Des Moines Hotel Guide - Business Hotels in Des Moines, Iowa

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Des Moines Business Hotels

Tonight
24 Dec - 25 Dec
Tomorrow
25 Dec - 26 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for Des Moines business-friendly hotels

Lobby
La Quinta Inn & Suites by Wyndham Des Moines West Clive

La Quinta Inn & Suites by Wyndham Des Moines West Clive

La Quinta Inn & Suites by Wyndham Des Moines West Clive
3.0 star property
Clive
8.6 out of 10, Excellent, (1005)
"Great place to stay! "
United States
Kirsten
The price is €62
includes taxes & fees
11 Jan - 12 Jan 2026
La Quinta Inn & Suites by Wyndham Des Moines West Clive
Lobby
Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West

Fairfield Inn and Suites by Marriott Des Moines West
2.5 star property
West Des Moines
9.0 out of 10, Wonderful, (1006)
"Room was clean, staff was courteous and the bed was comfortable. "
United States
Craig
The price is €79
includes taxes & fees
1 Jan - 2 Jan 2026
Fairfield Inn and Suites by Marriott Des Moines West
Free daily buffet breakfast
Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines

Drury Inn & Suites West Des Moines
3.0 star property
West Des Moines
9.4 out of 10, Exceptional, (1001)
"A great place to stay"
United States
Carol
The price is €95
includes taxes & fees
30 Dec - 31 Dec
Drury Inn & Suites West Des Moines
Deluxe Room, 2 Queen Beds, Non Smoking
Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport
2.0 star property
Greater South Side
8.6 out of 10, Excellent, (1692)
"Breakfast was good and parking was close and snow removed."
United States
Deborah
The price is €60
includes taxes & fees
1 Jan - 2 Jan 2026
Days Inn & Suites by Wyndham Des Moines Airport
Exterior
Holiday Inn Express & Suites Des Moines Downtown by IHG

Holiday Inn Express & Suites Des Moines Downtown by IHG

Holiday Inn Express & Suites Des Moines Downtown by IHG
2.5 star property
Downtown Des Moines
9.2 out of 10, Wonderful, (975)
"Great room, good breakfast. "
United States
Jason
The price is €85
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express & Suites Des Moines Downtown by IHG
Indoor pool
Country Inn & Suites by Radisson, Des Moines West, IA

Country Inn & Suites by Radisson, Des Moines West, IA

Country Inn & Suites by Radisson, Des Moines West, IA
3.0 star property
Clive
8.8 out of 10, Excellent, (1004)
"Was a great stay and great price. "
United States
Roger
The price is €76
includes taxes & fees
30 Dec - 31 Dec
Country Inn & Suites by Radisson, Des Moines West, IA
Exterior
Comfort Inn & Suites West Des Moines

Comfort Inn & Suites West Des Moines

Comfort Inn & Suites West Des Moines
2.5 star property
West Des Moines
8.8 out of 10, Excellent, (576)
"Convenient location"
United States
Todd
The price is €80
includes taxes & fees
25 Dec - 26 Dec
Comfort Inn & Suites West Des Moines
Lobby
Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport
2.5 star property
Southwestern Hills
9.4 out of 10, Exceptional, (1167)
"Convenient location to restaurants"
United States
Sally
The price is €82
includes taxes & fees
20 Jan - 21 Jan 2026
Baymont by Wyndham Des Moines Airport
Premium bedding, desk, iron/ironing board, free WiFi
Hyatt Place West Des Moines Jordan Creek

Hyatt Place West Des Moines Jordan Creek

Hyatt Place West Des Moines Jordan Creek
3.0 star property
West Des Moines
9.2 out of 10, Wonderful, (1001)
"The hotel was very clean and close to shopping and restaurants."
United States
Janelle
The price is €94
includes taxes & fees
30 Dec - 31 Dec
Hyatt Place West Des Moines Jordan Creek
Indoor spa tub
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston
2.5 star property
Johnston
8.8 out of 10, Excellent, (1794)
"The breakfast and coffee was absolutely amazing. "
United States
Brenda
The price is €84
includes taxes & fees
7 Jan - 8 Jan 2026
Stoney Creek Hotel Des Moines - Johnston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Des Moines Hotel Reviews

Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

10/10 Excellent
"Liked the hot tub even though there were lots of ants crawling around the outside of it"
Michael 1-night trip
Posted 3 days ago
Stoney Creek Hotel Des Moines - Johnston

Frequently asked questions

How much do business-friendly hotels in Des Moines cost?
You'll pay between €60 and €95 per night for business-friendly hotels in Des Moines. Top deals on properties that are suitable for corporate travellers as just a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Des Moines?
Pick from multiple business-friendly hotels in Des Moines that have a total average guest review rating of 8.9. Surety Hotel is a favourite with many corporate travellers. This 4-stars property comes with amenities such as individually decorated rooms and an outdoor entertainment area. Staybridge Suites Des Moines Downtown, an IHG Hotel is another highly rated option. It has a 3-stars rating and conveniences including a barbecue grill and a swimming pool.
How many business-friendly hotels are there in Des Moines?
When work takes you to Des Moines, you'll have 113 business-friendly hotels to choose from. These stays offer a good location with the conveniences corporate travellers need.
What are the best cheap business-friendly hotels in Des Moines?
Reduce expenses on your work trip to Des Moines by choosing one of our business-friendly hotels that start at €60 per night. One affordable property is Fairfield Inn & Suites Des Moines Altoona, which comes with amenities like a swimming pool and a tennis court. Sleep Inn & Suites Ankeny - Des Moines is another sought-after pick for corporate travellers on a strict budget. It offers a swimming pool and a spa tub. When it's time to do some sightseeing in Des Moines, add a few fabulous free attractions to your work travel agenda. Des Moines Art Centre and State Historical Museum of Iowa are great ways to spend a day. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the top business-friendly motels in Des Moines?
Econo Lodge Urbandale-Northwest Des Moines caters to the needs of both corporate and leisure travellers. Around 13 kilometres west of downtown Des Moines, you'll have access to a swimming pool, WiFi and a range of business amenities.When the time comes to change from your business to casual attire and explore the sights, head directly to Adventureland. Blank Park Zoo is another top attraction worth seeing in Des Moines.
Are there any family-friendly hotels in Des Moines that are also business friendly?
If you're planning a family trip to Des Moines but still have to work, consider Home2 Suites by Hilton Des Moines at Drake University. This 3-stars escape features handy amenities like complimentary breakfast and laundry facilities. Baymont by Wyndham Des Moines Airport is another option that's ideal for both leisure and business travellers. It has a 2.5-stars rating and conveniences including a nearby theme park and a sauna. Once you've finished work, there are plenty of family-friendly attractions to explore around Des Moines. Adventureland and Blank Park Zoo guarantee fun for young and old.
Why book your business-friendly hotel in Des Moines with Expedia?
With conveniences like room service, conference rooms and on-site cafés, our business-friendly properties come with everything you'll need to close your big work deal — and then put your feet up! Enter your preferred travel dates and destination and Expedia will help you plan everything else.
How can I find cheap business-friendly hotels in Des Moines?
When work takes you to Des Moines, our "business friendly" filter will help you find a suitable hotel. From fast WiFi to workspaces and meeting rooms, they come with the amenities you need to do your job. Another handy tip? Narrow your search by your budget and preferred star rating to see the most affordable accommodation.
What is there to do in Des Moines near my business-friendly hotel?
You'll find loads of impressive things that'll fill up your itinerary in Des Moines. Check out renowned attractions like Adventureland, Blank Park Zoo and Living History Farms. Hoyt Sherman Place, Des Moines Art Centre and Science Centre of Iowa also lure many visitors.

Explore a world of travel with Expedia