Luxury Holidays in Eastern Tennessee 2026

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Carnegie Hotel & Spa

1216 W State Of Franklin Rd Johnson City TN

2 hours drive from Great Smoky Mountains National Park

Stay at this spa hotel in Johnson City. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the restaurant and the helpful staff in their ...

9.8/10 Exceptional! (1,446 reviews)

"Nice hotel with some historic charm. The staff was friendly and nice. Overall a nice place to stay, but unless you have something to do at the ETSU campus, it is too close to all of the students, the traffic and noise for my personal preference. The bar is great! The restaurant is adequate, but they ..."

Reviewed on 23 Sept 2026

THE TENNESSEAN Hotel

531 Henley Street Knoxville TN

55 min drive from Great Smoky Mountains National Park

Stay at this luxury hotel in Knoxville. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...

9.4/10 Exceptional! (1,000 reviews)

"Room was super nice."

Reviewed on 21 Sept 2026

The Read House Hotel

107 West Martin Luther King Blvd Chattanooga TN

4 hours drive from Great Smoky Mountains National Park

Stay at this business-friendly hotel in Chattanooga. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean ...

9.6/10 Exceptional! (2,594 reviews)

"The room exceeded expectations. It was clean, beautiful view of downtown. I also appreciated the modern amenities such as usb charger ports for my electronics, the refrigerator and coffee bar setup in the room. The history of the hotel with the perfect location downtown makes it a perfect choice. ..."

Reviewed on 21 Sept 2026

See all 27,661 properties in Eastern Tennessee

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.