Southern Illinois Guest Houses

A forested valley with autumn foliage, a rocky cliff, and a sunset.

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Our top choices for Southern Illinois guest houses

A cozy living room with a large Christmas tree, a fireplace, and a dining area with a table and chairs.

1. Riverview Mansion Hotel

Golconda

Jessica

includes taxes & fees

23 Oct - 24 Oct

A lakeside cabin with outdoor seating and string lights.

2. Lakefront Suite · Dock, No-Wake Cove & Firepit

Marion

Sam M.

A brick house with a covered porch, a stone pathway, and a garden bed.

3. Hidden in a Private Wooded Area

Carbondale

Alla H.

includes taxes & fees

12 Nov - 13 Nov

A modern living room with a brick wall, a sofa, a coffee table, and a TV.

4. Cozy, Fun, and One-Of-A-Kind!

Shaw

Riley C.

includes taxes & fees

14 Oct - 15 Oct

A multi-story building with a grand entrance, large windows, and a well-lit facade at night.

5. Grand Center Inn

Grand Center

Leon and Janis

includes taxes & fees

25 Oct - 26 Oct

A single-story house with a front porch, two chairs, and a small garden area.

6. Charming Home with Country Views

Grafton

Scarlett L.

A modern kitchen with stainless steel appliances, a large window, and a green cabinet.

7. The Mediterranean House 1858

Perryville

includes taxes & fees

14 Oct - 15 Oct

A spacious living room with wooden beams, a television, a sofa, and a coffee table.

8. In the center of all Historic Main Street has to offer

Grafton

Janelle C.

includes taxes & fees

27 Oct - 28 Oct

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Top Southern Illinois Hotel Reviews

Drury Inn & Suites Marion

8/10 Good

"The room was nice and clean, a bit on the small side but overall it was nice. The pool in the hot tub definitely was a plus for the kids, and I would say it was nice that they served dinner as well, but unfortunately my kids did not enjoy it. The breakfast was OK"

Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent

"The staff was very friendly, but I loved that they dress professionally, hair is neat, and they take pride in their work. Meals were wonderfully , staff paid attention to all the details and ensured that everything stayed fresh, full, and areas maintained."

Comfort Inn Edwardsville - St. Louis

8/10 Good

"This hotel is always a convenient choice and is well run. Staff are always helpful. I always love that I see the STL arch from the parking lot! I do hope the property is scheduled for some carpeting upgrades soon. The elevator was is need of a refresh and I was surprised to see a rip in the carpet of my otherwise suitable room."

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