4 Star Hotels in South San Diego, California

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on South San Diego 4 Star Hotels

This weekend
Next weekend

Our top choices for South San Diego 4-star hotels

Hotel del Coronado, Curio Collection by Hilton

Hotel del Coronado, Curio Collection by Hilton
4.0 star property
Historic Downtown Coronado
8.4 out of 10, Very good, (1008)
"Beautiful resort in the heart l"
United States
Marc
The price is €367
includes taxes & fees
8 Jan - 9 Jan 2026
Hotel del Coronado, Curio Collection by Hilton

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (3173)
"Beautiful hotel"
United States
Jordan M.
The price is €207
includes taxes & fees
30 Dec - 31 Dec
Hard Rock Hotel San Diego

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
Mission Valley
8.4 out of 10, Very good, (1437)
"The room was super quiet and clean. The staff was kind at check in and check out. We would definitely stay here again. "
United States
Janelle
The price is €110
includes taxes & fees
3 Jan - 4 Jan 2026
DoubleTree by Hilton Hotel San Diego - Mission Valley

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (144)
"Great place to stay "
United States
Jacorey
The price is €120
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott San Diego Downtown Little Italy

Hilton San Diego Mission Valley

Hilton San Diego Mission Valley
4.0 star property
Mission Valley
8.0 out of 10, Very good, (2262)
"Loved the easy check in process via the app! "
United States
Larizza
The price is €120
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton San Diego Mission Valley

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2942)
"Great boutique hotel!!"
United States
Maksim
Legacy Resort Hotel & Spa

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
Downtown San Diego
8.4 out of 10, Very good, (6040)
"Always an amazing stay"
United States
Jana
The price is €158
includes taxes & fees
3 Jan - 4 Jan 2026
Wyndham San Diego Bayside

Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1558)
"Perfect location , friendly staff , good buffet"
United States
Patricio
The price is €200
includes taxes & fees
4 Jan - 5 Jan 2026
Embassy Suites by Hilton San Diego Bay Downtown

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
University Heights
9.4 out of 10, Exceptional, (1366)
"Amazing hotel, great staff and awesome food!"
United States
michael
The price is €223
includes taxes & fees
30 Dec - 31 Dec
Lafayette Hotel & Club

Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel
4.0 star property
Mission Valley
8.6 out of 10, Excellent, (1685)
"Great hotel, close to shops, freeway and restaurants. "
United States
Esteban
The price is €132
includes taxes & fees
4 Jan - 5 Jan 2026
Sheraton Mission Valley San Diego Hotel

Embassy Suites by Hilton San Diego La Jolla

Embassy Suites by Hilton San Diego La Jolla
4.0 star property
University City
8.8 out of 10, Excellent, (1799)
"Really enjoyed the included breakfast and complimentary happy hour. Rooms were clean. Staff was very nice. "
United States
Maureen
The price is €180
includes taxes & fees
4 Jan - 5 Jan 2026
Embassy Suites by Hilton San Diego La Jolla

The Westin San Diego Bayview

The Westin San Diego Bayview
4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1087)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
The price is €181
includes taxes & fees
30 Dec - 31 Dec
The Westin San Diego Bayview

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2885)
"Everything was great and so convenient to everywhere we wanted to go to"
United States
Julio J
The price is €220
includes taxes & fees
30 Dec - 31 Dec
Manchester Grand Hyatt San Diego

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (1962)
"Best place to stay with family in San diego"
United States
vishakha
The price is €217
includes taxes & fees
4 Jan - 5 Jan 2026
Marriott Marquis San Diego Marina

Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1176)
"Amenities and location were great. "
United States
Julie
The price is €211
includes taxes & fees
30 Dec - 31 Dec
Margaritaville Hotel San Diego Gaslamp Quarter

San Diego Marriott Mission Valley

San Diego Marriott Mission Valley
4.0 star property
Mission Valley
8.8 out of 10, Excellent, (1002)
"Staff was polite , room service amazing "
Canada
Francois
The price is €155
includes taxes & fees
11 Jan - 12 Jan 2026
San Diego Marriott Mission Valley

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2053)
"Very comfortable, nice location and good service "
United States
ALEXANDER
The price is €230
includes taxes & fees
3 Jan - 4 Jan 2026
Omni San Diego Hotel at the Ballpark

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
Harbor Island
8.4 out of 10, Very good, (3194)
"The stay and staff were wonderful and very helpful.."
United States
Elsie
The price is €153
includes taxes & fees
30 Dec - 31 Dec
Sheraton San Diego Resort

InterContinental San Diego by IHG

InterContinental San Diego by IHG
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1132)
"Room was great, the amenities great, overall very nice. "
United States
Crystal
The price is €258
includes taxes & fees
4 Jan - 5 Jan 2026
InterContinental San Diego by IHG

Catamaran Resort and Spa

Catamaran Resort and Spa
4.0 star property
Mission Beach
8.6 out of 10, Excellent, (1115)
"Great place to vacation. "
United States
Manuel
The price is €185
includes taxes & fees
29 Jan - 30 Jan 2026
Catamaran Resort and Spa
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in South San Diego.
Still don't see what you're looking for?
See all properties in South San Diego.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about South San Diego

Explore the family-friendly area of South San Diego—live music, theatres and sights from Sesame Place San Diego to North Island Credit Union Amphitheatre.

Captured this guy doing a wheelie during a beautiful sunset! #imperialbeach #EndlessSummer #autographhotels #Marriott #piersouthresort
Photo by Karen Leone
Open Photo by Karen Leone

Top South San Diego Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in South San Diego?
Based on reviews by Expedia customers, Pier South Resort, Autograph Collection by Marriott is one of the most popular in South San Diego. Featuring lots of handy amenities and an outstanding guest experience, this 4-star hotel in Imperial Beach promises an unforgettable holiday.
How much does it cost to stay in a 4-star hotel in South San Diego?
Expedia can help you easily track down the perfect 4-star hotel for your stay in South San Diego. Use our filter tool to tailor your search by things like budget, conveniences and property star rating and get access to unbeatable deals in a few clicks.

  • Search for the lowest price from €299

What's the difference between 5-star and 4-star hotels in South San Diego?
If you choose to book a stay at a 4-star hotel in South San Diego, you'll usually find lots of conveniences to make sure you're relaxed, such as a gym, restaurant and pool. You can look forward to high-quality service and upmarket accommodation. Pick a 5-star hotel and you'll have access to a few extra bells and whistles — think around-the-clock concierge, on-site spas and indulgent turndown services. You're likely to get extra amenities and first-class services at a 5-star retreat, though both are superb options for luxury travellers.

Explore a world of travel with Expedia