South San Diego Hotels with Spa, California: South San Diego Hotel Guide

A beach with a pier extending into the ocean, a person standing on the shore, and the sun setting over the water.

A beach with a pier extending into the ocean, a person standing on the shore, and the sun setting over the water.

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Check availability on South San Diego Hotels with Spa

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13 Nov - 15 Nov

Our top choices for South San Diego hotels with a spa

A modern kitchen area with a self-serve station, including a waffle maker, coffee machine, and various food items.

1. Best Western Chula Vista/Otay Valley Hotel

Otay

United States

Mario

includes taxes & fees

8 Nov - 9 Nov

A spacious lobby with a modern design, featuring a large seating area, a reception desk, and large windows offering views of the city.

2. Ayres Hotel San Diego South - Chula Vista

Otay Ranch

United States

Rosemary

includes taxes & fees

29 Nov - 30 Nov

A breakfast bar with La Quinta branding, a coffee machine, and a waffle display.

3. La Quinta Inn by Wyndham San Diego Chula Vista

Chula Vista

United States

Nuwan

includes taxes & fees

29 Nov - 30 Nov

A spacious lobby with a fireplace, wooden furniture, and a chandelier.

4. Best Western Americana Inn

San Ysidro

United States

Erika

includes taxes & fees

8 Nov - 9 Nov

An outdoor seating area with fire pit, lounge chairs, and tables, adjacent to a building with large windows and a brick facade.

5. Hampton Inn Chula Vista Eastlake

Chula Vista

United States

jose

includes taxes & fees

15 Nov - 16 Nov

A modern interior with a long table and blue chairs, large windows with a view of palm trees and parked vehicles outside.

6. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Otay Mesa

United States

Helen

includes taxes & fees

8 Nov - 9 Nov

A spacious lobby with a flat-screen TV, a fireplace, and comfortable seating areas.

7. Residence Inn by Marriott San Diego Chula Vista

Otay Ranch

United States

Leslie

includes taxes & fees

30 Nov - 1 Dec

A hotel lobby with a patterned carpet, a reception desk, a sofa with cushions, and potted plants.

8. Comfort Inn Chula Vista San Diego South

Chula Vista

United States

Xochitl

includes taxes & fees

29 Nov - 30 Nov

A room with two teal armchairs, a small round table with a lamp, and a large cityscape painting on the wall.

9. SureStay Hotel by Best Western Chula Vista San Diego Bay

Chula Vista

Brazil

Sergio

includes taxes & fees

8 Nov - 9 Nov

A hotel with a large pool area, multiple lounge chairs, and umbrellas.

10. Sun Outdoors San Diego Bay

Chula Vista

United States

Faebyan

includes taxes & fees

9 Nov - 10 Nov

A modern living room with a sofa, a coffee table, and a TV mounted on the wall.

11. Hercor Hotel - Urban Boutique

Chula Vista

United States

fannie

includes taxes & fees

29 Nov - 30 Nov

A living room with two sofas, a round coffee table, a TV mounted on the wall, and a large window with curtains.

12. El Primero Hotel

Downtown Chula Vista

United States

Richard

includes taxes & fees

2 Nov - 3 Nov

A spacious lobby with a large seating area, a reception desk, and a television screen.

13. Element by Marriott San Diego Chula Vista

Otay Ranch

United States

Maricela

includes taxes & fees

8 Nov - 9 Nov

A modern living room with a large window, a fireplace, and a kitchen area.

14. Rodeway Inn San Diego South San Ysidro Border

San Ysidro

United States

Guadalupe

includes taxes & fees

8 Nov - 9 Nov

An outdoor patio with a fire feature, seating, and large windows.

15. Hampton Inn & Suites Imperial Beach San Diego

Mar Vista

United States

Joshua

includes taxes & fees

8 Nov - 9 Nov

A buffet with various food items, including omelets and other dishes, served in metal trays.

16. Holiday Inn Express San Diego South - Chula Vista by IHG

Chula Vista

United States

Daniel

includes taxes & fees

29 Nov - 30 Nov

A motel with a sign indicating amenities like Wi-Fi, TV, and pool.

17. Valli Hi Motel

San Ysidro

United States

Christian

includes taxes & fees

2 Nov - 3 Nov

A person sitting on a counter with a sign that reads "THERE'S GOOD LOOKIN'".

18. The Rambler Hotel

Chula Vista

United States

Neal

includes taxes & fees

1 Dec - 2 Dec

A historic building with ornate architecture, a reflective pond with lily pads, and palm trees.

19. Studio 6 Suites San Ysidro, CA -San Diego South Bay

San Ysidro

United States

Zach

includes taxes & fees

2 Nov - 3 Nov

A hotel room with a bed, a desk with a chair, a nightstand, and a wall-mounted TV displaying a sunset scene.

20. Hotel Palmeras Chula Vista

Chula Vista

United States

AHMAD

includes taxes & fees

2 Nov - 3 Nov

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Choose what matters most at spa hotels in South San Diego

Pool

Breakfast included

Top South San Diego Hotel Reviews

Wyndham San Diego Bayside

Wyndham San Diego Bayside

10/10 Excellent

"I felt welcomed! Amazing time and staff!"

The Dana on Mission Bay

The Dana on Mission Bay

8/10 Good

"The staff were warm, kind, and helpful throughout our stay, and we loved the nightly poolside movies. Unfortunately, the food at the Firefly was a letdown. The cocktails were weak, the flatbread pizza arrived so cold that the cheese hadn’t melted, and the Caesar salad was almost comical: a few strips of romaine with some croutons tossed on top. We were also disappointed that several amenities we’d been looking forward to were closed on Tuesday and Wednesday. The location is great and the property is beautiful, but overall it didn’t quite live up to my expectations."

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