Photo by Visit Greenville, South Carolina

Upstate South Carolina Hotel Guide - Business Hotels in Upstate South Carolina, South Carolina

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Upstate South Carolina Business Hotels

Top Upstate South Carolina Business Hotels

Free daily full breakfast
Holiday Inn Express Gaffney by IHG

Holiday Inn Express Gaffney by IHG

2.5 star property
Gaffney
8.6 out of 10, Excellent, (406)
"Great place to stay"
United States
Timothy
The price is €79
includes taxes & fees
23 Nov - 24 Nov
Holiday Inn Express Gaffney by IHG
Free daily on-the-go breakfast
Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

2.5 star property
Downtown
8.0 out of 10, Very good, (659)
"Ok hotel for a quick stay "
United States
Lori
The price is €77
includes taxes & fees
7 Dec - 8 Dec
Quality Inn Seneca Clemson Area US-123
Exterior
DoubleTree by Hilton Greenville Woodruff Road

DoubleTree by Hilton Greenville Woodruff Road

3.0 star property
Greenville
9.4 out of 10, Exceptional, (1004)
"Staff and room are top notch!"
United States
Doug
The price is €100
includes taxes & fees
23 Nov - 24 Nov
DoubleTree by Hilton Greenville Woodruff Road
Balcony
Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
Seneca
9.4 out of 10, Exceptional, (204)
"Beautiful clean hotel. Staff was very welcoming. Breakfast area was very clean with many options. The river view is so beautiful. "
United States
Linda
The price is €114
includes taxes & fees
23 Nov - 24 Nov
Fairfield Inn & Suites Seneca Clemson Univ Area
Free daily continental breakfast
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2.0 star property
Anderson
7.8 out of 10, Good, (1006)
"Wonderful for families—safe, quiet, and the staff made us feel at home."
United States
Jessica
The price is €60
includes taxes & fees
19 Nov - 20 Nov
Days Inn by Wyndham Anderson
Lobby
Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson

2.0 star property
Anderson
8.2 out of 10, Very good, (1002)
"Room was clean, staff was nice! "
United States
Martina
The price is €76
includes taxes & fees
23 Nov - 24 Nov
Microtel Inn & Suites by Wyndham Anderson/Clemson
Free daily continental breakfast
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 star property
Greenville
9.2 out of 10, Wonderful, (1398)
"Good hotel"
United States
magadan
The price is €79
includes taxes & fees
23 Nov - 24 Nov
Best Western Plus Greenville I-385 Inn & Suites
Lobby lounge
Inn @ Clemson

Inn @ Clemson

2.5 star property
Clemson
8.0 out of 10, Very good, (1004)
"Very nice staff and great place to stay"
United States
Kimberley
Inn @ Clemson
Gazebo
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

3.0 star property
Greenville
8.6 out of 10, Excellent, (47)
"Courteous staff and very clean ammentities "
United States
David
The price is €67
includes taxes & fees
1 Dec - 2 Dec
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
Exterior
Woodspring Suites Greenville Airport

Woodspring Suites Greenville Airport

2.5 star property
Greenville
8.2 out of 10, Very good, (283)
"Clean room, friendly staff, I would definitely stay here again!"
United States
Melissa
The price is €75
includes taxes & fees
18 Nov - 19 Nov
Woodspring Suites Greenville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Upstate South Carolina Hotel Reviews

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123

10/10 Excellent
"Clean room w fridge and microwave Comfy bed"
Bonnie 1-night trip
Posted 2 days ago
Quality Inn Seneca Clemson Area US-123

