South San Diego Apart Hotels

A beach with a pier extending into the ocean, a person standing on the shore, and the sun setting over the water.

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Our top choices for South San Diego aparthotels

A spacious lounge area with a sofa, a coffee table, and a bar with stools.

1. Marriott Vacation Club®, San Diego

Downtown San Diego

Veronica Dangerfield

includes taxes & fees

16 Nov - 17 Nov

A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

2. City24 Hotel Little Italy Mission Hills

Middletown

Donavin

includes taxes & fees

4 Nov - 5 Nov

A spacious lobby with a sofa, chairs, a bookshelf, and a large window with a view of greenery.

3. Uptown Inn by Vantaggio - Limited Service Apart-Hotel

Hillcrest

Aviana

includes taxes & fees

8 Nov - 9 Nov

4. Little Italy Inn - Limited Service Apart Hotel

Downtown San Diego

Olivia

includes taxes & fees

3 Nov - 4 Nov

A neatly made bed with white and gold bedding, two bedside tables with lamps, and three wall-mounted mirrors.

5. Kasa Gaslamp Quarter San Diego

Downtown San Diego

Eric

includes taxes & fees

8 Nov - 9 Nov

A dining table set with white bowls, wine glasses, and a vase with flowers.

6. The Penn Hotel - Smart TV, AC & Walk to Gaslamp!!!

Downtown San Diego

includes taxes & fees

3 Nov - 4 Nov

🛋️ Seamless flow between living, dining, and sleeping areas — ideal for entertaining or staying connected during an extended stay.

7. The Penn Hotel - Queen Bed, AC & Walk to Gaslamp!!

Downtown San Diego

includes taxes & fees

8 Nov - 9 Nov

A rooftop pool with lounge chairs and a city skyline in the background.

8. Kasa Little Italy San Diego

Downtown San Diego

Nirmeen

includes taxes & fees

16 Nov - 17 Nov

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Top South San Diego Hotel Reviews

The Dana on Mission Bay

8/10 Good

"The firefly restaurant is worth the visit. The Dana was located in the heart of where we wanted to be. One surprise was the room, not what we had envisioned as a 4 star hotel. There wasn't a door from the main room to the sink. The toilet shower area was quite small as well. It did have ready hot water at all times which were greatly appreciated. Lacking in appeal it was still a good place to stay."

Bay Club Hotel & Marina

10/10 Excellent

"Great view of the marina. Parking was an issue as I have a large truck and the underground parking was tough to fit into, but we made do. Staff was great. Across the street is a small boat launch and it was fun to go over at night and see the large birds and the seals try to convince fisherman to offer up some bait. Pillows were small and way too giving. Shower had fantastic water pressure. Will stay here again."

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