Barrio de Santiago

Mérida

A historic stone gate with intricate carvings and two towers.
A gallery with six framed artworks on the walls and a chandelier hanging from the ceiling.
A street scene with a colorful cart, parked cars, and buildings.
A street with a restaurant, outdoor seating, and parked cars.
A staircase with ornate railings, a star-shaped light fixture, and a chessboard in the background.

Stay near popular Barrio de Santiago attractions

Casa Frederick Catherwood

9.0/10 (4 reviews)
Study a collection of 19th-century images of jungle-covered ancient ruins, which provided historians with a wealth of knowledge about the Mayans.
See properties

Things to do

Mérida: Panoramic Sightseeing Tour Bus Ticket with 2 Routes

Mérida México: Panoramic Sightseeing City Tour with 2 Routes

€9
per adult
80% of travellers recommend
Mérida México: Panoramic Sightseeing City Tour with 2 Routes
Mérida: La Quinta Montes Molina Museum Entrance

Mérida: La Quinta Montes Molina Museum Entrance

€8
per adult
Mérida: La Quinta Montes Molina Museum Entrance
Las Coloradas, Río Lagartos and Playa Cancunito Tour from Mérida

Las Coloradas, Río Lagartos and Playa Cancunito Tour from Mérida

€100
per adult
88% of travellers recommend
Las Coloradas, Río Lagartos and Playa Cancunito Tour from Mérida
Isla Columpios & Progreso Day Trip

Isla Columpios, Corchito & Progreso Day Tour

€69
per adult
90% of travellers recommend
Isla Columpios, Corchito & Progreso Day Tour
From Mérida: Explore 4 Rural Cenotes & Enjoy a Traditional Lunch

From Mérida: Explore 4 Rural Cenotes & Enjoy a Traditional Lunch

€70
per adult
From Mérida: Explore 4 Rural Cenotes & Enjoy a Traditional Lunch
Brewery Tour and Beer Tasting | Tour y Degustación de Cerveza

Brewery Tour and Beer Tasting | Tour y Degustación de Cerveza

€35
per adult
Brewery Tour and Beer Tasting | Tour y Degustación de Cerveza
See all activities in Mérida

Top hotels in Barrio de Santiago

Hotel Unknown

Hotel Unknown

3.5 out of 5
559 Calle 53 Mérida YUC
The price is €73 per night from 6 Sept to 7 Sept
€73
6 Sept - 7 Sept
includes taxes & fees
Stay at this spa hotel in Mérida. Enjoy free breakfast, free Wi-Fi and a full-service spa. Our guests praise the helpful staff in their reviews. Popular attractions ...
Hotel Unknown
Hotel Casa 57

Hotel Casa 57

3 out of 5
539 C. 57 Centro Mérida Yuc.
The price is €50 per night from 1 Sept to 2 Sept
€50
1 Sept - 2 Sept
includes taxes & fees
Stay at this hotel in Mérida. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Our guests praise the helpful staff in their reviews. Popular ...
Hotel Casa 57
Casa Aura Hotel, Mérida

Casa Aura Hotel, Mérida

3.5 out of 5
Calle 57, 543-A, entre 66 y 68 Mérida YUC
The price is €43 per night from 16 Aug to 17 Aug
€43
16 Aug - 17 Aug
includes taxes & fees
Stay at this boutique hotel in Mérida. Enjoy free breakfast, free Wi-Fi and a 24-hour front desk. Our guests praise the helpful staff in their reviews. Popular ...
Casa Aura Hotel, Mérida
Casa Loreto 1893

Casa Loreto 1893

5 out of 5
619 Calle 59 Mérida
The price is €183 per night from 5 Sept to 6 Sept
€183
5 Sept - 6 Sept
includes taxes & fees
Stay at this luxury hotel in Mérida. Enjoy free Wi-Fi, free parking and room service. Popular attractions Paseo de Montejo and Plaza Grande are located ...
9.8/10 Exceptional! (164 reviews)
"Amazing boutique hotel. Clean, quiet and close to the main downtown area. A grocery store and laundromat near by. Staff ready to help with reservations and recommendations."

Reviewed on 30 Jul 2026

Casa Loreto 1893
Hotel Ambassador Merida

Hotel Ambassador Merida

3 out of 5
Calle 59 No.546 X 68 Mérida YUC
The price is €38 per night from 16 Aug to 17 Aug
€38
16 Aug - 17 Aug
includes taxes & fees
Stay at this hotel in Mérida. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their reviews. Popular attractions ...
Hotel Ambassador Merida
Hotel Boutique La Casona By Kavia

Hotel Boutique La Casona By Kavia

3.5 out of 5
532 Calle 59 Centro Mérida YUC
The price is €47 per night from 8 Aug to 9 Aug
€47
8 Aug - 9 Aug
includes taxes & fees
Stay at this hotel in Mérida. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff in their reviews. Popular attractions ...
8.6/10 Excellent! (346 reviews)
"The property is a bit outdated butentails a beautiful garden in the lower level and a very small pool. The Property is well kept the staff was friendly and accommodating. I paid for breakfast to be included and there wasn’t much a variety, but it was still good. The hotel is located by the center ..."

Reviewed on 24 Jul 2026

Hotel Boutique La Casona By Kavia
See all 1,390 properties in Barrio de Santiago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Barrio de Santiago

Find the best Barrio de Santiago areas for the activities you enjoy most.
A historic building with a clock tower, a street with light trails from moving vehicles, and a red building with a sign.

Mérida Centro

Mérida Centro is known for its abundant dining options, and you can plan a trip to Paseo de Montejo and Plaza Grande while you're in town.

A sunset over a body of water with a rocky shoreline.
Photo by Tony Lozano
Open Photo by Tony Lozano

Chelem

If you're spending some time in Chelem, Chelem Park is a top sight worth visiting.

A row of boats on a beach with a sunset in the background.
Photo by Alex Vizcaino
Open Photo by Alex Vizcaino

Chicxulub Puerto

Travellers like the beaches in Chicxulub Puerto, and Playa Uaymitun is a top attraction you might want to visit.

A historic building with ornate architecture, palm trees, and well-maintained landscaping.
Photo by Tony Lozano
Open Photo by Tony Lozano

Zona Paseo Montejo

While visiting Zona Paseo Montejo, you might make a stop by sights like Paseo de Montejo and Paseo 60.

A beach with wooden posts and a sunset sky.

Chuburna Puerto

You might consider checking out Chelem Park while you're exploring Chuburna Puerto and the larger Progreso area.

Barrio de Santiago

Choose two or more items and save on your trip: