Central San Diego Hotel Guide - Hotels with Spa in Central San Diego, San Diego
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Central San Diego Hotels with Spa
Tonight
8 Aug - 9 AugTomorrow
9 Aug - 10 AugNext weekend
14 Aug - 16 AugIn two weeks
21 Aug - 23 AugOur top choices for Central San Diego hotels with a spa
1. San Diego Mission Bay Resort
San Diego Mission Bay ResortMission Bay
- Unwind at this bay-view resort offering garden massages, poolside lounging, and a rejuvenating full-service spa retreat.
€254
includes taxes & fees
7 Sept - 8 Sept
2. Handlery Hotel
Handlery HotelMission Valley
- Surrender to spa treatments and poolside luxury at this hotel with massage rooms and a beautiful heated outdoor pool and hot tub.
€126
includes taxes & fees
23 Aug - 24 Aug
3. Legacy Resort Hotel & Spa
Legacy Resort Hotel & SpaMission Valley
- Indulge in a serene escape at this upscale hotel with a full-service spa, outdoor pool with free cabanas, and couples massage treatments.
€183
includes taxes & fees
30 Aug - 31 Aug
4. Best Western Plus Island Palms Hotel & Marina
Best Western Plus Island Palms Hotel & MarinaPoint Loma
- Blissful bay views and relaxing massages set the scene for a restorative escape at this waterfront sanctuary with bubbling hot tubs.
€139
includes taxes & fees
7 Sept - 8 Sept
5. Estancia La Jolla Hotel & Spa
Estancia La Jolla Hotel & SpaLa Jolla Farms
- Discover a tranquil garden retreat with luxurious spa treatments and a serene outdoor pool for the ultimate pampering getaway in La Jolla.
€348
includes taxes & fees
16 Aug - 17 Aug
6. Humphreys Half Moon Inn
Humphreys Half Moon InnPoint Loma
- Escape to this bayfront sanctuary with deep-tissue massages, a serene hot tub, and an outdoor pool for complete relaxation.
€205
includes taxes & fees
7 Sept - 8 Sept
7. Hyatt Regency Mission Bay Spa and Marina
Hyatt Regency Mission Bay Spa and MarinaMission Bay
- Experience coastal tranquility at this spa hotel with bay views, heated pools, and waterslides.
€242
includes taxes & fees
2 Sept - 3 Sept
8. Catamaran Resort and Spa
Catamaran Resort and SpaMission Beach
- Luxurious beachside retreat offers 10 spa treatment rooms, waterfront yoga, and a serene bay location for ultimate wellness.
€260
includes taxes & fees
7 Sept - 8 Sept
View all properties
Top Central San Diego Hotel Reviews
Embassy Suites by Hilton San Diego La Jolla
8/10 Good
"Everything was terrific, except, for one thing... this place changes you $26 PER NIGHT to use their parking garage! This should be free to use for guests, or at the very least, a small flat rate for the entire stay.alone. should park your car for you and pick you up out front, whenever you need, for that amount of money. This is nothing more than a pathetic cash grab and I doubt I will stay here again just based on this alone."
Best Western Seven Seas
10/10 Excellent
"The staff was very friendly, overnight staff was very helpful! I appreciate the security driving around. Clean room, cold AC, close to everything. Not walkable"
Crowne Plaza San Diego - Mission Valley by IHG
8/10 Good
"The hotel itself was very nice, a good place to stay. My only complaint is that we stayed there on a Saturday night and went to the restaurant for dinner. The "real restaurant" wasn't seating people (it looked closed) so we had to sit in an area of tables that felt like a small cafeteria. The food was mediocre and the ambiance was poor, and the food seemed to take a long time to arrive. The online reviews made it seem much nicer / appealing than it actually was. We wished that we had gone somewhere else."
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
8/10 Good
"Breakfast and affordability"
California Suites Hotel
10/10 Excellent
"Room was clean"
Town and Country San Diego
10/10 Excellent
"Staff was very helpful"
The Atwood Hotel San Diego - SeaWorld/Zoo
10/10 Excellent
"I spent a weekend at this property while visiting my daughter. Staff were nice, room was clean and organized. I had no issues at all during my stay and would stay there again."
