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Southern Illinois Hotels

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Go beyond your typical stay in Southern Illinois

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Check prices for these dates

Tonight
9 Nov - 10 Nov
Tomorrow
10 Nov - 11 Nov
This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

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Our top choices for Southern Illinois hotels

A bar area with a long counter, multiple chairs, and hanging light fixtures.

1. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.5 star property
Mount Vernon
9.8 out of 10, Exceptional, (1,868 reviews)
"Nice comfortable stay"
United States
Mei
The price is €112
includes taxes & fees
15 Nov - 16 Nov
Drury Plaza Hotel Mt. Vernon
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.

2. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (1,003 reviews)
"Very clean and everything was perfect!"
United States
Tad
The price is €76
includes taxes & fees
1 Dec - 2 Dec
SureStay Hotel by Best Western Whittington Rend Lake
A hotel with a covered entrance, stone pillars, and a modern design.

3. Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
2.5 star property
Mount Vernon
8.8 out of 10, Excellent, (1,004 reviews)
"Great spacious room. Breakfast was awesome and the helper was outstanding! Great food and coffee."
United States
Doug
The price is €108
includes taxes & fees
6 Dec - 7 Dec
Holiday Inn Express & Suites Mount Vernon by IHG
A modern kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave. There are red chairs and a table in the dining area.

4. Quality Inn Mount Vernon, IL

Quality Inn Mount Vernon, IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (724 reviews)
"Clean rooms, complimentary breakfast, great value."
United States
Ryan
The price is €73
includes taxes & fees
15 Nov - 16 Nov
Quality Inn Mount Vernon, IL
A breakfast buffet with various pastries, a bowl of oranges, and a waffle batter dispenser.

5. Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
2.5 star property
Mount Vernon
8.0 out of 10, Very good, (1,008 reviews)
"Everything was clean, nice hotel"
United States
Leslie
The price is €74
includes taxes & fees
15 Nov - 16 Nov
Super 8 by Wyndham Mt. Vernon IL
A self-service breakfast area with a coffee machine, refrigerated display case, and various food items.

6. Best Western Marion Hotel

Best Western Marion Hotel
2.5 star property
Marion
8.4 out of 10, Very good, (1,008 reviews)
"Staff was excellent!"
United States
Cornell
The price is €91
includes taxes & fees
10 Nov - 11 Nov
Best Western Marion Hotel
A hotel lobby with a large sofa, armchairs, a Christmas tree, and a patterned carpet.

7. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
3.0 star property
Mount Vernon
8.8 out of 10, Excellent, (732 reviews)
"Beautiful property very clean when you enter the lobby is very impressive in the staff was very helpful. Our room was clean in the morning. Breakfast was great."
United States
Susan
The price is €110
includes taxes & fees
12 Nov - 13 Nov
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
A spacious lobby with a beige sectional sofa, a fireplace, and a view of the outside through large glass doors.

8. Hampton Inn & Suites Effingham

Hampton Inn & Suites Effingham
2.5 star property
Effingham
9.6 out of 10, Exceptional, (803 reviews)
"The property was very clean even just staying a quick overnight traveling the room felt very comfortable."
United States
Scott
The price is €119
includes taxes & fees
23 Nov - 24 Nov
Hampton Inn & Suites Effingham
A Country Inn & Suites building with a covered entrance and a sign.

9. Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL
2.5 star property
Effingham
8.6 out of 10, Excellent, (1,014 reviews)
"Very nice stay"
United States
Samantha
The price is €88
includes taxes & fees
29 Nov - 30 Nov
Country Inn & Suites by Radisson, Effingham, IL
A Comfort Inn & Suites hotel with a covered entrance, multiple floors, and a landscaped front yard.

10. Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57
2.5 star property
Marion
9.4 out of 10, Exceptional, (1,001 reviews)
"Clean and comfortable room. Breakfast options were very good!"
United States
Suzan
The price is €116
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites Marion I-57
A spacious lobby with high ceilings, multiple seating areas, and large windows allowing natural light.

11. Drury Inn & Suites Marion

Drury Inn & Suites Marion
3.0 star property
Marion
9.4 out of 10, Exceptional, (1,003 reviews)
"Nice affordable with comfortable beds and good food."
United States
Heather
The price is €100
includes taxes & fees
15 Nov - 16 Nov
Drury Inn & Suites Marion
A La Quinta hotel with a stone facade, a covered entrance, and a parking lot.

12. La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
3.0 star property
Effingham
9.2 out of 10, Wonderful, (1,003 reviews)
"Very nice stay!!!"
United States
Steve
The price is €111
includes taxes & fees
15 Nov - 16 Nov
La Quinta Inn & Suites by Wyndham Effingham
An indoor swimming pool with clear water, marked depth lines, and a lifeguard sign.

