A calm lake surrounded by trees and vegetation.

Southwest Illinois Hotel Guide - Hotels with Spa in Southwest Illinois, Illinois

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Check availability on Southwest Illinois Hotels with Spa

Tonight
16 Oct - 17 Oct
Tomorrow
17 Oct - 18 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Southwest Illinois hotels with a spa

A modern spa room with a large hot tub, a glass wall with a reflective pattern, and a ceiling with a skylight.
A casino interior with slot machines, a large chandelier, and a carpeted floor.
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.
A hotel reception desk with a modern chandelier, a sign indicating 'SPA' coming soon, and two receptionists at their stations.

1. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
  • Luxurious spa retreat with hot stone massages, sauna, and seasonal pools awaits at this casino resort with attentive staff and fine dining.
€124
includes taxes & fees
19 Oct - 20 Oct
Walker's Bluff Casino Resort
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A room with a bed, a nightstand with a lamp, a painting on the wall, and a radiator.
A two-story building with a dark entrance, large windows, and a brick facade.
A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.

2. Truitt Hotel

Truitt Hotel
Lafayette Square
€182
includes taxes & fees
18 Oct - 19 Oct
Truitt Hotel
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

3. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
  • Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
€96
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A modern bathroom with a bathtub, a vanity with a mirror, and a shower area.

4. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
€154
includes taxes & fees
15 Nov - 16 Nov
21C Museum Hotel St Louis
A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
A bar area with multiple seating arrangements, a stage, and a chandelier.

5. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
€181
includes taxes & fees
16 Nov - 17 Nov
Ameristar Casino Resort and Spa
A couple relaxing by a window overlooking a bridge and water.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.
A modern hotel lobby with a glass facade, seating area, and a staircase.

6. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
€391
includes taxes & fees
25 Oct - 26 Oct
Four Seasons Hotel St Louis
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A couple standing on a balcony with a cityscape view.
A bar area with leather seating, a bar counter, and shelves of bottles.

7. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
€603
includes taxes & fees
1 Nov - 2 Nov
The Ritz-Carlton, St. Louis
View all properties

Choose what matters most at spa hotels in Southwest Illinois

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Southwest Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"Huge room and very clean. Amazing hotel. Well worth the money. Kickbacks was a nice snack for us, but didn't care for the chili. Breakfast was very good. It was busy but the food area is large so it didn't seem over packed. We would stay here again!"
Kristin 1-night trip
Posted 4 hours ago
Drury Plaza Hotel Mt. Vernon
Quality Inn O'Fallon - St. Louis - Shiloh

Quality Inn O'Fallon - St. Louis - Shiloh

8/10 Good
"It was disappointing to not have any protein options for breakfast, and only apples as fruit."
Clara 4-night trip
Posted 16 hours ago
Quality Inn O'Fallon - St. Louis - Shiloh
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent
"The staff were so friendly and helpful and the property and rooms well maintained. Nice mattresses and bedding—we slept well. Really liked the evening food and beverages that were offered. Very nice stay overall!"
Jennie 1-night trip
Posted 20 hours ago
Drury Inn & Suites St. Louis Fairview Heights
Drury Inn & Suites Marion

Drury Inn & Suites Marion

10/10 Excellent
"Nice affordable with comfortable beds and good food."
Heather 1-night trip
Posted 1 day ago
Drury Inn & Suites Marion
Best Western Marion Hotel

Best Western Marion Hotel

8/10 Good
"The room was clean and comfortable. Staff was friendly and check in went smoothly. Breakfast was good and coffee is always available. Hotel is being remodeled. Hallways are a mess now. Stay was excellent overall."
David 1-night trip
Posted 3 days ago
Best Western Marion Hotel

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