St. Louis Hotel Guide. Hotels in Tower Grove South, St. Louis, United States of America

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Our top choices for Tower Grove South hotels

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 6.8 km from Tower Grove South
8.4 out of 10, Very good, (4011)
"Everything was great!"
United States
Kathryn
The price is €85
includes taxes & fees
2 Jan - 3 Jan 2026
Hyatt Regency St. Louis at The Arch

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis, 6.7 km from Tower Grove South
8.8 out of 10, Excellent, (1157)
"Really nice hotel!"
United States
DARIN
The price is €81
includes taxes & fees
23 Dec - 24 Dec
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 6.7 km from Tower Grove South
9.4 out of 10, Exceptional, (3289)
"Our stay was very enjoyable. Location was great and kids loved the indoor pool!"
United States
Christy
The price is €134
includes taxes & fees
28 Dec - 29 Dec
Drury Plaza Hotel St. Louis at the Arch

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 6.9 km from Tower Grove South
8.8 out of 10, Excellent, (1245)
"Great hospitality"
United States
Alejandro
The price is €111
includes taxes & fees
25 Dec - 26 Dec
Embassy Suites by Hilton St. Louis Downtown

Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL
3.0 star property
28.5 km from Tower Grove South
9.6 out of 10, Exceptional, (1000)
"Excellent location, clean and spacious room, great morning breakfast with numerous choices and of course helpful and pleasant staff."
United States
David
The price is €101
includes taxes & fees
28 Dec - 29 Dec
Drury Inn & Suites St. Louis O'Fallon, IL

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
Downtown St. Louis, 7.1 km from Tower Grove South
8.8 out of 10, Excellent, (1175)
"Breakfast was great and this was my seventh year staying there."
United States
Derick
The price is €97
includes taxes & fees
29 Dec - 30 Dec
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis, 6.9 km from Tower Grove South
8.8 out of 10, Excellent, (1018)
"My second time staying there as always it was lovely "
United States
Nina
The price is €104
includes taxes & fees
25 Dec - 26 Dec
Hilton Pennywell St. Louis at the Arch

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
9 km from Tower Grove South
8.8 out of 10, Excellent, (3031)
"Clean room, good breakfast and good location "
United States
Martin
The price is €89
includes taxes & fees
21 Dec - 22 Dec
Clayton Plaza Hotel & Extended Stay

Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown
2.5 star property
Downtown West, 6.4 km from Tower Grove South
7.6 out of 10, Good, (592)
"Breakfast was delicious and room was comfy "
United States
Ronnesha
The price is €81
includes taxes & fees
4 Jan - 5 Jan 2026
Tru By Hilton St. Louis Downtown

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
7.5 km from Tower Grove South
9.0 out of 10, Wonderful, (1449)
"Awesome place to stay!!"
United States
Kaitlyn
The price is €110
includes taxes & fees
25 Dec - 26 Dec
River City Casino & Hotel

The Principal Hotel

The Principal Hotel
3.5 star property
18 km from Tower Grove South
9.8 out of 10, Exceptional, (191)
"Great place. Very nice rooms, new and clean."
United States
Jeff
The price is €107
includes taxes & fees
21 Dec - 22 Dec
The Principal Hotel

Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
Downtown St. Louis, 6.7 km from Tower Grove South
9.0 out of 10, Wonderful, (1010)
"Was a great stay. "
United States
Lorilyn
The price is €98
includes taxes & fees
18 Jan - 19 Jan 2026
Courtyard by Marriott St. Louis Downtown/Convention Center

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
27.2 km from Tower Grove South
9.6 out of 10, Exceptional, (1036)
"Absolutely amazing stay very nice play our family stays there every time very kid friendly"
United States
Matthew
The price is €128
includes taxes & fees
18 Jan - 19 Jan 2026
Drury Plaza Hotel St. Louis Chesterfield

Moonrise Hotel

Moonrise Hotel
4.0 star property
7.5 km from Tower Grove South
9.0 out of 10, Wonderful, (1914)
"Clean rooms, good coffee and fresh muffins and friendly service."
United States
Colleen
The price is €120
includes taxes & fees
28 Dec - 29 Dec
Moonrise Hotel

Pear Tree Inn St. Louis Convention Center

Pear Tree Inn St. Louis Convention Center
3.0 star property
Downtown St. Louis, 7.1 km from Tower Grove South
9.0 out of 10, Wonderful, (1053)
"Was a lovely place to stay! Everyone was kind and friendly. "
United States
Shandee
The price is €94
includes taxes & fees
26 Dec - 27 Dec
Pear Tree Inn St. Louis Convention Center

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
19.3 km from Tower Grove South
8.0 out of 10, Very good, (1042)
"Everything was clean and friendly staff overall good experience "
United States
dennis
The price is €84
includes taxes & fees
22 Dec - 23 Dec
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
27.8 km from Tower Grove South
9.4 out of 10, Exceptional, (1001)
"The staff were awesome "
United States
Corey
The price is €109
includes taxes & fees
11 Jan - 12 Jan 2026
Country Inn & Suites by Radisson, St. Charles Historic District

Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia
2.5 star property
17.6 km from Tower Grove South
8.6 out of 10, Excellent, (476)
"Breakfast was great and a very good atten"
United States
John
The price is €91
includes taxes & fees
12 Jan - 13 Jan 2026
Hampton Inn St. Louis - Columbia

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
24.8 km from Tower Grove South
7.4 out of 10, Good, (1000)
"Clean lobby, super friendly staff, effortless check in. There’s even a small market with food and essentials right next to the check in desk. "
United States
Jen
The price is €70
includes taxes & fees
24 Dec - 25 Dec
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis, 6.3 km from Tower Grove South
9.4 out of 10, Exceptional, (1105)
"Clean room! Staff were very helpful and nice! Room exceeded my expectations, food was great, friendly environment! Best hotel in St.Louis hands down!!!"
United States
Twoun
The price is €151
includes taxes & fees
20 Dec - 21 Dec
Live by Loews - St.Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Tower Grove South

Find the best Tower Grove South areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Top Tower Grove South Hotel Reviews

Frequently asked questions

What's it like in Tower Grove South?
Travellers will be sure to find plenty to entertain them in St. Louis's Tower Grove South neighbourhood. Consider a visit to Cherokee Street as part of your Tower Grove South travel plans.
How many hotels will I find in the Tower Grove South area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 39 Tower Grove South hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Tower Grove South, will I receive a refund?
Yes, the majority of hotel bookings are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the top deals on offer in Tower Grove South.
What is there to do in this St. Louis neighbourhood?
Cherokee Street is an attraction you might want to check out while you're in Tower Grove South. While you're out sightseeing in St. Louis, make sure that you visit other sights such as Tower Grove Tennis Center or Missouri Botanical Gardens and Arboretum.

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