Kid friendly Holidays in Southwest Houston 2026

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SpringHill Suites Houston Medical Center/NRG Park

1400 Old Spanish Trl Houston TX

20 min walk from MD Anderson Cancer Center

Stay at this business-friendly hotel in Houston. Enjoy free breakfast, free Wi-Fi and a fitness centre. Our guests praise the breakfast and the helpful staff ...

8.8/10 Excellent! (1,004 reviews)

"Nice stay and well"

Reviewed on 28 Sept 2026

Hyatt Place Houston/Galleria

5252 W. Alabama Houston TX

5 min drive from MD Anderson Cancer Center

Stay at this business-friendly hotel in Houston. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the breakfast and the helpful staff in ...

8.8/10 Excellent! (1,648 reviews)

"Clean room, Friendly staff, big rooms, perfect for families"

Reviewed on 29 Sept 2026

DoubleTree by Hilton Houston Medical Center Hotel & Suites

6800 Main Street Houston TX

2 min walk from MD Anderson Cancer Center

Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff in ...

See all 1,289 properties in Southwest Houston

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.