Southeast Missouri Hotels
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Our top choices for Southeast Missouri hotels
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,007 reviews)
"This hotel was so clean and comfy! The breakfast was awesome too!"
Jamie
The price is €87
includes taxes & fees
2 Aug - 3 Aug
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (83 reviews)
The price is €125
includes taxes & fees
13 Aug - 14 Aug
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (207 reviews)
"The room was clean, the staff was extremely helpful with our check in!"
Travis
The price is €92
includes taxes & fees
30 Jul - 31 Jul
Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (150 reviews)
"This is a clean, quiet, well designed hotel."
Kendra
The price is €93
includes taxes & fees
4 Aug - 5 Aug
The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (625 reviews)
"Good, quiet and clean place to stay."
Gary
The price is €113
includes taxes & fees
3 Aug - 4 Aug
Perryville RV Resort
Perryville RV ResortPerryville
10.0 out of 10, Exceptional, (1 review)
"We had a amazing time it was our 4 yr anniversary"
Von
The price is €74
includes taxes & fees
16 Jul - 17 Jul
Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
9.2 out of 10, Wonderful, (606 reviews)
"Breakfast was good nice beds very nice stay"
scott
The price is €92
includes taxes & fees
21 Jul - 22 Jul
Deerfield Inn & Suites Steele Near Blytheville I 55
Deerfield Inn & Suites Steele Near Blytheville I 55Steele
7.0 out of 10, Good, (4 reviews)
"Love it, very peaceful! What else want from me"
Mary
The price is €49
includes taxes & fees
16 Jul - 17 Jul
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,018 reviews)
"Drury Hotels are great. Love the amenities, service, and nice rooms."
Marilyn
The price is €99
includes taxes & fees
9 Aug - 10 Aug
Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.6 out of 10, Excellent, (374 reviews)
"Convenient place to stay at in the area."
JOAQUIN
The price is €94
includes taxes & fees
8 Aug - 9 Aug
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,017 reviews)
"Great place!"
Jennifer
The price is €112
includes taxes & fees
19 Jul - 20 Jul
Current River Inn
Current River InnVan Buren
8.2 out of 10, Very good, (187 reviews)
"This was the cutest little place to stay. The people are friendly, room was clean, and it was safe. I would stay here again. "
Jennifer
The price is €103
includes taxes & fees
14 Jul - 15 Jul
Arcadia Academy
Arcadia AcademyArcadia
9.4 out of 10, Exceptional, (13 reviews)
"We enjoyed ourselves we've been to plenty of places but we had a great excellent time people the room the food and it was great we will be back¡!!!"
John
The price is €123
includes taxes & fees
14 Jul - 15 Jul
Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (898 reviews)
"Very clean room and excellent breakfast options."
Christie
The price is €96
includes taxes & fees
19 Jul - 20 Jul
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (99 reviews)
"Great stay, kind staff, very clean property."
Joni
The price is €109
includes taxes & fees
19 Jul - 20 Jul
Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (935 reviews)
"Breakfast was very good. Room was clean & bed comfortable"
Larry
The price is €100
includes taxes & fees
2 Aug - 3 Aug
Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (478 reviews)
"Only stayed one night, no complaints"
Zachary
The price is €94
includes taxes & fees
26 Jul - 27 Jul
Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MOFarmington
8.0 out of 10, Very good, (1,024 reviews)
"It was a great stay"
Daisy
The price is €56
includes taxes & fees
13 Aug - 14 Aug
Hampton Inn By Hilton Dexter
Hampton Inn By Hilton DexterDexter
9.8 out of 10, Exceptional, (48 reviews)
"Great place to stay"
Lauren
The price is €96
includes taxes & fees
26 Jul - 27 Jul
Super 8 By Wyndham Marston
Super 8 By Wyndham MarstonMarston
8.0 out of 10, Very good, (68 reviews)
"Clean room, The receptionist very friendly, good parking."
Temera
The price is €70
includes taxes & fees
14 Jul - 15 Jul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southeast Missouri
Cabin
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (83 reviews)
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Stay near popular Southeast Missouri attractions
Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to Walnut Hollow Lake.
Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews
Drury Inn & Suites Sikeston, MO
10/10 Excellent
More cheap stays in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is €56 per night from 13 Aug to 14 Aug
€56
13 Aug - 14 Aug
includes taxes & fees
8/10 Very good! (1,024 reviews)
4 Star Hotels
1 properties
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- Allenville Hotels
- Arcadia Hotels
- Belleview Hotels
- Black Hotels
- Bloomsdale Hotels
- Bonne Terre Hotels
- Broseley Hotels
- Bunker Hotels
- Caledonia Hotels
- Cape Girardeau Hotels
- Clearwater Hotels
- Desloge Hotels
- St. Francois County Hotels
- Hotels with Pool in Dexter
- Dexter Hotels
- Wyndham Hotels in Doe Run
- Hotels near eDen Spa & Salon
- Ellington Hotels
- Eminence Hotels
- Fredericktown Hotels
- Fruitland Hotels
- Gordonville Hotels
- Historic Hotels in Ironton
- Ironton Hotels
- Lesterville Hotels
- Marble Hill Hotels
- Cabin Rentals in Middle Brook
- Hilton Hotels in Middle Brook
- Hotels near National Shrine of Our Lady of the Miraculous Medal
- Perryville Hotels
- Poplar Bluff Hotels
- Motel 6 Hotels in Southeast Missouri
- Hotels near Southeast Missouri State University
- B&B in St Mary
- Ste Genevieve Hotels
- Aimbridge Hospitality Hotels in Tiff
- Tiff Hotels
- Van Buren Hotels
- Arcadia Holidays
- Visit Bernie
- Visit Bloomsdale
- Visit Bonne Terre
- Cave Spring Park
- Dexter Holidays
- Visit Doniphan
- Eden Spa & Salon
- Visit Fredericktown
- Visit Grandin
- Johnson's Shut-ins State Park
- K Bridge Recreation Area
- Visit Old Appleton
- Visit Ozora
- Visit Park Hills
- Visit Qulin
- Rocky Falls
- Van Buren Holidays
- Visit Van Buren
- Walnut Hollow Lake
- Visit Wappapello
- Washington State Park
- Ace New Zealand Rental Cars in Doe Run
- Ada Rental Cars in New Offenburg
- Addcar rental Rental Cars in Fruitland
- Apex Car Rentals Rental Cars in Southeast Missouri
- Auto Rent Rental Cars in Black
- Car hire Black
- Goldcar Key’n Go Rental Cars in Cherryville
- Island Car Rentals Rental Cars in Ellington
- Ok Mobility Rental Cars in Grandin
- Priceless Car Rental Rental Cars in Black
- Sicily By Car Rental Cars in Delta
