MYF)
- Flights from Salinas (SNS) to San Diego (SAN)
- Flights from Santa Ynez (SQA) to San Diego (MYF)
- Flights from Sydney (SYD) to San Diego (SAN)
- Flights from Thermal (TRM) to San Diego (MYF)
- Flights from Wellington (WLG) to San Diego (SAN)