Cheap flights from Panama starting at €129

View €129 flight on Tue, 16 Dec 2025Opens in a new window

Popular airlines from Panama

  • Avianca

    Avianca

  • United

    United

  • American Airlines

    American Airlines

  • Copa

    Copa

  • Delta

    Delta

  • Aeromexico

    Aeromexico

  • Turkish Airlines

    Turkish Airlines

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Cheapest flights from Panama

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Tue, 16 Dec - Sun, 21 Dec
PTY
Panama City
MDE
Medellin
€243 Return, found 4 days ago
€243
Return
found 4 days ago
Select avianca flight, departing Tue, 16 Dec from Panama City to Medellin, returning Sun, 21 Dec, priced at €243 found 4 days ago
avianca
Tue, 16 Dec - Sun, 21 Dec
PTY
Panama City
MDE
Medellin
€252 Return, found 4 days ago
€252
Return
found 4 days ago
Select avianca flight, departing Tue, 16 Dec from Panama City to Medellin, returning Sun, 21 Dec, priced at €252 found 4 days ago
Copa
Thu, 13 Nov - Sun, 16 Nov
PTY
Panama City
BOG
Bogotá
€305 Return, found 20 hours ago
€305
Return
found 20 hours ago
Select Copa flight, departing Thu, 13 Nov from Panama City to Bogotá, returning Sun, 16 Nov, priced at €305 found 20 hours ago
Copa
Wed, 24 Dec - Wed, 31 Dec
PTY
Panama City
BOG
Bogotá
€305 Return, found 4 days ago
€305
Return
found 4 days ago
Select Copa flight, departing Wed, 24 Dec from Panama City to Bogotá, returning Wed, 31 Dec, priced at €305 found 4 days ago
Copa
Thu, 13 Nov - Sun, 16 Nov
PTY
Panama City
BOG
Bogotá
€315 Return, found 20 hours ago
€315
Return
found 20 hours ago
Select Copa flight, departing Thu, 13 Nov from Panama City to Bogotá, returning Sun, 16 Nov, priced at €315 found 20 hours ago
avianca
Tue, 16 Dec - Sun, 21 Dec
PTY
Panama City
MDE
Medellin
€325 Return, found 4 days ago
€325
Return
found 4 days ago
Select avianca flight, departing Tue, 16 Dec from Panama City to Medellin, returning Sun, 21 Dec, priced at €325 found 4 days ago
Copa
Thu, 13 Nov - Sun, 16 Nov
PTY
Panama City
BOG
Bogotá
€327 Return, found 20 hours ago
€327
Return
found 20 hours ago
Select Copa flight, departing Thu, 13 Nov from Panama City to Bogotá, returning Sun, 16 Nov, priced at €327 found 20 hours ago
American Airlines
Thu, 19 Feb - Wed, 25 Feb
PTY
Panama City
MCO
Orlando
€478 Return, found 20 hours ago
€478
Return
found 20 hours ago
Select American Airlines flight, departing Thu, 19 Feb from Panama City to Orlando, returning Wed, 25 Feb, priced at €478 found 20 hours ago
United
Thu, 19 Feb - Wed, 25 Feb
PTY
Panama City
MCO
Orlando
€482 Return, found 20 hours ago
€482
Return
found 20 hours ago
Select United flight, departing Thu, 19 Feb from Panama City to Orlando, returning Wed, 25 Feb, priced at €482 found 20 hours ago
Delta
Fri, 21 Nov - Tue, 25 Nov
PTY
Panama City
MIA
Miami
€639 Return, found 6 days ago
€639
Return
found 6 days ago
Select Delta flight, departing Fri, 21 Nov from Panama City to Miami, returning Tue, 25 Nov, priced at €639 found 6 days ago
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