
Popular airlines from Chicago O'Hare Intl. Airport (ORD) to Des Moines International Airport (DSM)
- Delta
Delta
- American Airlines
American Airlines
- Southwest Airlines
Southwest Airlines
- United
United
- Frontier Airlines
Frontier Airlines
- Plan, book, fly with confidence
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Cheap flights from Chicago to Des Moines (ORD-DSM)
Prices were available within the past 7 days and start at €91 for one-way flights and €163 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, 11 Sep - Sun, 14 Sep
ORD
Chicago
DSM
Des Moines
€163 Return, found 1 day ago
€163
Return
found 1 day ago

Wed, 27 Aug - Sat, 30 Aug
ORD
Chicago
DSM
Des Moines
€192 Return, found 6 days ago
€192
Return
found 6 days ago

Sat, 6 Sep - Sun, 7 Sep
ORD
Chicago
DSM
Des Moines
€197 Return, found 6 days ago
€197
Return
found 6 days ago

Wed, 27 Aug - Sat, 30 Aug
ORD
Chicago
DSM
Des Moines
€201 Return, found 6 days ago
€201
Return
found 6 days ago

Thu, 11 Sep - Sun, 14 Sep
ORD
Chicago
DSM
Des Moines
€201 Return, found 1 day ago
€201
Return
found 1 day ago

Wed, 27 Aug - Sat, 30 Aug
ORD
Chicago
DSM
Des Moines
€209 Return, found 6 days ago
€209
Return
found 6 days ago

Thu, 11 Sep - Sun, 14 Sep
ORD
Chicago
DSM
Des Moines
€215 Return, found 1 day ago
€215
Return
found 1 day ago

Wed, 27 Aug - Sat, 30 Aug
ORD
Chicago
DSM
Des Moines
€222 Return, found 6 days ago
€222
Return
found 6 days ago

Wed, 27 Aug - Sat, 30 Aug
ORD
Chicago
DSM
Des Moines
€230 Return, found 6 days ago
€230
Return
found 6 days ago

Thu, 11 Sep - Sun, 14 Sep
ORD
Chicago
DSM
Des Moines
€241 Return, found 1 day ago
€241
Return
found 1 day ago
Find the cheapest month to fly from Chicago (ORD) to Des Moines (DSM)
October is typically the cheapest month to fly
From €118 - €252 per traveller.
Graph displaying average flight prices per month
Origin airport | O'Hare Intl. |
Destination airport | Des Moines Intl. |
Return price | €163 |
Distance | 476 km |
Average flight time | 1 hour 26 mins |
Perfect flights from Chicago to Des Moines
Embark on an unforgettable journey without breaking the bank with Expedia's incredible deals on cheap flights from Chicago to Des Moines. Whether you're aching for a romantic escape with your partner, craving an adventurous solo expedition, or yearning to immerse yourself in the local history and culture, we've got you covered.
Picture yourself strolling through the streets of Des Moines, surrounded by breathtaking architecture and absorbing the vibrant atmosphere of this captivating city. Indulge in the mouth-watering local specialties, from tantalizing street food to exquisite fine dining. With Expedia, you can experience all of this and more, without sacrificing your budget.
Our flexible O'Hare Intl. to Des Moines Intl. ticket options cater to your travel preferences, with incredible one-way fares from €91 and roundtrip prices from €163. Whether you're planning a short city break or a longer adventure, our dynamic pricing ensures that you find the best deals for your journey.
But the magic doesn't stop there. Expedia offers a range of partner services to enhance your trip. Rent a car at Des Moines Intl. and explore Des Moines and its surrounding areas at your own pace. Discover hidden gems off the beaten path, and create unforgettable memories. We also provide a handpicked selection of accommodations, from charming bed and breakfasts to luxury hotels, ensuring that you have a comfortable and memorable stay.
Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support are designed to make your travel experience seamless and stress-free. So, why wait? Book your ORD to DSM travel arrangements today and embark on the journey of a lifetime in Des Moines.
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Top Routes from Chicago
- Chicago to Newark Liberty Intl. Airport (ORD - EWR)
- Chicago to New York (ORD - LGA)
- Chicago to Fort Lauderdale (ORD - FLL)
- Chicago to Honolulu (ORD - HNL)
- Chicago to New York (ORD - JFK)
- Chicago to Dublin (ORD - DUB)
- Chicago to Tokyo (ORD - NRT)
- Chicago to Shannon (ORD - SNN)
- Chicago to New Orleans (ORD - MSY)
- Chicago to Nashville (ORD - BNA)
- Chicago to London (ORD - LHR)
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