Wykoff Hotels

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Our top choices for Wykoff hotels

Stone Mill Hotel & Suites

Stone Mill Hotel & Suites
3.0 star property
Lanesboro
9.2 out of 10, Wonderful, (663)
"Great service, location"
United States
Eric
The price is €96
includes taxes & fees
13 Jan - 14 Jan 2026
Stone Mill Hotel & Suites

Country Lodge inn

Country Lodge inn
2.0 star property
Harmony
9.0 out of 10, Wonderful, (39)
"Old motel but clean, with friendly owners."
United States
Fred
The price is €130
includes taxes & fees
1 Jan - 2 Jan 2026
Country Lodge inn

Country Trails Inn & Suites

Country Trails Inn & Suites
2.0 star property
Preston
9.4 out of 10, Exceptional, (102)
"Great desk host, nice property, comfortable rooms, nice breakfast & dining room within walking from Casey’s gas & market. "
United States
Nancy
The price is €107
includes taxes & fees
1 Jan - 2 Jan 2026
Country Trails Inn & Suites

White Valley Motel

White Valley Motel
2.5 star property
St. Charles
5.6 out of 10, (128)
"Very nice owner i wil come back again thank you.. "
United States
Rolando
The price is €65
includes taxes & fees
1 Jan - 2 Jan 2026
White Valley Motel

Americas Best Value Inn & Suites Spring Valley

Americas Best Value Inn & Suites Spring Valley
2.0 star property
Spring Valley
8.2 out of 10, Very good, (435)
"The place was very clean, very quiet and the staff was extremely helpful. We will be back"
United States
Melissa
The price is €83
includes taxes & fees
1 Jan - 2 Jan 2026
Americas Best Value Inn & Suites Spring Valley

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (894)
"Room was clean and comfortable Staff courteous Comfortable beds Great restaurant"
United States
Matney
The price is €79
includes taxes & fees
31 Jan - 1 Feb 2026
Hotel Indigo Rochester – Mayo Clinic Area by IHG

America's Stay Inn Stewartville

America's Stay Inn Stewartville
2.5 star property
Stewartville
8.0 out of 10, Very good, (419)
"Room was nicer and furnished better than most high end places I’ve stayed at. It’s a small hotel on a busy road, but comfortable bed and clean."
Canada
Robert
America's Stay Inn Stewartville

Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1000)
"Clean room, clean hotel, friendly staff Would stay here again."
United States
Chee
The price is €72
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express Rochester South - Mayo Area by IHG

Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
Rochester
9.4 out of 10, Exceptional, (333)
"Very good accommodations at a wonderful price. "
United States
David
The price is €69
includes taxes & fees
11 Jan - 12 Jan 2026
Spark by Hilton Rochester South

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1001)
"We had a wonderful stay!"
United States
Sarah
The price is €79
includes taxes & fees
24 Jan - 25 Jan 2026
Hampton Inn Rochester-South

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.2 out of 10, Good, (1027)
"Staff was courteous and breakfast was well stocked."
United States
Doug
The price is €70
includes taxes & fees
2 Jan - 3 Jan 2026
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.2 out of 10, Very good, (1154)
"Check in was fast, room, and pool area were great, its connected to the crooked pint, making dining convenient. "
United States
Brian
The price is €73
includes taxes & fees
3 Jan - 4 Jan 2026
AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester

AmericInn by Wyndham Rochester
2.0 star property
Rochester
8.8 out of 10, Excellent, (1002)
"Enjoyed our stay, rated breakfast as a erage as we did not try it."
United States
jeanne
AmericInn by Wyndham Rochester

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park
9.2 out of 10, Wonderful, (773)
"Clean room and housekeeping service was excellent"
United States
Dawn
The price is €82
includes taxes & fees
2 Jan - 3 Jan 2026
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
Rochester
8.2 out of 10, Very good, (798)
"This hotel was"
United States
Sheila
The price is €92
includes taxes & fees
12 Jan - 13 Jan 2026
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester
8.8 out of 10, Excellent, (856)
"Yes the workers are amazing "
United States
Luciana
The price is €105
includes taxes & fees
8 Jan - 9 Jan 2026
Hilton Garden Inn Rochester Downtown, MN

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (971)
"The staff was very friendly and the room spotless. "
United States
Judith
The price is €113
includes taxes & fees
2 Jan - 3 Jan 2026
EVEN Hotel Rochester - Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
Kutzky Park
8.8 out of 10, Excellent, (766)
"Clean room, friendly staff. The only minus is the lighting in the bathroom, way too dim. "
United States
Stacy
The price is €107
includes taxes & fees
2 Jan - 3 Jan 2026
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
Rochester
9.6 out of 10, Exceptional, (887)
"Great stay,clean and friendly"
United States
Janet
The price is €116
includes taxes & fees
2 Jan - 3 Jan 2026
Home2 Suites by Hilton Rochester Mayo Clinic Area

Country Inn & Suites Rochester South Mayo Clinic

Country Inn & Suites Rochester South Mayo Clinic
3.0 star property
Rochester
8.4 out of 10, Very good, (1002)
"Very friendly staff; clean, comfortable room. "
United States
Colleen
The price is €95
includes taxes & fees
31 Jan - 1 Feb 2026
Country Inn & Suites Rochester South Mayo Clinic
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Where is the best place to stay in Wykoff?
Located 24 mi (38.6 km) from the heart of Wykoff, Kahler Grand Hotel is a top choice for your stay, based on our traveller data. Two other choices for your trip to the area are Kahler Inn and Suites - Mayo Clinic Area and Hampton Inn Rochester-South. See all available top hotels, or vacation rentals in Wykoff.
What are some of the best holiday rentals that Wykoff has to offer?
Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom: This holiday home rental outside of Wykoff offers a patio, a garden and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of games in this rental home to help you unwind. See all vacation rentals in Wykoff.
If I need to cancel my hotel reservation in Wykoff, will I receive a refund?
Yes! You'll find that most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Wykoff.
How is it staying in Wykoff?
Visitors can enjoy all that Wykoff has to offer, including its museums. There are 322 hotels and other accommodation options in the surrounding area. Find out more about Wykoff.
What should I see while I'm in Wykoff?
A favourite place to visit is Ed's Museum. You'll also find Forestville Mystery Cave State Park and Four Daughters Vineyard & Winery in the area. Take a look at what more there is to see and do in Expedia's Wykoff guide.
What's the weather like in Wykoff?
The hottest months are usually July and August, with an average temperature of 20°C, while the coldest months are January and February, with an average of -5°C. The snowiest months in Wykoff are January, March, February and April, with each month seeing an average of 20 cm of snowfall.

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