Southeast Missouri Hotels

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Our top choices for Southeast Missouri hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,004 reviews)
"Very nice for overnight stay"
United States
Scott
The price is €109
includes taxes & fees
30 Apr - 1 May
Drury Inn & Suites Sikeston, MO

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,004 reviews)
"Great room, staff and breakfast! "
United States
Kenneth
The price is €103
includes taxes & fees
6 May - 7 May
Drury Plaza Hotel Cape Girardeau Conference Center

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (743 reviews)
"Very clean and staff was very nice"
United States
Nastassia
The price is €82
includes taxes & fees
13 Apr - 14 Apr
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (532 reviews)
"Great stay"
United States
grant
The price is €105
includes taxes & fees
10 May - 11 May
Hampton Inn Sikeston

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (887 reviews)
"Staff is Great , Room very clean and well stocked ."
United States
joan
The price is €106
includes taxes & fees
26 Apr - 27 Apr
Fairfield Inn & Suites by Marriott Poplar Bluff

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very good, (1,003 reviews)
"Great staff and nice accommodations "
United States
Lisa
The price is €58
includes taxes & fees
20 Apr - 21 Apr
Baymont Inn and Suites by Wyndham Farmington, MO

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,001 reviews)
"This was probably the cleanest hotel we have ever stayed in. The beds were also very comfortable. Staff was also friendly and helpful."
United States
Amber
The price is €101
includes taxes & fees
19 Apr - 20 Apr
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (173 reviews)
"Nearby Mexican restaurant, clean room, pleasant staff, good breakfast choices "
United States
Larry
The price is €88
includes taxes & fees
27 Apr - 28 Apr
Fairfield Inn & Suites by Marriott Cape Girardeau

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
8.0 out of 10, Very good, (1,002 reviews)
"Overall stay was convenient."
United States
Salman Mahmud
The price is €58
includes taxes & fees
13 Apr - 14 Apr
Motel 6 Poplar Bluff, MO

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1,004 reviews)
"My wife and I stay was absolutely lovely. "
United States
Chad
The price is €69
includes taxes & fees
27 Apr - 28 Apr
Pear Tree Inn Cape Girardeau West

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,007 reviews)
"Great food and pool. Clean and cozy. We will be back! "
United States
Leora
The price is €73
includes taxes & fees
3 May - 4 May
Drury Inn & Suites Jackson MO

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,002 reviews)
"Very nice folks who manage the hotel!!"
United States
Jane
The price is €88
includes taxes & fees
19 Apr - 20 Apr
Best Western Plus Sikeston I-55

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (816 reviews)
"Would stay again"
United States
David
The price is €89
includes taxes & fees
10 May - 11 May
Hampton Inn Poplar Bluff

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,009 reviews)
"Clean room, friendly staff, great breakfast. "
United States
jessica
The price is €95
includes taxes & fees
30 Apr - 1 May
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (1,003 reviews)
"Clean, comfortable room and great staff!"
United States
Kendra
The price is €101
includes taxes & fees
10 May - 11 May
Drury Inn & Suites Poplar Bluff

The Farmstead Hotel

The Farmstead Hotel
2.5 star property
Caruthersville
8.6 out of 10, Excellent, (536 reviews)
"Such a wonderful hotel! I highly recommend staying here. I’ve been there multiple times and I’ve never once been disappointed. "
United States
Alexus
The price is €92
includes taxes & fees
20 Apr - 21 Apr
The Farmstead Hotel

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (578 reviews)
"The hotel and room were very clean. It was in a quiet area. "
United States
Alice
The price is €99
includes taxes & fees
16 Apr - 17 Apr
Holiday Inn Express & Suites Perryville by IHG

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (70 reviews)
"Nice quiet hotel "
United States
Steven
The price is €106
includes taxes & fees
7 May - 8 May
Fairfield Inn & Suites by Marriott Sikeston

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
3.0 star property
Festus
8.0 out of 10, Very good, (956 reviews)
"All was great!"
United States
Laureen
The price is €87
includes taxes & fees
26 Apr - 27 Apr
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

Super 8 by Wyndham Potosi

Super 8 by Wyndham Potosi
2.0 star property
Potosi
7.0 out of 10, Good, (390 reviews)
"Room was clean, they are painting rooms, but not really updating the rooms. Maybe our room wasn't updated yet don't know. The lady at check in was great very friendly. The door to the outside had duck tape to keep it open, hopefully that is temporary. The stay was better than the first time we stayed. The 1st time bad odor in the hallway, that was gone this time which was an improvement."
United States
Cynthia
The price is €52
includes taxes & fees
20 Apr - 21 Apr
Super 8 by Wyndham Potosi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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