The Alcala Hotel Mission Valley/Seaworld
10/10 Excellent
"Very good"
Hilton San Diego Mission Valley
10/10 Excellent
"Good"
Explore a world of travel with Expedia
- 3 Star Hotels in Pacific Beach
- 5 Star Hotels in La Jolla
- 5 Star Hotels in La Jolla Village
- Allied Gardens Hotels
- Bay Park Hotels
- Clairemont Hotels
- Crown Point Hotels
- Hotels near Crystal Pier
- Cheap Hotels in San Diego County
- Family Friendly Hotels in San Diego County
- Wedding Hotels in San Diego County
- Resorts in Fiesta Island
- Hilton Hotels in Fiesta Island
- Boutique Hotels in Gaslamp Quarter
- Hillcrest Hotels
- Hotels near Hotel Circle
- Kearny Mesa Hotels
- Cottages in La Jolla
- Luxury Hotels in La Jolla
- Motels in La Jolla
- Linda Vista Hotels
- Beach Hotels in Little Italy
- Motel 6 Hotels in Mira Mesa
- Hotels with Spa in Mira Mesa
- Mira Mesa Hotels
- Hotels with Restaurant in Miramar
- Miramar Hotels
- Hotels near Mission Beach
- Lgbt-Friendly Hotels in Mission Beach
- Hotels near Mission Valley Mall
- Casino Hotels in Mission Valley
- Cheap Hotels in Mission Valley
- Mission Valley Hotels
- Beach Hotels in North Park
- Holiday Homes in Old Town Transit Center
- Beach Hotels in Pacific Beach
- Boutique Hotels in Pacific Beach
- Cheap Hotels in Pacific Beach
- Family Friendly Hotels in Pacific Beach
- Hotels with Restaurant in Pacific Beach
- Luxury Hotels in Pacific Beach
- Pet Friendly Hotels in Pacific Beach
- All Inclusive Hotels in San Diego
- Business Hotels in San Diego
- Green / Sustainable Hotels in San Diego
- Hotels with Bar in San Diego
- Hotels with Breakfast in San Diego
- Hotels with Childcare in San Diego
- Hotels with Connecting Rooms in San Diego
- Romantic Hotels in San Diego
- Hotels with Spa in San Diego
- Cheap Hotels in Sorrento Valley
- Sorrento Valley Hotels
- Hotels near Stadium Golf Center & Batting Cages
- Beach Hotels in Torrey Pines
- Torrey Pines Hotels
- Flights from Montgomery Field
- Flights from Auckland (AKL) to San Diego (MYF)
- Flights from Amman (AMM) to San Diego (MYF)
- Flights from Atlanta (ATL) to San Diego (MYF)
- Flights from Chico (CIC) to San Diego (MYF)
- Flights from Concord (CON) to San Diego (MYF)
- Flights from Fort Lauderdale (FLL) to San Diego (MYF)
- Flights from New York (JFK) to San Diego (MYF)
- Flights from Lake Charles (LCH) to San Diego (MYF)
- Flights from Manta (MEC) to San Diego (MYF)
- Flights from Modesto (MOD) to San Diego (MYF)
- Flights from Mesa (MSC) to San Diego (MYF)
- Flights from Oceanside (OCN) to San Diego (MYF)
- Flights from Pago Pago (PPG) to San Diego (MYF)
- Flights from Richland (RLD) to San Diego (MYF)
- Flights from San Francisco (SFO) to San Diego (MYF)
- Flights from Santa Monica (SMO) to San Diego (MYF)
- Flights from Orange County (SNA) to San Diego (MYF)
- Flights from Santa Ynez (SQA) to San Diego (MYF)
- Flights from Thermal (TRM) to San Diego (MYF)
- Birch Aquarium
- Fleet Science Center
- Hotel Circle
- Visit La Jolla Farms
- Visit La Jolla Village
- La Jolla Shores Park
- Marine Corps Air Station Miramar
- Mission Bay
- Visit North Mission Beach
- Pacific Beach Park
- Pechanga Arena
- Visit Hillcrest
- Visit Linda Vista
- Visit Miramar
- Visit Pacific Beach
- Scripps Ranch Holidays
- Torrey Pines Golf Course