Explore a world of travel with Expedia

Frequently asked questions

How much do business-friendly hotels in Upstate South Carolina cost?
You can expect to pay between and per night for business-friendly hotels in Upstate South Carolina. Terrific deals on stays that are suitable for work-related travellers are a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Upstate South Carolina?
That depends on your destination in Upstate South Carolina. Lots of business travellers to Greenville choose Homewood Suites by Hilton Greenville Downtown. This 3-stars property has a barbecue grill and a swimming pool. SpringHill Suites by Marriott Greenville Downtown is another excellent option if you're arranging a meeting or working remotely in Greenville. A swimming pool and a barbecue grill are some of the useful amenities at this 2.5-stars retreat. You can choose from multiple business-friendly hotels in Upstate South Carolina that have a total average guest review rating of .
How many business-friendly hotels are there in Upstate South Carolina?
When your next meeting or conference takes you someplace in Upstate South Carolina, you'll have business-friendly hotels to choose from.
What are the best cheap business-friendly hotels in Upstate South Carolina?
That depends on which corner of Upstate South Carolina work is taking you. If you're headed to Greenville, SpringHill Suites by Marriott Greenville Downtown combines affordability with business-friendly amenities. A terrace and a barbecue grill are a couple of its many conveniences. On your way to Spartanburg? Look up Tru by Hilton Spartanburg. WiFi and a playground help make this cheaper property a favourite with corporate visitors. Business-friendly hotels start at just per night, so your next work trip doesn't have to stretch your finances. There are loads of fun and free things to do wherever you're headed in Upstate South Carolina. If business is taking you to Greenville, try to find time to swing by Greenville County Museum of Art. You can also go sightseeing without spending a dime in Spartanburg. Spartanburg Regional Hospital is one of the most popular free attractions here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the top business-friendly motels in Upstate South Carolina?
Expedia's business-friendly motels in Upstate South Carolina come with amenities that are the ideal mix of work and play. One of our best options is Urban Boutique Hotel, BW Signature Collection in Greenville. Located around 3 kilometres northeast of the downtown area, WiFi and front desk services are the start of its many conveniences. Another stay that appeals to corporate travellers is Days Inn by Wyndham Greenville. It's approximately 8 kilometres east of the centre of Greenville and features a swimming pool, front desk services and more.There are a ton of things to keep you entertained when you're not hard at work in Greenville. The Peace Centre and Frankie's Fun Park should be on your sightseeing checklist.
Are there any family-friendly hotels in Upstate South Carolina that are also business friendly?
You'll discover some terrific family-friendly hotels that are also business friendly in Upstate South Carolina. If you're on your way to Greenville, take a look at SpringHill Suites by Marriott Greenville Downtown. It comes with useful amenities like complimentary breakfast and WiFi and has a 2.5-stars rating. Another option to consider is Hampton Inn & Suites Greenville-Downtown-RiverPlace. This 2.5-stars stay in Greenville is perfect for both leisure and business travellers and offers complimentary breakfast, room service and more. Greenville offers loads of family-friendly attractions when you're ready to discover the sights. Frankie's Fun Park and Greenville Zoo will keep your crew entertained.
Are there any 5-star business-friendly hotels in Upstate South Carolina?
In Upstate South Carolina, 5-star business-friendly hotels are difficult to come by. However, there are some 4-star properties that cater to corporate travellers. If you're making tracks to Greenville for work, base yourself at The Westin Poinsett Greenville. It comes with handy amenities including pillow top mattresses and room service. Or, put your laptop down and feet up at Greenville Marriott, also in Greenville. Take advantage of its conveniences including a swimming pool and pillow top mattresses.
Why book your business-friendly hotel in Upstate South Carolina with Expedia?
We're here to help you find a suitable business-friendly hotel when work takes you on the road. From free parking and WiFi to gyms and on-site restaurants, our properties have the things you'll need to get the job done.
How can I find cheap business-friendly hotels in Upstate South Carolina?
When work takes you to Upstate South Carolina, our "business friendly" filter will help you find the right hotel. From WiFi to workspaces and meeting rooms, they come with the amenities you need for a productive and comfortable stay. You can also narrow your search by your preferred star rating and budget to see the most affordable properties.
What is there to do in Upstate South Carolina near my business-friendly hotel?
The most important travel accessory for your Upstate South Carolina business journey is a good itinerary for your free time! The Peace Centre, Greenville Zoo and The Children's Museum of the Upstate are some of the well-known sights if you're staying in Greenville. Spartanburg also has plenty of superb attractions, such as Spartanburg Memorial Auditorium, Spartanburg Regional History Museum and Chapman Cultural Centre.