San Antonio Hotel Guide. Hotels in Uptown, San Antonio, United States of America
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Uptown
Check prices for these dates
Our top choices for Uptown hotels
8.6 out of 10, Excellent, (1000)
"Great hotel"
Kassie
The price is €112
includes taxes & fees
3 Jan - 4 Jan 2026
Courtyard by Marriott San Antonio Airport/North Star Mall
Courtyard by Marriott San Antonio Airport/North Star MallUptown
8.2 out of 10, Very good, (788)
"good place to stay"
nadine
The price is €79
includes taxes & fees
4 Jan - 5 Jan 2026
Estancia del Norte San Antonio, Tapestry Collection by Hilton
Estancia del Norte San Antonio, Tapestry Collection by HiltonUptown
8.8 out of 10, Excellent, (1001)
"The staff was friendly, the room was spacious yet cosy and the bed was so comfortable "
Lauren
The price is €136
includes taxes & fees
18 Dec - 19 Dec
SpringHill Suites by Marriott San Antonio Airport
SpringHill Suites by Marriott San Antonio AirportUptown
7.8 out of 10, Good, (1001)
"Close to airport and free shuttle. Great place "
Lorena
The price is €95
includes taxes & fees
21 Dec - 22 Dec
TownePlace Suites by Marriott San Antonio Airport
TownePlace Suites by Marriott San Antonio AirportUptown
8.8 out of 10, Excellent, (1002)
"Convenient to airport and a good value."
Cynthia
The price is €108
includes taxes & fees
20 Dec - 21 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Uptown
Find the best Uptown areas for the activities you enjoy most.
Downtown San Antonio
Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.
Far West Side
While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.
Medical Center District
While visiting Medical Center District, you might make a stop by sights like USAA Corporate Office Headquarters and The San Antonio Art Institute.
Stone Oak
Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.
Northwest Side
If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.
Explore a world of travel with Expedia
Frequently asked questions
Hotels near other Attractions
Destinations near San Antonio
More top Uptown Hotels
- Hyatt Vacation Club at Wild Oak Ranch, San Antonio
- Drury Plaza Hotel San Antonio Riverwalk
- Menger Hotel
- La Quinta Inn & Suites by Wyndham San Antonio Downtown
- Hotel Contessa
- Hyatt Regency San Antonio Riverwalk
- Omni La Mansion del Rio
- Sonesta ES Suites San Antonio Downtown Alamo Plaza
- La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
- La Quinta Inn & Suites by Wyndham San Antonio Riverwalk
- AC Hotel by Marriott San Antonio Riverwalk
- Crockett Hotel