13. Holiday Inn Express Metropolis by IHG

Holiday Inn Express Metropolis by IHG
2.5 star property
Metropolis
8.8 out of 10, Excellent, (1,001 reviews)
"Peaceful and pleasant stay"
United States
Regina
The price is €83
includes taxes & fees
7 Dec - 8 Dec
Holiday Inn Express Metropolis by IHG
A restaurant with multiple tables and booths, large windows, and a modern interior design.

14. The Principal Hotel

The Principal Hotel
3.5 star property
Columbia
9.6 out of 10, Exceptional, (466 reviews)
"Great Hotel!"
United States
Michael
The price is €98
includes taxes & fees
10 Nov - 11 Nov
The Principal Hotel
A hotel lobby with a reception desk, seating area, and a large screen TV.

15. Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1,092 reviews)
"Great bathroom"
United States
Bruce and Robin
The price is €119
includes taxes & fees
15 Nov - 16 Nov
Comfort Suites Mount Vernon
An indoor swimming pool with a clear view of the surrounding area, including a seating area with chairs and a view of the outdoors through large windows.

16. Best Western Delta Inn

Best Western Delta Inn
2.5 star property
Effingham
9.0 out of 10, Wonderful, (1,003 reviews)
"Great breakfast! The beds were so comfy! The staff was great!"
United States
Melissa Rae
The price is €84
includes taxes & fees
29 Nov - 30 Nov
Best Western Delta Inn
An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.

17. DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
4.0 star property
Mount Vernon
8.4 out of 10, Very good, (910 reviews)
"Loved the onsite bar and the location of the hotel"
United States
Tammi
The price is €129
includes taxes & fees
12 Nov - 13 Nov
DoubleTree by Hilton Mt. Vernon
A hotel lobby with a dining area, kitchen, and seating.

18. Best Western Heartland Inn

Best Western Heartland Inn
2.5 star property
Mattoon
8.2 out of 10, Very good, (652 reviews)
"Such a great stay! Everything was clean and everyone was so friendly. Will definitely stay again."
United States
Crystal
The price is €85
includes taxes & fees
11 Nov - 12 Nov
Best Western Heartland Inn
A modern living room with a fireplace, a bookshelf, a large wall clock, and a cozy seating area.

19. Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL
2.5 star property
Marion
8.6 out of 10, Excellent, (1,005 reviews)
"friendly staff, comfortable rooms, breakfast a plus."
United States
Rhonda
The price is €114
includes taxes & fees
15 Nov - 16 Nov
Country Inn & Suites by Radisson, Marion, IL
A large indoor swimming pool with a wooden interior, multiple windows, and a view of the outdoors.

20. Quality Inn Effingham North

Quality Inn Effingham North
2.5 star property
Effingham
8.6 out of 10, Excellent, (1,009 reviews)
"Basic motel but very nice. They were running behind on cleaning rooms so we had to wait to check in. Other than everything was very nice."
United States
Wayne
The price is €89
includes taxes & fees
6 Dec - 7 Dec
Quality Inn Effingham North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels in Southern Illinois

A bar area with a long counter, multiple chairs, and hanging light fixtures.

Drury Plaza Hotel Mt. Vernon

3.5 star property
Mount Vernon
View
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.

SureStay Hotel by Best Western Whittington Rend Lake

2.5 star property
Whittington
View
A hotel with a covered entrance, stone pillars, and a modern design.

Holiday Inn Express & Suites Mount Vernon by IHG

2.5 star property
Mount Vernon
View
A modern kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave. There are red chairs and a table in the dining area.

Quality Inn Mount Vernon, IL

2.5 star property
Mount Vernon
View
A breakfast buffet with various pastries, a bowl of oranges, and a waffle batter dispenser.

Super 8 by Wyndham Mt. Vernon IL

2.5 star property
Mount Vernon
View
9.8
Exceptional
1,868 reviews
8.8
Excellent
1,003 reviews
8.8
Excellent
1,004 reviews
7.8
Good
724 reviews
8.0
Very good
1,008 reviews
The price is €112
includes taxes & fees
15 Nov - 16 Nov
The price is €76
includes taxes & fees
1 Dec - 2 Dec
The price is €108
includes taxes & fees
6 Dec - 7 Dec
The price is €73
includes taxes & fees
15 Nov - 16 Nov
The price is €74
includes taxes & fees
15 Nov - 16 Nov
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking

Stay near popular Southern Illinois attractions

Garden of the Gods Recreation Area

9.8/10 (63 reviews)
See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.
See properties

Learn more about Southern Illinois

Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

See all hotels in Southern Illinois
A forested valley with autumn foliage, a rocky cliff, and a sunset.
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

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