Cheap flights from Panama starting at €154

View €154 flight on Tue, 16 Sep 2025Opens in a new window

Popular airlines from Panama

  • United

    United

  • American Airlines

    American Airlines

  • KLM

    KLM

  • Delta

    Delta

  • Avianca

    Avianca

  • Air France

    Air France

  • Air Europa

    Air Europa

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Cheapest flights from Panama

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

Aeromexico
Fri, 12 Dec - Tue, 23 Dec
PTY
Panama City
CUN
Cancun
€275 Return, found 1 day ago
€275
Return
found 1 day ago
Select Aeromexico flight, departing Fri, 12 Dec from Panama City to Cancun, returning Tue, 23 Dec, priced at €275 found 1 day ago
Copa
Fri, 22 Aug - Thu, 28 Aug
PTY
Panama City
MDE
Medellin
€277 Return, found 2 days ago
€277
Return
found 2 days ago
Select Copa flight, departing Fri, 22 Aug from Panama City to Medellin, returning Thu, 28 Aug, priced at €277 found 2 days ago
Copa
Fri, 12 Sep - Tue, 16 Sep
PTY
Panama City
MDE
Medellin
€279 Return, found 4 hours ago
€279
Return
found 4 hours ago
Select Copa flight, departing Fri, 12 Sep from Panama City to Medellin, returning Tue, 16 Sep, priced at €279 found 4 hours ago
Copa
Fri, 22 Aug - Thu, 28 Aug
PTY
Panama City
MDE
Medellin
€311 Return, found 2 days ago
€311
Return
found 2 days ago
Select Copa flight, departing Fri, 22 Aug from Panama City to Medellin, returning Thu, 28 Aug, priced at €311 found 2 days ago
Copa
Fri, 12 Sep - Tue, 16 Sep
PTY
Panama City
MDE
Medellin
€313 Return, found 4 hours ago
€313
Return
found 4 hours ago
Select Copa flight, departing Fri, 12 Sep from Panama City to Medellin, returning Tue, 16 Sep, priced at €313 found 4 hours ago
Delta
Wed, 29 Oct - Tue, 4 Nov
PTY
Panama City
MIA
Miami
€324 Return, found 4 days ago
€324
Return
found 4 days ago
Select Delta flight, departing Wed, 29 Oct from Panama City to Miami, returning Tue, 4 Nov, priced at €324 found 4 days ago
Copa
Fri, 22 Aug - Thu, 28 Aug
PTY
Panama City
MDE
Medellin
€340 Return, found 2 days ago
€340
Return
found 2 days ago
Select Copa flight, departing Fri, 22 Aug from Panama City to Medellin, returning Thu, 28 Aug, priced at €340 found 2 days ago
Copa
Fri, 12 Sep - Tue, 16 Sep
PTY
Panama City
MDE
Medellin
€343 Return, found 4 hours ago
€343
Return
found 4 hours ago
Select Copa flight, departing Fri, 12 Sep from Panama City to Medellin, returning Tue, 16 Sep, priced at €343 found 4 hours ago
avianca
Fri, 22 Aug - Thu, 28 Aug
PTY
Panama City
MDE
Medellin
€358 Return, found 2 days ago
€358
Return
found 2 days ago
Select avianca flight, departing Fri, 22 Aug from Panama City to Medellin, returning Thu, 28 Aug, priced at €358 found 2 days ago
American Airlines
Sat, 13 Sep - Sun, 14 Sep
PTY
Panama City
MIA
Miami
€398 Return, found 4 days ago
€398
Return
found 4 days ago
Select American Airlines flight, departing Sat, 13 Sep from Panama City to Miami, returning Sun, 14 Sep, priced at €398 found 4 days ago
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