Photo by Southernmost Illinois Tourism Bureau

Southern Illinois Hotels

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Property class

Top 10 trending Southern Illinois hotels

Days Inn by Wyndham Mount Vernon

2.0 star property
6.6 out of 10, (1003)
"The pool was clean & warm the rooms we’re spacious & the location is perfect."
The price is €71
includes taxes & fees
5 Aug - 6 Aug
Days Inn by Wyndham Mount Vernon

Drury Plaza Hotel Mt. Vernon

3.0 star property
9.6 out of 10, Exceptional, (1400)
"Very nice staff and great place to stay"
The price is €92
includes taxes & fees
10 Aug - 11 Aug
Drury Plaza Hotel Mt. Vernon

Baymont by Wyndham Marion

2.5 star property
8.4 out of 10, Very good, (1036)
"Just stayed 1 night Very good 👍 "
The price is €93
includes taxes & fees
1 Sept - 2 Sept
Baymont by Wyndham Marion

La Quinta Inn & Suites by Wyndham Effingham

3.0 star property
9.2 out of 10, Wonderful, (1007)
"Love this place staff is great and rooms are clean."
The price is €98
includes taxes & fees
3 Aug - 4 Aug
La Quinta Inn & Suites by Wyndham Effingham

Super 8 by Wyndham Carbondale

2.0 star property
7.2 out of 10, Good, (1002)
"This motel is clean and quiet, with fast check in."
The price is €65
includes taxes & fees
4 Aug - 5 Aug
Super 8 by Wyndham Carbondale

Drury Inn & Suites Marion

3.0 star property
9.4 out of 10, Exceptional, (1003)
"This hotel was excellent! Clean and friendly staff "
The price is €96
includes taxes & fees
1 Sept - 2 Sept
Drury Inn & Suites Marion

Quality Inn Effingham North

2.5 star property
8.4 out of 10, Very good, (898)
"Great hotel. Will stay again. "
The price is €80
includes taxes & fees
10 Aug - 11 Aug
Quality Inn Effingham North

SureStay Hotel by Best Western Whittington Rend Lake

2.5 star property
8.8 out of 10, Excellent, (837)
"Very good place to stay"
The price is €72
includes taxes & fees
3 Aug - 4 Aug
SureStay Hotel by Best Western Whittington Rend Lake

Super 8 by Wyndham Mt. Vernon IL

2.5 star property
7.8 out of 10, Good, (1001)
"We had a good stay, room was clean and comfortable. Would stay again."
The price is €61
includes taxes & fees
10 Aug - 11 Aug
Super 8 by Wyndham Mt. Vernon IL

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 star property
9.4 out of 10, Exceptional, (457)
"Excellent stay!"
The price is €100
includes taxes & fees
17 Aug - 18 Aug
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Days Inn & Suites by Wyndham Casey

2.0 star property
7.4 out of 10, Good, (755)
"Great location and a quite place to stay and relax "
The price is €69
includes taxes & fees
1 Sept - 2 Sept
Days Inn & Suites by Wyndham Casey

Comfort Suites Mount Vernon

2.5 star property
8.8 out of 10, Excellent, (1004)
"We stayed here as a stop for the night and were quite pleased with this motel."
The price is €123
includes taxes & fees
24 Aug - 25 Aug
Comfort Suites Mount Vernon

Red Lion Inn & Suites Pontoon Beach

2.5 star property
8.0 out of 10, Very good, (469)
"Had a great stay here. Room was nice and staff were very friendly. Lots of places to eat within a 15 minute drive and breakfast was very good."
The price is €59
includes taxes & fees
5 Aug - 6 Aug
Red Lion Inn & Suites Pontoon Beach

Harrah's Metropolis Hotel & Casino

3.5 star property
8.2 out of 10, Very good, (1001)
"Great stay"
The price is €118
includes taxes & fees
3 Aug - 4 Aug
Harrah's Metropolis Hotel & Casino

Seasons Inn & Suites Highland

2.5 star property
8.2 out of 10, Very good, (594)
"Friendly staff, spacious rooms, had a positive experience. "
Seasons Inn & Suites Highland

La Quinta Inn & Suites by Wyndham Pontoon Beach

3.0 star property
7.8 out of 10, Good, (477)
"Nice, clean hotel in a safe area. 5 night stay was very comfortable."
The price is €79
includes taxes & fees
17 Aug - 18 Aug
La Quinta Inn & Suites by Wyndham Pontoon Beach

Days Inn by Wyndham Effingham

2.0 star property
6.0 out of 10, (1001)
"Room very spacious and clean"
The price is €53
includes taxes & fees
5 Aug - 6 Aug
Days Inn by Wyndham Effingham

Super 8 by Wyndham Collinsville St. Louis

2.0 star property
7.0 out of 10, Good, (1002)
"Great stay"
The price is €68
includes taxes & fees
22 Aug - 23 Aug
Super 8 by Wyndham Collinsville St. Louis

Best Western Plus Pontoon Beach

3.0 star property
8.6 out of 10, Excellent, (717)
"Nice rooms, pool and breakfast. Would definitely stay again."
The price is €86
includes taxes & fees
5 Aug - 6 Aug
Best Western Plus Pontoon Beach

The Principal Hotel

3.5 star property
9.8 out of 10, Exceptional, (107)
"Perfect stay! "
The price is €108
includes taxes & fees
3 Aug - 4 Aug
The Principal Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Showing deals for:15 Aug - 17 Aug
Save an average of 15% on thousands of hotels when you're signed in

Near an Attraction

Southern Illinois University
Southern Illinois University

Southern Illinois University

Enjoy the student vibe when you visit Southern Illinois University during your trip to Carbondale. Visit the shops and top-notch restaurants in this family-friendly area.

Harrah's Metropolis

Harrah's Metropolis

Why not roll the dice with a visit to Harrah's Metropolis during your visit to Metropolis? Visit the casinos and top-notch restaurants in this family-friendly area.

Learn more about Southern Illinois

Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

Southern Illinois which includes a sunset, forests and landscape views
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Top Southern Illinois Hotel Reviews