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Southern Illinois Hotels
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Top 10 trending Southern Illinois hotels

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon
9.6 out of 10, Exceptional, (1413)
The price is €91
includes taxes & fees
31 Aug - 1 Sept

SureStay Hotel by Best Western Whittington Rend Lake
SureStay Hotel by Best Western Whittington Rend Lake
8.8 out of 10, Excellent, (843)
The price is €77
includes taxes & fees
31 Aug - 1 Sept

The Principal Hotel
The Principal Hotel
9.8 out of 10, Exceptional, (116)
The price is €108
includes taxes & fees
12 Aug - 13 Aug

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
9.4 out of 10, Exceptional, (461)
The price is €99
includes taxes & fees
17 Aug - 18 Aug

Harrah's Metropolis Hotel & Casino
Harrah's Metropolis Hotel & Casino
8.4 out of 10, Very good, (1004)
The price is €102
includes taxes & fees
17 Aug - 18 Aug

Hilton Garden Inn Mattoon, Il
Hilton Garden Inn Mattoon, Il
8.8 out of 10, Excellent, (173)
The price is €129
includes taxes & fees
24 Aug - 25 Aug
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Showing deals for:22 Aug - 24 Aug
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The Shelby Inn
Shelbyville
8.8/10Excellent (116 reviews)
10% off
Price is €252
€126 per night
includes taxes & fees
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Near an Attraction
Southern Illinois University

Southern Illinois University
Enjoy the student vibe when you visit Southern Illinois University during your trip to Carbondale. Visit the shops and top-notch restaurants in this family-friendly area.
Harrah's Metropolis
Harrah's Metropolis
Why not roll the dice with a visit to Harrah's Metropolis during your visit to Metropolis? Visit the casinos and top-notch restaurants in this family-friendly area.
Learn more about Southern Illinois
Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau
Top Southern Illinois Hotel Reviews

Drury Inn & Suites St. Louis O'Fallon, IL
10/10 Excellent
More cheap stays in Southern Illinois
More cheap stays in Southern Illinois

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr, O'Fallon, IL
The price is €50 per night from 24 Aug to 25 Aug
€50
24 Aug - 25 Aug
includes taxes & fees
7.4/10 Good! (1,009 reviews)

4 Star Hotels
4 properties
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Areas of Southern Illinois
Hotel Theme
- Adventure Sport Hotels in Southern Illinois
- Beach Hotels in Southern Illinois
- Business Hotels in Southern Illinois
- Casino Hotels in Southern Illinois
- Cheap Hotels in Southern Illinois
- Family Friendly Hotels in Southern Illinois
- Golf Hotels in Southern Illinois
- Green / Sustainable Hotels in Southern Illinois
- Historic Hotels in Southern Illinois
- Hotels with Air Conditioning in Southern Illinois
- Hotels with Bar in Southern Illinois
- Hotels with Breakfast in Southern Illinois
- Hotels with Connecting Rooms in Southern Illinois
- Hotels with Parking in Southern Illinois
- Hotels with Pool in Southern Illinois
- Hotels with Restaurant in Southern Illinois
- Hotels with Spa in Southern Illinois
- Hotels with WiFi in Southern Illinois
- Luxury Hotels in Southern Illinois
- Pet Friendly Hotels in Southern Illinois
- Romantic Hotels in Southern Illinois
- Ski Hotels in Southern Illinois
- Wedding Hotels in Southern Illinois
More accommodation types in Southern Illinois
- Holiday Homes in Southern Illinois
- Cabin Rentals in Southern Illinois
- Apartments in Southern Illinois
- Motels in Southern Illinois
- Cottages in Southern Illinois
- Caravan Parks in Southern Illinois
- Aparthotels in Southern Illinois
- Farmstay in Southern Illinois
- Condo Rentals in Southern Illinois
- B&B in Southern Illinois
- Lodges in Southern Illinois
- Guest Houses in Southern Illinois
- Villas in Southern Illinois
- Chalets in Southern Illinois
- Resorts in Southern Illinois
Hotels Near Southern Illinois, Illinois
- St. Charles Hotels
- Evansville Hotels
- Paducah Hotels
- Maryland Heights Hotels
- Chesterfield Hotels
- Terre Haute Hotels
- Cape Girardeau Hotels
- O'Fallon Hotels
- Effingham Hotels
- Marion Hotels
- Carbondale Hotels
- Mount Vernon Hotels
- Decatur Hotels
- Hazelwood Hotels
- Fairview Heights Hotels
- Fenton Hotels
- Grafton Hotels
- Gilbertsville Hotels
- Collinsville Hotels
- Alton Hotels
More top Southern Illinois Hotels
- Comfort Suites Mount Vernon
- Best Western Troy Hotel
- Radisson Hotel Fairview Heights - St. Louis
- Drury Inn & Suites Marion
- Super 8 by Wyndham Marion
- DoubleTree by Hilton Mt. Vernon
- Baymont by Wyndham O'Fallon St. Louis Area
- La Quinta Inn & Suites by Wyndham Effingham
- Hilton Garden Inn St. Louis Shiloh/O'Fallon IL
- Country Inn & Suites by Radisson, Fairview Heights, IL
- Baymont by Wyndham Effingham
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