Santa Ana
Panama City
Popular places to visit
Multiplaza Pacific Mall
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Avenida Balboa
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.
Amador Causeway
You can learn about the history of Ancon with a visit to Amador Causeway. Stroll along the seaside or visit the shops in this vibrant area.
Cinta Costera
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.
Calle 50
You can find out about the history of Panama City when you stop by Calle 50. Discover the area's casinos or seek out its local tours.
Uruguay Street
During your visit to Panama City, you can search for that perfect souvenir at Uruguay Street. While in this family-friendly area, you can savour the top-notch restaurants.
Things to do
Panama City Visit an Indian town Embera and waterfall with lunch
Panama City: POIN Swing Experience
All-inclusive 8-hour catamaran tour to Isla Taboga from Panama City
Panama City: Poin Glass Observation Deck Ticket with VR Tour
From Panama City: San Blas Island Hopping Day Tour
Top hotels in Santa Ana
Casco View Apartments
Quite disappointing. The most obvious reason for the poor review is the immediate area the property is in. I read negative reviews about this but didn’t quite get the full scope of what the neighbouring properties were like until we actually stayed there. When a property is in such a rough area, ...
Reviewed on 24 Mar 2026
Hotel Riu Plaza Panama
The hotel stay was good overall, the breakfast was excellent but I had one complaint. There was no coffee machine in the room, and when I reported it to the front desk, it was not addressed.
Reviewed on 24 Mar 2026
Crowne Plaza Panama Airport by IHG
Clean room / staff / airport shuttle / outdoor pool
Reviewed on 24 Mar 2026
Sheraton Grand Panama
Breakfast was great , clean room and staff was nice
Reviewed on 20 Mar 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Nice place for an older hotel. Had fun seeing a pro boxing fight walking distance from Hotel
Reviewed on 24 Mar 2026
W Panama
Great location and friendly staff. Housekeeping could have been better.
Reviewed on 24 Mar 2026
Other neighbourhoods around Santa Ana
Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
San Felipe
While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.
El Chorrillo
While El Chorrillo isn't home to many top sights, Albrook Shopping Mall and Maracana Stadium are some notable places to visit nearby.
Calidonia
Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Cinta Costera.
Balboa
The restaurants and shopping are just a few features travellers like about Balboa. If you want to do some sightseeing nearby, Albrook Shopping Mall and Flag of Cerro Ancón are a few top places to visit.
Curundu
While Curundu isn't home to many top sights, Albrook Shopping Mall and Iglesia del Carmen are some notable places to visit nearby.
