5 Star Hotels in Central United States, United States of America
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on Central United States 5 Star Hotels
Top Central United States 5 Star Hotels

Trump International Hotel & Tower Chicago
Trump International Hotel & Tower Chicago
9.4 out of 10, Exceptional, (1689)
The price is €465
includes taxes & fees
7 Sept - 8 Sept

Four Seasons Hotel Chicago
Four Seasons Hotel Chicago
9.4 out of 10, Exceptional, (1001)
The price is €534
includes taxes & fees
1 Sept - 2 Sept

The Langham, Chicago
The Langham, Chicago
9.8 out of 10, Exceptional, (1003)
The price is €548
includes taxes & fees
7 Sept - 8 Sept

1 Hotel Nashville
1 Hotel Nashville
9.2 out of 10, Wonderful, (826)
The price is €260
includes taxes & fees
2 Sept - 3 Sept

The Roosevelt New Orleans, A Waldorf Astoria Hotel
The Roosevelt New Orleans, A Waldorf Astoria Hotel
9.2 out of 10, Wonderful, (1002)
The price is €179
includes taxes & fees
28 Aug - 29 Aug

Hotel Crescent Court
Hotel Crescent Court
9.2 out of 10, Wonderful, (1003)
The price is €334
includes taxes & fees
31 Aug - 1 Sept

Conrad Nashville
Conrad Nashville
9.6 out of 10, Exceptional, (945)
The price is €257
includes taxes & fees
24 Aug - 25 Aug

The Peninsula Chicago
The Peninsula Chicago
9.8 out of 10, Exceptional, (1001)
The price is €630
includes taxes & fees
17 Aug - 18 Aug
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Central United States.

Palmer House a Hilton Hotel
17 E Monroe St, Chicago, IL
The price is €196 per night from 2 Sept to 3 Sept
€196
2 Sept - 3 Sept
includes taxes & fees
8.4/10 Very Good! (1,854 reviews)
Still don't see what you're looking for?
See all properties in Central United States.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Central United States
Enjoy access to sights and activities in the surrounding area during your stay in Central United States.

Top Central United States Hotel Reviews
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Near an Attraction
- Hotels near Wrigley Field
- Hotels near River Walk
- Hotels near Dollywood
- Hotels near Great Smoky Mountains National Park
- Hotels near Mall of America
- Hotels near Port of Galveston Cruise Terminal
- Hotels near Bourbon Street
- Hotels near Cedar Point
- Hotels near Lackland Air Force Base
- Hotels near Naval Base Great Lakes
- Hotels near Michigan Avenue
- Hotels near Navy Pier
- Hotels near Mount Rushmore
- Hotels near Canal Street
- Hotels near AT&T Stadium
- Hotels near Grand Ole Opry
- Hotels near Port of New Orleans
- Hotels near University of Texas at Austin
- Hotels near McCormick Place
- Hotels near Ark Encounter
Hotel Theme
- Adventure Sport Hotels in Central United States
- All Inclusive Hotels in Central United States
- Beach Hotels in Central United States
- Boutique Hotels in Central United States
- Business Hotels in Central United States
- Casino Hotels in Central United States
- Cheap Hotels in Central United States
- Family Friendly Hotels in Central United States
- Golf Hotels in Central United States
- Green / Sustainable Hotels in Central United States
- Historic Hotels in Central United States
- Hotels with Air Conditioning in Central United States
- Hotels with Bar in Central United States
- Hotels with Breakfast in Central United States
- Hotels with Childcare in Central United States
- Hotels with Connecting Rooms in Central United States
- Hotels with Parking in Central United States
- Hotels with Pool in Central United States
- Hotels with Restaurant in Central United States
- Hotels with Spa in Central United States
- Hotels with WiFi in Central United States
- Hotels with Yoga in Central United States
- LGBT-Friendly Hotels in Central United States
- Luxury Hotels in Central United States
- Pet Friendly Hotels in Central United States
- Romantic Hotels in Central United States
- Ski Hotels in Central United States
- Wedding Hotels in Central United States
More accommodation types in Central United States
- Condo Rentals in Central United States
- Holiday Homes in Central United States
- Cabin Rentals in Central United States
- Motels in Central United States
- Resorts in Central United States
- Aparthotels in Central United States
- Apartments in Central United States
- Cottages in Central United States
- Condo Resorts in Central United States
- Lodges in Central United States
- B&B in Central United States
- Guest Houses in Central United States
- Hostels in Central United States
- Villas in Central United States
- Caravan Parks in Central United States
- Castles in Central United States
- Inns in Central United States
More top Central United States Hotels
- Isla Grand Beach Resort
- Hollywood Casino & Hotel St. Louis
- Omni Austin Hotel
- The Westin Dallas Park Central
- Thousand Hills Resort Hotel
- Hotel Zaza Houston Museum District
- Best Western Downtown Plus Music Row
- Mt. Olympus Water & Theme Park Resort
- Omni Dallas Hotel
- Holiday Inn Resort South Padre Island - Beach Front by IHG
- DoubleTree by Hilton Hotel & Suites Houston by the Galleria
- citizenM Austin Downtown
- Hyatt Place Nashville Downtown
- Beachfront Palms Hotel Galveston
- Hyatt Regency St. Louis at The Arch
- Sand Rose Beach Resort
- Magnolia Hotel Dallas Downtown
- Riverwalk Plaza
- Grand Smokies Resort Lodge
- Drury Plaza Hotel San Antonio Riverwalk
Expedia's Latest Trends
Hotels
Flights
Cars
Packages
Holiday Rentals