Santa Ana
Panama City
Visit Santa Ana
Stay near popular Santa Ana attractions
Things to do
Panama Canal: The Most Complete Wildlife Experience
€41
per adult
98% of travellers recommend
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
€85
per adult
94% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
€28
per adult
100% of travellers recommend
From Panama City: San Blas Island Hopping Day Tour
€125
per adult
98% of travellers recommend
Half day of Panama city and canal tour: shared and private
€57
per adult
96% of travellers recommend
Panama: Monkey and Sloth Jungle Habitat Panama Tour
€52
per adult
100% of travellers recommend
Top hotels in Santa Ana
Hotel Caracas - Casco Viejo
Plaza De Santa Ana Panama City Provincia di Panama
The price is €39 per night from 14 Oct to 15 Oct
€39
14 Oct - 15 Oct
includes taxes & fees
Stay at this hotel in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Cinta Costera ...
8/10 Very good! (19 reviews)
"Good location but basic otherwise. Staff not overly helpful on the whole."
Reviewed on 27 Sept 2026
Casco View Life Residences
C. 16 Oeste Panama City Provincia de Panamá
The price is €103 per night from 2 Oct to 3 Oct
€103
2 Oct - 3 Oct
includes taxes & fees
Stay at this business-friendly condo in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall ...
9/10 Wonderful! (106 reviews)
"We really enjoyed our stay at Casco View. It was an easy walk into Casca Viejo and centrally located. The host uses a guesty app to provide room details, apartment codes, etc, so it was a really easy and smooth process to get checked in. The room itself was very clean and well appointed. We stayed ..."
Reviewed on 8 Sept 2026
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
The price is €134 per night from 25 Oct to 26 Oct
€134
25 Oct - 26 Oct
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (5,988 reviews)
"Great hotel. The breakfast could have been better but its centrally located with other food options close by."
Reviewed on 1 Oct 2026
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
The price is €136 per night from 30 Oct to 31 Oct
€136
30 Oct - 31 Oct
includes taxes & fees
Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...
Central Hotel Panama Casco Viejo
Plaza de la Independencia Casco Viejo Panama City Panama
The price is €185 per night from 5 Oct to 6 Oct
€185
5 Oct - 6 Oct
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, a full-service spa and 3 restaurants. Our guests praise the helpful staff and the clean rooms in their ...
9/10 Wonderful! (1,002 reviews)
"This is a great hotel, and the location was perfect. The rooms were nice, and the staff were very friendly. I would highly recommend it."
Reviewed on 1 Oct 2026
Megapolis Hotel Panamá
Avenida Balboa Panama City
The price is €140 per night from 26 Oct to 27 Oct
€140
26 Oct - 27 Oct
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.6/10 Excellent! (1,768 reviews)
"Where can I start?! First of all the hotel is connected to the mall by a crosswalk!!! The food, drinks, aesthetics, staff, location, all amazing I’m definitely booking the same hotel when I return. Uber was $5 max to local spots. Shout out to the breakfast buffett staff. Best I’ve ever had. The fresh ..."
Reviewed on 1 Oct 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Santa Ana
Find the best Santa Ana areas for the activities you enjoy most.
Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by Journey Of A Nomadic Family
Open Photo by Journey Of A Nomadic Family
Bella Vista
Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.
El Cangrejo
The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
San Francisco
San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.
San Felipe
While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.
