South San Diego La Quinta Inn & Suites Hotels: South San Diego Hotel Guide

A beach with a pier extending into the ocean, a person standing on the shore, and the sun setting over the water.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for South San Diego La Quinta Inn & Suites

1. La Quinta Inn by Wyndham San Diego Chula Vista

Chula Vista

Andrea

includes taxes & fees

16 Aug - 17 Aug

2. La Quinta Inn & Suites by Wyndham San Diego Mission Bay

Pacific Beach

Jose

includes taxes & fees

31 Aug - 1 Sept

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top South San Diego Hotel Reviews

Handlery Hotel

10/10 Excellent

"Super amazing staff, very friendly and attentive. Definitely cannot wait to stay again"

The Sofia Hotel

10/10 Excellent

"Staff was great, room was a bit smaller than expected but worked well for my family of 3. There was a hot water issue but fixed right away and one day we were left with no towels but again immediately corrected when we asked, brought up within 5 mins. I could see dust around the closet edges but the bed was always made and sheets clean. Also one of the elevators was broken which made a bit of longer wait at times. Great location to walk to seaport, midway little Italy or the convention center with a lot of restaurants. It was great to have parking available as well and not have to worry about that being downtown."