Photo by Southernmost Illinois Tourism Bureau

Southern Illinois Hotel Guide - Business Hotels in Southern Illinois, Illinois

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Check availability on Southern Illinois Business Hotels

Tonight
22 Nov - 23 Nov
Tomorrow
23 Nov - 24 Nov
Next weekend
28 Nov - 30 Nov
In two weeks
5 Dec - 7 Dec

Top Southern Illinois Business Hotels

Free daily buffet breakfast
Holiday Inn Express Hotel & Suites Marion Northeast by IHG

Holiday Inn Express Hotel & Suites Marion Northeast by IHG

2.5 star property
Marion
9.0 out of 10, Wonderful, (922)
"Clean room, friendly staff, gym and pool"
United States
Samantha
The price is €116
includes taxes & fees
30 Nov - 1 Dec
Holiday Inn Express Hotel & Suites Marion Northeast by IHG
Lobby
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3.0 star property
Mount Vernon
9.6 out of 10, Exceptional, (1538)
"Friendly staff, wonderful accommodations."
United States
Susan
The price is €92
includes taxes & fees
30 Nov - 1 Dec
Drury Plaza Hotel Mt. Vernon
Lobby
La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham

3.0 star property
Effingham
9.2 out of 10, Wonderful, (1006)
"Excellent property and service was outstanding "
United States
Steven
The price is €90
includes taxes & fees
7 Dec - 8 Dec
La Quinta Inn & Suites by Wyndham Effingham
Front of property – evening/night
Hampton Inn Carbondale

Hampton Inn Carbondale

2.5 star property
Carbondale
8.4 out of 10, Very good, (606)
"Room was spotless, check in was quick, all personnel were courteous. "
United States
William
The price is €91
includes taxes & fees
30 Nov - 1 Dec
Hampton Inn Carbondale
Room, 2 Queen Beds, Non Smoking
Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL

2.5 star property
Effingham
8.8 out of 10, Excellent, (1007)
"Clean rooms and kind staff"
United States
Linda
The price is €90
includes taxes & fees
14 Dec - 15 Dec
Country Inn & Suites by Radisson, Effingham, IL
Lobby
SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake

2.5 star property
Whittington
8.8 out of 10, Excellent, (891)
"Great place to stay."
United States
Stephen
The price is €74
includes taxes & fees
30 Nov - 1 Dec
SureStay Hotel by Best Western Whittington Rend Lake
Exterior
Holiday Inn Carbondale-Conference Center by IHG

Holiday Inn Carbondale-Conference Center by IHG

3.0 star property
Carbondale
8.8 out of 10, Excellent, (633)
"Nice staff, clean rooms, awesome beds and pillows!"
United States
Kenneth
The price is €83
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Carbondale-Conference Center by IHG
Terrace/patio
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

2.5 star property
Mount Vernon
8.8 out of 10, Excellent, (1003)
"Good location, good breakfast"
United States
Don
The price is €107
includes taxes & fees
23 Nov - 24 Nov
Comfort Suites Mount Vernon
Exterior
Drury Inn & Suites Marion

Drury Inn & Suites Marion

3.0 star property
Marion
9.4 out of 10, Exceptional, (1004)
"Great hotel and very clean "
United States
Jose
The price is €78
includes taxes & fees
30 Nov - 1 Dec
Drury Inn & Suites Marion
Studio Suite, 1 King Bed, Non Smoking
Days Inn & Suites by Wyndham Casey

Days Inn & Suites by Wyndham Casey

2.0 star property
Casey
7.4 out of 10, Good, (824)
"Nice place, quiet, clean, and I would stay there again."
United States
Kym
The price is €61
includes taxes & fees
17 Dec - 18 Dec
Days Inn & Suites by Wyndham Casey
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southern Illinois Hotel Reviews

Best Western Delta Inn

Best Western Delta Inn

10/10 Excellent
"Front desk staff was so efficient and helpful. She had our room paperwork and key ready to go before we even arrived. Our check in took a quick minute and we were able to get to our room to rest after a long day of travel. The room was very clean along with the rest of the hotel. Breakfast was prepped and ready for guests with lots of options. The mango infused vitamin water option along with the juices was a special treat. It was so refreshing and I’ve never seen it before at any other hotels. Will stay here again. "
laura 1-night trip
Posted 5 days ago
Best Western Delta Inn

Explore a world of travel with Expedia

Frequently asked questions

How much do business-friendly hotels in Southern Illinois cost?
You'll pay between €61 and €116 per night for business-friendly hotels in Southern Illinois. Awesome deals on properties that cater to work-related travellers are a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southern Illinois?
That depends on your destination in Southern Illinois. Many business travellers to O'Fallon like to base themselves at Drury Inn & Suites St. Louis O'Fallon, IL. This 3-stars property comes with a swimming pool and complimentary breakfast. Hampton Inn O'Fallon is another top option if you're attending a conference or working remotely in O'Fallon. A swimming pool and an electric car charging station are among the handy amenities at this 2.5-stars getaway. When work takes you on the road, you can choose from multiple business-friendly hotels in Southern Illinois that have a total average guest review rating of 8.8.
How many business-friendly hotels are there in Southern Illinois?
Pick from 149 business-friendly hotels in Southern Illinois. Wherever your job is taking you, Expedia makes it a breeze to find the ideal space with the amenities you want.
What are the best cheap business-friendly hotels in Southern Illinois?
Keep costs low with Expedia's business-friendly hotels in Southern Illinois that start at €61 per night. A cheaper property in O'Fallon is Hampton Inn O'Fallon. Corporate guests rate it highly for its many amenities, including an electric car charging station and a swimming pool. If you're basing yourself in Effingham, choose Holiday Inn Express And Suites Effingham, an IHG Hotel. A swimming pool and a garden are among the conveniences provided for both business and leisure travellers. You'll find loads of free and interesting things to do wherever you go in Southern Illinois. If you have a meeting or conference in O'Fallon, try to find time to visit St. Clair Bowl. You can also go sightseeing for a song in Effingham. Mid America Motorworks, My Garage Museum is one of the best free attractions here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Southern Illinois that are also business friendly?
You'll discover some terrific family-friendly hotels that are also business friendly in Southern Illinois. If you're travelling to O'Fallon, look up Drury Inn & Suites St. Louis O'Fallon, IL. It offers handy amenities such as complimentary breakfast and a laundry service and has a 3-stars rating. Another property worth considering is Drury Inn & Suites St. Louis Fairview Heights. This 3-stars stay in O'Fallon is ideal for both leisure and business travellers and offers complimentary breakfast, a laundry service and much more. Once you've gotten work out of the way, get out and discover O'Fallon with the kids. Favourite family-friendly attractions include The Edge and St. Clair Bowl.
Why book your business-friendly hotel in Southern Illinois with Expedia?
At Expedia, we make it our job to help you locate an amazing stay at the right price. From luxurious, corporate-friendly properties to affordable hotels filled with handy amenities, you'll have your next work trip booked in a few easy clicks.
How can I find cheap business-friendly hotels in Southern Illinois?
When you're travelling for work in Southern Illinois, our "business friendly" filter will help you find the ideal hotel. From free WiFi to workspaces and meeting rooms, they have the amenities you need to be productive. Another useful tip? Refine your search by your budget and preferred star rating to view the most affordable options.
What is there to do in Southern Illinois near my business-friendly hotel?
Southern Illinois has so much to see and do, it can be tricky to figure out where to start. If you're spending a few nights in O'Fallon, The Edge is a much-loved attraction here.