South San Diego Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for South San Diego hotels

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.2 out of 10, Very good, (1,750 reviews)
"Clean, friendly staff, great breakfast!!"
United States
Flor
The price is €137
includes taxes & fees
28 Jun - 29 Jun
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
San Ysidro
8.8 out of 10, Excellent, (1,316 reviews)
"The breakfast was great, the staff was helpful, and the room was clean and spacious!"
United States
Christopher
The price is €120
includes taxes & fees
28 Jun - 29 Jun
Best Western Americana Inn

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.2 out of 10, Good, (1,012 reviews)
"Very clean, bed was comfortable!"
United States
Michael A
The price is €111
includes taxes & fees
21 Jun - 22 Jun
Quality Suites San Diego Otay Mesa

Rodeway Inn San Diego South San Ysidro Border

Rodeway Inn San Diego South San Ysidro Border
2.0 star property
San Ysidro
7.8 out of 10, Good, (62 reviews)
"Had a pleasant stay , very clean"
United States
maddy
The price is €71
includes taxes & fees
28 Jun - 29 Jun
Rodeway Inn San Diego South San Ysidro Border

Ayres Hotel San Diego South - Chula Vista

Ayres Hotel San Diego South - Chula Vista
3.0 star property
Otay Ranch
9.8 out of 10, Exceptional, (1,107 reviews)
"Nice place good food for breakfast 👍"
United States
Paul
The price is €202
includes taxes & fees
12 Jul - 13 Jul
Ayres Hotel San Diego South - Chula Vista

Comfort Inn Chula Vista San Diego South

Comfort Inn Chula Vista San Diego South
2.5 star property
Chula Vista
8.2 out of 10, Very good, (1,552 reviews)
"The room was comfortable and conveniently located. Breakfast was great for the cost of our stay."
United States
Arsenia P
The price is €120
includes taxes & fees
8 Jul - 9 Jul
Comfort Inn Chula Vista San Diego South

Hampton Inn & Suites Imperial Beach San Diego

Hampton Inn & Suites Imperial Beach San Diego
2.5 star property
Imperial Beach
9.4 out of 10, Exceptional, (1,007 reviews)
"Good time and stay "
United States
Ana
The price is €167
includes taxes & fees
29 Jun - 30 Jun
Hampton Inn & Suites Imperial Beach San Diego

La Quinta Inn by Wyndham San Diego Chula Vista

La Quinta Inn by Wyndham San Diego Chula Vista
3.0 star property
Chula Vista
8.6 out of 10, Excellent, (1,627 reviews)
"Great place to stay at, would definitely stay there again."
United States
Jose
The price is €120
includes taxes & fees
5 Jul - 6 Jul
La Quinta Inn by Wyndham San Diego Chula Vista

Motel 6 San Ysidro, CA - San Diego - Border

Motel 6 San Ysidro, CA - San Diego - Border
2.0 star property
San Ysidro
7.2 out of 10, Good, (1,511 reviews)
"easy parking, close to border."
United States
Angel
The price is €73
includes taxes & fees
18 Jun - 19 Jun
Motel 6 San Ysidro, CA - San Diego - Border

Studio 6 Suites San Ysidro, CA -San Diego South Bay

Studio 6 Suites San Ysidro, CA -San Diego South Bay
2.5 star property
San Ysidro
8.0 out of 10, Very good, (1,682 reviews)
"It’s ok to stay one or two days"
United States
Valentina
The price is €78
includes taxes & fees
22 Jun - 23 Jun
Studio 6 Suites San Ysidro, CA -San Diego South Bay

Holiday Inn Express San Diego South - Chula Vista by IHG

Holiday Inn Express San Diego South - Chula Vista by IHG
2.5 star property
Chula Vista
9.4 out of 10, Exceptional, (1,242 reviews)
"We had a very wonderful time at our stay here"
United States
Liezl
The price is €155
includes taxes & fees
5 Jul - 6 Jul
Holiday Inn Express San Diego South - Chula Vista by IHG

Best Western Chula Vista/Otay Valley Hotel

Best Western Chula Vista/Otay Valley Hotel
2.5 star property
Otay
8.0 out of 10, Very good, (1,797 reviews)
"The stay was great, and breakfast was delicious"
United States
Katie
The price is €120
includes taxes & fees
28 Jun - 29 Jun
Best Western Chula Vista/Otay Valley Hotel

Residence Inn by Marriott San Diego Chula Vista

Residence Inn by Marriott San Diego Chula Vista
3.0 star property
Otay Ranch
9.4 out of 10, Exceptional, (587 reviews)
"Great staff easy to find rooms"
United States
John
The price is €241
includes taxes & fees
28 Jun - 29 Jun
Residence Inn by Marriott San Diego Chula Vista

Valli Hi Motel

Valli Hi Motel
2.5 star property
San Ysidro
8.4 out of 10, Very good, (1,027 reviews)
"Great place to stay."
United States
Allan
The price is €88
includes taxes & fees
18 Jun - 19 Jun
Valli Hi Motel

The Rambler Hotel

The Rambler Hotel
3.0 star property
Chula Vista
9.0 out of 10, Wonderful, (2,151 reviews)
"It was the best hotel I've stayed in traveling the lower 48 I've stayed in a long time"
United States
Joey
The price is €129
includes taxes & fees
22 Jun - 23 Jun
The Rambler Hotel

SureStay Hotel by Best Western Chula Vista San Diego Bay

SureStay Hotel by Best Western Chula Vista San Diego Bay
3.0 star property
Chula Vista
8.0 out of 10, Very good, (1,747 reviews)
"Very nice hotel and quiet"
United States
Jerome
The price is €102
includes taxes & fees
29 Jun - 30 Jun
SureStay Hotel by Best Western Chula Vista San Diego Bay

Hampton Inn Chula Vista Eastlake

Hampton Inn Chula Vista Eastlake
2.5 star property
Chula Vista
9.2 out of 10, Wonderful, (1,019 reviews)
"I have stayed several times Over the years the staff and property have always been excellent. Great breakfast. Rooms are always well maintained."
United States
Donald
The price is €217
includes taxes & fees
28 Jun - 29 Jun
Hampton Inn Chula Vista Eastlake

Gaylord Pacific Resort & Convention Center

Gaylord Pacific Resort & Convention Center
4.0 star property
Chula Vista
8.6 out of 10, Excellent, (380 reviews)
"Beautiful hotel great hotel for a staycation "
United States
Lupe
The price is €383
includes taxes & fees
6 Jul - 7 Jul
Gaylord Pacific Resort & Convention Center

Motel 6 San Diego, CA - Southbay

Motel 6 San Diego, CA - Southbay
2.0 star property
Nestor
7.4 out of 10, Good, (1,006 reviews)
"Clean and friendly staff"
United States
Monica
The price is €87
includes taxes & fees
18 Jun - 19 Jun
Motel 6 San Diego, CA - Southbay

ERTH INN by AGA- San Ysidro

ERTH INN by AGA- San Ysidro
2.5 star property
San Ysidro
7.2 out of 10, Good, (153 reviews)
"Loved my stay"
United States
yashkumar
The price is €86
includes taxes & fees
18 Jun - 19 Jun
ERTH INN by AGA- San Ysidro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular South San Diego attractions

Learn more about South San Diego

Explore the family-friendly area of South San Diego—live music, theatres and sights from Sesame Place San Diego to North Island Credit Union Amphitheatre.

Photo by Karen Leone
Open Photo by Karen Leone

Top South San Diego Hotel Reviews

More cheap stays in South San Diego

Explore a world of travel with Expedia