5 Star Hotels in Key West, Florida

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Check availability on Key West 5 Star Hotels

Tonight
31 Dec - 1 Jan
Tomorrow
1 Jan - 2 Jan
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Key West.
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

3820 North Roosevelt Boulevard Key West FL
The price is €280 per night from 13 Jan to 14 Jan
€280
13 Jan - 14 Jan 2026
includes taxes & fees
8/10 Very Good! (1,803 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Key West

Stroll Duval Street's colourful shops and bars before catching the sunset celebration at Mallory Square with local performers. Explore Hemingway's historic home where six-toed cats roam freely, then snorkel the vibrant coral reefs just offshore.

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Frequently asked questions

What are the best 5-star hotels in Key West?
Step into a world of indulgence at Casa Marina Key West, Curio Collection by Hilton. This is one of the most highly rated 5-star hotels in Key West based on Expedia guest reviews. From its location to its amenities and services, you can expect the best of everything.
How much does it cost to stay in a 5-star hotel in Key West?
How much you pay for a 5-star hotel in Key West can vary according to when you want to travel and how long you plan to stay, among several factors. Take advantage of our price per night filter and other search tools to find the best rate on a high-end stay.

  • Search for the lowest price per night from €280

What makes a hotel 5 stars in Key West?
Impeccable guest service chatacterises every 5-star hotel in Key West. From the minute you step through the door, staff cater to your every need, whether recommending activities or providing a turn-down service. In addition, hotels must feature upscale conveniences to be considered for a 5-star rating. These can include luxury bathrooms, spa facilities, swimming pools, gastronomic restaurants and knowledgeable concierge.

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