Photo by Southernmost Illinois Tourism Bureau

Search Guest Houses in Southern Illinois

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
5 Dec - 7 Dec
In two weeks
12 Dec - 14 Dec
In one month
26 Dec - 28 Dec
In two months
23 Jan - 25 Jan

Featured Guest Houses in Southern Illinois and around

Exterior
Riverview Mansion Hotel

Riverview Mansion Hotel

3.0 star property
Golconda
8.6 out of 10, Excellent, (26)
"Historic also needs to be cleaned"
United States
jolanta
Riverview Mansion Hotel
Outdoor dining
Modern 2BR Lake Suite • Dock & Firepit

Modern 2BR Lake Suite • Dock & Firepit

Marion
10.0 out of 10, Exceptional, (16)
"This was a cozy and convenient place to stay for our Garden of the Gods day trip."
United States
Joshua R.
The price is €238
includes taxes & fees
30 Nov - 1 Dec
Modern 2BR Lake Suite • Dock & Firepit
Fridge, microwave, coffee/tea maker, cookware/dishes/utensils
Cozy, Fun, and One-Of-A-Kind!

Cozy, Fun, and One-Of-A-Kind!

Shaw
9.4 out of 10, Exceptional, (117)
"Cute place - exactly what we needed for this trip to St. Louis. "
United States
Angela L.
The price is €127
includes taxes & fees
30 Nov - 1 Dec
Cozy, Fun, and One-Of-A-Kind!
Front of property
Grand Center Inn

Grand Center Inn

3.0 star property
Grand Center
9.4 out of 10, Exceptional, (67)
"Great place"
United States
Nguyet
The price is €183
includes taxes & fees
4 Dec - 5 Dec
Grand Center Inn
TV, video games
In the center of all Historic Main Street has to offer

In the center of all Historic Main Street has to offer

Grafton
7.0 out of 10, Good, (2)
"Such a great location! Very clean & cute house!"
United States
Janelle C.
The price is €553
includes taxes & fees
29 Nov - 30 Nov
In the center of all Historic Main Street has to offer
Interior
Charming Home with Country Views

Charming Home with Country Views

Grafton
10.0 out of 10, Exceptional, (39)
"Friends weekend trip. Great location, as advertised, smooth check in/out process. "
United States
deb r.
The price is €277
includes taxes & fees
26 Nov - 27 Nov
Charming Home with Country Views
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Southern Illinois Hotel Reviews

Best Western Delta Inn

Best Western Delta Inn

10/10 Excellent
"Nice room"
Daniel 1-night trip
Posted 3 days ago
Best Western Delta Inn

Find out more about Southern Illinois

Southern Illinois Guest Houses information

Number of reviews
261
Accommodation
4 Guest Houses
Lowest Price
€127
Highest Price
€558

Explore a world of travel with Expedia