Southwest Illinois Hotel Guide - Hotels with Spa in Southwest Illinois, Illinois

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Southwest Illinois Hotels with Spa

Tonight
3 Aug - 4 Aug
Tomorrow
4 Aug - 5 Aug
Next weekend
8 Aug - 10 Aug
In two weeks
15 Aug - 17 Aug

Top Southwest Illinois Hotels with Spa

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Exterior

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1006)
"Great place to stay. "
The price is €96
includes taxes & fees
10 Aug - 11 Aug
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Four Seasons Hotel St Louis
Rooftop bar

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (1002)
"Great hotel, loved the room"
The price is €429
includes taxes & fees
19 Aug - 20 Aug
Four Seasons Hotel St Louis
21C Museum Hotel St Louis
Exterior

21C Museum Hotel St Louis

4.5 star property
9.0 out of 10, Wonderful, (1283)
"Great place to stay. "
The price is €158
includes taxes & fees
31 Aug - 1 Sept
21C Museum Hotel St Louis
The Ritz-Carlton, St. Louis
Meeting facility

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (540)
"Wish they still had a pool"
The price is €582
includes taxes & fees
10 Aug - 11 Aug
The Ritz-Carlton, St. Louis
Ameristar Casino Resort and Spa
6 restaurants, breakfast served

Ameristar Casino Resort and Spa

4.5 star property
8.4 out of 10, Very good, (1004)
"NICE AREA TO STAY"
The price is €185
includes taxes & fees
10 Aug - 11 Aug
Ameristar Casino Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Southwest Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"Love the renovations. Enjoy the kick backs. We stay here every year for our family reunion. Hotel is consistently cleans and very friendly staff. Happy the hotel is moving away from paper plates and utensils. My only comment - bring back the eggs, they were a family favorite. "
Kimberly 2-night trip
Posted 2 days ago
Drury Plaza Hotel Mt. Vernon